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This study aims to develop a 30 kHz/12 kW silicon carbide (SiC)/Si integrated hybrid power module (iHPM) for variable frequency drive applications, particularly industrial servo motor control, and, additionally, to theoretically and experimentally assess its dynamic characteristics and efficiency during operation. This iHPM integrates a brake circuit, a three-phase Si rectifier, and a three-phase SiC inverter within a single package to achieve a minimal current path. A space-vector pulse width modulation (SVPWM) scheme is used to control the inverter power switches. In order to reduce parasitic inductance and power loss, an inductance cancellation design is implemented in the Si rectifier and SiC inverter. The switching transients and their parasitic effects during a three-phase operation are assessed through an electromagnetic-circuit co-simulation model, by which the power loss and efficiency of the iHPM are estimated. The modeled parasitic inductance of the inverter is validated through inductance measurement, and the effectiveness of the simulated results in terms of switching transients and efficiency is verified using the experimental results of the double pulse test and open-loop inverter operation, respectively. In addition, the power loss and efficiency of the SiC MOSFET inverter are experimentally compared against those of a commercial Si IGBT inverter. [ABSTRACT FROM AUTHOR]

In this paper, a localized boundary knot method is adopted to solve two-dimensional inverse Cauchy problems, which are controlled by a second-order linear differential equation. The localized boundary knot method is a numerical method based on the local concept of the localization method of the fundamental solution. The approach is formed by combining the classical boundary knot method with the localization method. It has the potential to solve many complex engineering problems. Generally, in an inverse Cauchy problem, there are no boundary conditions in specific boundaries. Additionally, in order to be close to the actual engineering situation, a certain level of noise is added to the known boundary conditions to simulate the measurement error. The localized boundary knot method can be used to solve two-dimensional Cauchy problems more stably and is truly free from mesh and numerical quadrature. In this paper, the stability of the method is verified by using multi-connected domain and simply connected domain examples in Laplace equations. [ABSTRACT FROM AUTHOR]

The localized method of fundamental solutions (LMFS) is a domain-type, meshless numerical method. Compared with numerical methods that have a high grid dependence, it does not require grid generation and numerical integration, so it can effectively improve computational efficiency and avoid complex integration processes. Moreover, it is formed using the traditional method of fundamental solutions (MFS) and the localization approach. Previous studies have shown that the MFS may produce a dense and ill-conditioned matrix. However, the proposed LMFS can yield a sparse system of linear algebraic equations, so it is more suitable and effective in solving complicated engineering problems. In this article, LMFS was used to solve eigenfrequency problems in electromagnetic waves, which were controlled using two-dimensional Helmholtz equations. Additionally, the resonant frequencies of the eigenproblem were determined by the response amplitudes. In order to determine the eigenfrequencies, LMFS was applied for solving a sequence of inhomogeneous problems by introducing an external source. Waveguides with different shapes were analyzed to prove the stability of the present LMFS in this paper. [ABSTRACT FROM AUTHOR]

In this study, an efficient localized method of fundamental solution (LMFS) is applied to nonlinear heat conduction with mixed boundary conditions. Since the thermal conductivity is temperature-dependent, the Kirchhoff transformation is used to transform the nonlinear partial differential equations (PDEs) into Laplace equations with nonlinear boundary conditions. Then the LMFS is applied to the governing equation, and the nonlinear equations are treated by the fictitious time integration method (FTIM). Both 2D and 3D numerical examples are proposed to verify the effectiveness of the LMFS. [ABSTRACT FROM AUTHOR]

Enrofloxacin (EFX) reacting with Ca(II) afforded a new complex, [Ca(EFX)2(H2O)4] (EFX-Ca), which was structurally characterized both in solid and solution chemistry. E. coli and S. typhi were tested to be the most sensitive strains for EFX-Ca. The LD50 value of EFX-Ca in mice was 7736 mg/kg, implying the coordination of EFX to Ca(II) effectively reduced its acute toxicity. EFX-Ca also decreased the plasma-binding rate and enhanced the drug distribution in rats along with longer elimination half-life. EFX-Ca also showed similar low in vivo acute toxicity and higher anti-inflammation induced by H2O2 or CuSO4 in zebrafish, with reactive oxygen species (ROS)-related elimination. The therapeutic effects of EFX-Ca on two types (AA and 817) of E. coli-infected broilers were also better than those of EFX, with cure rates of 78% and 88%, respectively. EFX-Ca showed promise as a bio-safe metal-based veterinary drug with good efficacy and lower toxicity. [ABSTRACT FROM AUTHOR]

The smut fungus Ustilago esculenta infects Zizania latifolia and induces stem expansion to form a unique vegetable named Jiaobai. Although previous studies have demonstrated that hormonal control is essential for triggering stem swelling, the role of hormones synthesized by Z. latifolia and U. esculenta and the underlying molecular mechanism are not yet clear. To study the mechanism that triggers swollen stem formation, we analyzed the gene expression pattern of both interacting organisms during the initial trigger of culm gall formation, at which time the infective hyphae also propagated extensively and penetrated host stem cells. Transcriptional analysis indicated that abundant genes involving fungal pathogenicity and plant resistance were reprogrammed to maintain the subtle balance between the parasite and host. In addition, the expression of genes involved in auxin biosynthesis of U. esculenta obviously decreased during stem swelling, while a large number of genes related to the synthesis, metabolism and signal transduction of hormones of the host plant were stimulated and showed specific expression patterns, particularly, the expression of ZlYUCCA9 (a flavin monooxygenase, the key enzyme in indole-3-acetic acid (IAA) biosynthesis pathway) increased significantly. Simultaneously, the content of IAA increased significantly, while the contents of cytokinin and gibberellin showed the opposite trend. We speculated that auxin produced by the host plant, rather than the fungus, triggers stem swelling. Furthermore, from the differently expressed genes, two candidate Cys2-His2 (C2H2) zinc finger proteins, GME3058_g and GME5963_g, were identified from U. esculenta, which may conduct fungus growth and infection at the initial stage of stem-gall formation. [ABSTRACT FROM AUTHOR]

This study introduces an effective and efficient dynamic electro-thermal coupling analysis (ETCA) approach to explore the electro-thermal behavior of a three-phase power metal–oxide–semiconductor field-effect transistor (MOSFET) inverter for brushless direct current motor drive under natural and forced convection during a six-step operation. This coupling analysis integrates three-dimensional electromagnetic simulation for parasitic parameter extraction, simplified equivalent circuit simulation for power loss calculation, and a compact Foster thermal network model for junction temperature prediction, constructed through parametric transient computational fluid dynamics (CFD) thermal analysis. In the proposed ETCA approach, the interactions between the junction temperature and the power losses (conduction and switching losses) and between the parasitics and the switching transients and power losses are all accounted for. The proposed Foster thermal network model and ETCA approach are validated with the CFD thermal analysis and the standard ETCA approach, respectively. The analysis results demonstrate how the proposed models can be used as an effective and efficient means of analysis to characterize the system-level electro-thermal performance of a three-phase bridge inverter. [ABSTRACT FROM AUTHOR]

This study attempts to investigate the warpage behavior of a flip chip package-on-package (FCPoP) assembly during fabrication process. A process simulation framework that integrates thermal and mechanical finite element analysis (FEA), effective modeling and ANSYS element death-birth technique is introduced for effectively predicting the process-induced warpage. The mechanical FEA takes into account the viscoelastic behavior and cure shrinkage of the epoxy molding compound. In order to enhance the computational and modeling efficiency and retain the prediction accuracy at the same time, this study proposes a novel effective approach that combines the trace mapping method, rule of mixture and FEA to estimate the effective orthotropic elastic properties of the coreless substrate and core interposer. The study begins with experimental measurement of the temperature-dependent elastic and viscoelastic properties of the components in the assembly, followed by the prediction of the effective elastic properties of the orthotropic interposer and substrate. The predicted effective results are compared against the results of the ROM/analytical estimate and the FEA-based effective approach. Moreover, the warpages obtained from the proposed process simulation framework are validated by the in-line measurement data, and good agreement is presented. Finally, key factors that may influence process-induced warpage are examined via parametric analysis. [ABSTRACT FROM AUTHOR]

In this paper, a localized boundary knot method is proposed, based on the local concept in the localized method of fundamental solutions. The localized boundary knot method is formed by combining the classical boundary knot method and the localization approach. The localized boundary knot method is truly free from mesh and numerical quadrature, so it has great potential for solving complicated engineering applications, such as multiply connected problems. In the proposed localized boundary knot method, both of the boundary nodes and interior nodes are required, and the algebraic equations at each node represent the satisfaction of the boundary condition or governing equation, which can be derived by using the boundary knot method at every subdomain. A sparse system of linear algebraic equations can be yielded using the proposed localized boundary knot method, which can greatly reduce the computer time and memory required in computer calculations. In this paper, several cases of simply connected domains and multi-connected domains of the Laplace equation and bi-harmonic equation are demonstrated to evidently verify the accuracy, convergence and stability of this proposed meshless method. [ABSTRACT FROM AUTHOR]