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Augmented reality (AR) is a technology whose presence has increased in the field of education in recent years. However, its role in secondary education has not been thoroughly explored. Therefore, this research aims to analyse the influence of AR on the motivation of students at this stage while considering gender and previous information and communication technology (ICT) experience. This research uses a quantitative methodology that follows Keller's Attention, Relevance, Confidence and Satisfaction (ARCS) motivational model. We implemented this instructional design model for a sample of 321 students from the same educational centre. They were divided into two categories: an experimental group (n = 159) and a control group (n = 162). The control group were studied in a slide-based learning environment, while the experimental group worked with an AR mobile application. For data collection, we used the Instructional Materials Motivation Survey (IMMS). The results showed that the students who used AR displayed greater motivation, highlighting great interest in the integration of this technology into the learning process. However, no significant differences were obtained in the motivation of the students according to gender and previous experience with the use of ICT. In conclusion, this research shows that the use of AR improves motivation in secondary education. [ABSTRACT FROM AUTHOR]

Psychological flow has been measured in several areas to analyse to what extent users are engaged in particular tasks, and is relevant in the design of products like software, videogames, and eLearning courses. Although there is an unknown number of questionnaires for evaluating different aspects of psychological flow, the research problem faced in this paper is the analysis of the validity of these questionnaires, since it has only been probed for some of them. Thus, our goal is to synthesize the current evidence regarding validated questionnaires in the English language for psychological flow measurement by conducting a systematic review according to the PRISMA framework. As a result, we found a total number of 34 validated questionnaires to assess flow. The number of their items ranged from 3 to 66, while 63 different dimensions of optimal experiences were taken into consideration. Moreover, the contexts of use differed, including methods to assess flow intensity, prevalence, variations, proneness, metacognitions, in crowds, observed, as dimensions of autotelic personalities, or to differentiate flow from clutch states. As a consequence, this paper facilitates the selection of the questionnaires for research or applied aims, far beyond the classic dichotomy of prevalence–proneness. Moreover, we present a reinterpretation of the nine-dimensional scheme of flow in stages, and recommend future research for engineering and computer science. [ABSTRACT FROM AUTHOR]

New technologies currently play a fundamental role in the educational context. As a result, augmented reality (AR) has recently gained a presence in educational centres. However, this educational technology has not been explored in depth at the secondary education level. Therefore, this research aims to analyse the impact of augmented reality on the academic performance of secondary education students, considering gender and the students' attitudes toward this technology. In this mixed-method research based on convenient sampling, 321 students aged 14 to 17 years from the same secondary education school were assigned to an experimental group (n = 159) and a control group (n = 162). The control group used a traditional methodology in a slide-based learning environment, while the experimental group worked with an AR mobile application (ComputAR) designed with the same concepts. The data collection instruments used comprised a pre-test/post-test in both groups and semi-structured interviews in the experimental group. The results showed that the students who used augmented reality achieved better grades, highlighting the potential benefits of integrating this technology into the teaching process. No significant differences were observed regarding the gender of the students. In conclusion, this study provides findings that encourage the use of augmented reality in secondary schools. [ABSTRACT FROM AUTHOR]

English has become the most important language for communication worldwide, but learning it as a second language presents multiple challenges. Given its multimedia nature, mobile learning is an ally in learning this language. However, although the use of mobile devices in English education has been broadly documented, there is little evidence of its effect on students' learning. This article presents a meta-analysis of 62 studies to assess the effects of mobile learning on students' learning. Moreover, the study considered the moderating effect of education level, pedagogical approach, learning environment, mobile device, and control treatment. The results show that mobile learning has a large effect (g = 0.89) on students' learning. Regarding education level, the best results were found at the Bachelor's level. Similarly, collaborative learning provided the best results among the pedagogical approaches. As for the learning environment, semi-formal settings, such as field trips and outdoor activities, performed better than formal settings within classrooms or laboratories. Furthermore, smartphones yielded better results than any other mobile device. Finally, the results indicated that mobile learning produces better results than traditional lectures, traditional pedagogical tools, or other multimedia resources. Therefore, it should be promoted as a pedagogical alternative to foster quality education for all. [ABSTRACT FROM AUTHOR]

This article describes the serious game Compete!, developed within the European Erasmus+ framework, that aims to teach soft skills to higher education students in order to increase their employability. Despite the increasing relevance of soft skills for successful entry into the labour market, these are often overlooked in higher education. A participatory learning methodology based on a gamification tool has been used for this purpose. The game presents a series of scenarios describing social sustainability problems that require the application of soft skills identified as key competencies in a field study across different European countries. These competencies are creative problem-solving, effective communication, stress management, and teamwork. On completion of each game scenario and the game itself, students receive an evaluation of both their soft skills and the strategic and operational decisions they have made. In the evaluation of these decisions, both the economic and sustainability aspects of the decision are assessed. The teacher can then address the competencies and sustainability issues using the different game scenarios, thus creating higher motivation and deeper understanding amongst the students. This hybrid learning methodology incorporates digital tools for the cross-curricular teaching and learning of sustainability and soft skills. In conclusion, this article describes a possible method of incorporating soft skills in higher education; this complements students' technical knowledge while helping to achieve Sustainable Development Goals. [ABSTRACT FROM AUTHOR]

The current study aims to adopt a new model for creating innovative OERs. The model, called 'GHOSHEH', supports OERs through multiple learner-centered strategies with authentic assessments, and focuses on practice and reflection. The model is internally validated based on international experts' reviews. Rogers' process for diffusion of innovations is followed in order to introduce and adopt the GHOSHEH model based on a sample of 117 teachers and experts from different states in the Arab world, including Palestine, Jordan, Saudi Arabia, Oman, Kuwait, UAE, Iraq, and Yemen. Mixed methods research is used: qualitative data are collected from a descriptive case study, and quantitative data are collected from the responses of the participants to a questionnaire about adopting the GHOSHEH model. Results reveal that the model involves four main processes: The first is analysis of content and context. The second is implementing sequenced activities that promote reflection, problem solving, and collaboration. The third is a formative assessment followed by providing continuous feedback. The fourth is peer sharing of the created OERs. Moreover, results show that teachers and experts from different states in the Arab world overwhelmingly adopted the model, and there is evidence of the model's advantages, simplicity, compatibility, trialability, and observability. [ABSTRACT FROM AUTHOR]

This study examines the role of educational games in compensating for educational loss and their impact on students' motivation towards learning during crises in Palestine and Iraq. Additionally, the study considers the challenges facing the employment of this strategy and ways to overcome these challenges. By performing separate open semi-structured interviews with a group of 10 educators from university professors, teachers, and educational supervisors, the study used the qualitative descriptive approach which designs multiple case studies. The results showed the prominent role that educational games play in increasing students' motivation towards learning and compensating for educational loss through what they add to the fun and suspense in the learning process and how they shorten time and effort and help students to engage and cooperate in acquiring knowledge, skills, and values. The results also reveal common challenges that face the employment of educational games. These challenges are social, economic, technological, challenges related to school environment, and psychological challenges. The study shows the possibility of overcoming these challenges by providing funding sources, preparing plans to employ educational games, and developing teachers' capabilities to implement them in their teaching practices. [ABSTRACT FROM AUTHOR]

Users show a growing interest in expanding the implementation of digital tools as a support of technical and management issues in healthcare. This medical care has focused on telemedicine but does not include the recognition of needs as an important part of patient-centred healthcare. Nurses interact with patients at critical times in their life journeys, including birth and death, which are historical events linked with religious beliefs. Furthermore, large migration flows have led to multicultural societies in which religion and spirituality are experienced in distinct ways by different people. Finally, most healthcare professionals lack the proper skills to handle the spiritual needs of their patients, especially for core and digital competences. This article shows the results of qualitative research applying as a research tool an open-ended questionnaire, which allows detecting the educational needs for nurses' interventions aimed at providing spiritual support to their patients using digital tools. The results obtained reveal that nurses need education and training on fundamental spiritual concepts and digital competencies to meet the multiple demands of their patients' spiritual needs. Finally, we present an open digital educational proposal for the development of competencies for nurses and other health professionals to provide spiritual care with the support of digital tools. [ABSTRACT FROM AUTHOR]

Background: The intelligent processes automation has been cataloged as one of the most potential and strategic technology solutions to develop a corporate digital transformation. Method: This paper introduces essential concepts to create Intelligent Process Automation (IPA) in industries and proposes a framework to implement IPA technologies successfully. The approach involves: firstly, assembling a good implementation setup and deeply researching the process using process mining techniques. Secondly, choosing and locating the best AI technology inside the IPA. Finally, defining an appropriate architecture of the IPA. Results: The paper illustrates an IPA use case in the manufacturing industry, where it is possible to automate the process of sending production orders to a manufacturing plant and optimize waste and plant capacity significantly. Conclusions: The research depicts the potential of intelligent process automation and its quantifiable benefits in the manufacturing process, and the contribution can be applied to different enterprises with a global context. [ABSTRACT FROM AUTHOR]

Textbooks are essential components in the learning process. They assist in achieving educational learning outcomes and developing social and cultural values. However, limited studies provide comprehensive frameworks for comparing textbooks. Most have focused on a specific textbook perspective within a particular discipline. Therefore, this study used a triangulation method to develop a comprehensive framework for textbook comparison. Through a systematic literature review and a two-round Fuzzy Delphi method with 155 textbook experts, a textbook comparison framework with four indicators (structure, content, expectations, and language) was developed. Additionally, some of the developed framework indicators and sub-indicators could be relevant for comparing textbooks in a particular discipline. For example, the page count sub-indicator was proven to be useful for comparing humanities and social science textbooks but not natural science textbooks. The findings of this study could facilitate the process of comparing textbooks, hence promoting the understanding of knowledge design and acquisition in different contexts, such as when comparing textbooks from different countries. [ABSTRACT FROM AUTHOR]

Learning analytics (LA) has become a key area of study in educology, where it could assist in customising teaching and learning. Accordingly, it is precisely this data analysis technique that is used in a sensor—AnalyTIC—designed to identify students who are at risk of failing a course, and to prompt subsequent tutoring. This instrument provides the teacher and the student with the necessary information to evaluate academic performance by using a risk assessment matrix; the teacher can then customise any tutoring for a student having problems, as well as adapt the course contents. The sensor was validated in a study involving 39 students in the first term of the Environmental Engineering program at the Cooperative University of Colombia. Participants were all enrolled in an Algorithms course. Our findings led us to assert that it is vital to identify struggling students so that teachers can take corrective measures. The sensor was initially created based on the theoretical structure of the processes and/or phases of LA. A virtual classroom was built after these phases were identified, and the tool for applying the phases was then developed. After the tool was validated, it was established that students' educational experiences are more dynamic when teachers have sufficient information for decision-making, and that tutoring and content adaptation boost the students' academic performance. [ABSTRACT FROM AUTHOR]

Patients with dementia present epilepsy more frequently than the general population. Seizures are more common in patients with Alzheimer's disease (AD), dementia with Lewy bodies (LBD), frontotemporal dementia (FTD) and progressive supranuclear palsy (PSP) than in other dementias. Missense mutations in the microtubule associated protein tau (MAPT) gene have been found to cause familial FTD and PSP, while the P301S mutation in MAPT has been associated with early-onset fast progressive dementia and the presence of seizures. Brains of patients with AD, LBD, FTD and PSP show hyperphosphorylated tau aggregates, amyloid-β plaques and neuropil threads. Increasing evidence suggests the existence of overlapping mechanisms related to the generation of network hyperexcitability and cognitive decline. Neuronal overexpression of tau with various mutations found in FTD with parkinsonism-linked to chromosome 17 (FTDP-17) in mice produces epileptic activity. On the other hand, the use of certain antiepileptic drugs in animal models with AD prevents cognitive impairment. Further efforts should be made to search for plausible common targets for both conditions. Moreover, attempts should also be made to evaluate the use of drugs targeting tau and amyloid-β as suitable pharmacological interventions in epileptic disorders. The diagnosis of dementia and epilepsy in early stages of those diseases may be helpful for the initiation of treatments that could prevent the generation of epileptic activity and cognitive deterioration. [ABSTRACT FROM AUTHOR]

This paper presents and analyses solutions where open education and open science were utilised to reduce the impact of the COVID-19 pandemic on education. The COVID-19 outbreak and associated lockdowns created huge challenges in school and higher education, demanding sudden responses which aimed to sustain pedagogical quality. Responses have varied from conservative to radically innovative. Universally, the COVID-19 pandemic disrupted and shocked societies worldwide, and education systems were on the front line. The lockdowns largely stopped face-to-face and formal education in almost all countries, and in most cases, distance learning soon became the 'new normal'. A central challenge concerned sustaining educational visions and ideals in such circumstances. To better understand the state of the art in the educational landscape, we collected case studies from 13 countries during the first year of the pandemic starting on 11 March 2020 (when the World Health Organization declared a pandemic). This paper presents summaries of the full country reports that were collected and describe lessons learned. Our overall aim was to identify good practices and recommendations from the collected case studies that can be taken forward in the future. We categorised the responses on the three generic educational levels (macro, meso and micro) and identified seven key aspects and trends that are valid for all or most countries: (1) formal education at a distance for first time; (2) similar approaches for formal education; (3) missing infrastructure and sharing open educational resources; (4) diverse teaching and learning methods and practices; (5) open education and access to open educational resources; (6) urgent need for professional development and training for teachers and (7) assessing and monitoring learning environments, teachers and students. Finally, we identified key recommendations on how open education and open science can benefit formal education in schools and universities in the future, namely, improved awareness of open educational practices, provision of ICT infrastructure, embracing and sustaining the practice of open access publications and OERs, capacity building for stakeholders and finally encouraging research and development in the area of open education and open science. We found significant evidence for the proposition that open education and open science can support both traditional face-to-face and distance learning. [ABSTRACT FROM AUTHOR]

This study undertook a bibliometric mapping analysis of research papers on Open Educational Practices (OEP) in the Web of Science and Scopus databases. This study functions as a guide for new research, serving to identify trends in the OEP field and compare the existing research so as to identify gaps and promising future paths. A total of 635 studies were obtained; however, only 156 were finally selected for the analysis. VOSviewer software was used to identify the most frequently used keywords and terms in the abstracts and titles. This software was also used to analyse the studies for co-authorship and citations. The findings showed that research on OEP started in 2007 and focused on higher education, including open and distance higher education. Most of the OEP studies were published in English as journal articles, in particular, many were published in Distance Education, International Review of Research in Open and Distributed Learning, and Open Praxis. The United Kingdom, Spain, and Australia were the top contributors to the OEP literature. The analysis of keywords and terms in the titles and abstracts revealed that current OEP trends covered only open pedagogy and open collaboration, suggesting a need for more research on other trends, such as open assessment, open data, and open science. The results also suggested that future research needs to focus more on inclusive open educational practices that accommodate students with disabilities. [ABSTRACT FROM AUTHOR]

In this paper, we report the scientific experience of HELMeTO 2020, the second edition of the International Workshop on Higher Education Learning Methodologies and Technologies Online, held virtually in Bari (Italy) in September 2020 because of the COVID-19 pandemic. The call received 59 proposals from nine countries, 39 papers were accepted to the virtual workshop and 26 full papers were finally selected to be published in the proceedings. The workshop illustrated a fast-developing scenario in which the epidemic emergency accelerated the dissemination and consolidation of online learning in higher education. A specific focus of the workshop can be identified as students' learning experience, with studies on tutoring and active learning approaches, personalized solutions supported by data analysis, virtual reality and an in-depth analysis of human–computer interactions. [ABSTRACT FROM AUTHOR]

The purpose of the study is to explore students' and faculty members' responses to universities' migration from face-to-face to online instruction as a result of the coronavirus (COVID-19) crisis. To this extent, a qualitative approach was used for data collection and involved a number of qualitative methods: an open-ended question survey, focus group discussion, social media data, and university reports. Additionally, a thematic analysis was used for data analysis. The findings of the study reveal that students and faculty members were overwhelmed and stressed at the beginning, but as they started to acclimate to it, faculty members were satisfied. However, students seemed to be dissatisfied with this new approach to learning. Furthermore, faculty members and students both mentioned different challenges they had faced. The study reports on the technological tools used to mitigate the emerging challenges of both students and faculty members. Evaluating and assessing students was a main challenge for faculty members as the study analyzes the assessment and evaluation tools that they use in their online teaching. Comparative studies from Palestine and other countries are suggested for future research. [ABSTRACT FROM AUTHOR]

Many researchers have underlined the benefits of student mobility in strengthening their communication skills. Studying a foreign language and fostering knowledge about behavioural attitudes are the most common research cases. One of the major issues of mobility, by its very nature, is that it implies significant travel and accommodation costs. Virtual mobility, or Virtual Exchange (VE), can be introduced as a proactive alternative solution. This work presents an evaluation of a telecollaborative online course model organised as a VE between German and Moroccan universities. It was established to explore the benefits of integrating a VE experience by practicing some 21st-century knowledge elements as tools for the development of intercultural, language, and digital competencies from the perspective of mobility. In this paper, we present a VE model and its design, structure, and progress. Then, we evaluate this first experience to overcome some challenges that similar future experiences could face. We analyse the tools proposed in this design, the interactions between the different actors, and their feedback. The evaluative study shows the acquisition of awareness of cultural differences and the improvement of language skills through practice in addition to the development of some digital skills. [ABSTRACT FROM AUTHOR]

There is a growing body of literature that recognizes the importance of applying gamification in educational settings. This research developed an application to gamify students' homework to address the concern of the students' inability to complete their homework. This research aims to investigate students' performance in doing their homework, and reflections and perceptions of the gameful experience in gamified homework exercises. Based on the data gathered from experimental and control groups (N = 84) via learning analytics, survey, and interview, the results show a high level of satisfaction according to students' feedback. The most noticeable finding to extract from the analysis is that students can take on a persona, earn points, and experience a deeper sense of achievement through doing the gamified homework. Moreover, the students, on the whole, are likely to be intrinsically motivated whenever the homework is attributed to factors under their own control, when they consider that they have the expertise to be successful learners to achieve their desired objectives, and when they are interested in dealing with the homework for learning, not just achieving high grades. [ABSTRACT FROM AUTHOR]

Laboratory experimentation has a vital role in science education. With the potential offered by information and communication technologies for the educational domain, virtual laboratories have emerged as a valuable alternative to face-to-face, hands-on laboratories. Moreover, the possibility of virtual laboratories opens new perspectives for higher education sustainability. They are a perfect approach for training learners to understand scientific principles in many fields of science by offering them the possibility to illustrate the scientific phenomena through automated and virtual practical activities that employ computer simulation. In this work, we present the use of computer simulation combined with the JavaScript programming language for the development of a low-cost virtual laboratory integrated into an interactive learning environment based on the Moodle platform. The methodology was based on the instructional design model ADDIE (Analysis, Design, Development, Implementation, and Evaluation), which structures the development planning of online teaching resources in different stages (analysis, design, development, implementation, and evaluation). The virtual laboratory was developed by Moroccan universities, with the help of European partners, and it was implemented in the 12 science faculties in Morocco. It presents a great choice for supporting laboratory activities for learners in the first year of their bachelor's degree program. This virtual laboratory includes 12 virtual practical activities mapped to the physics curriculum, and they can be operated via the Internet on computers. The proposed virtual learning environment was evaluated by teachers and learners from the science faculties. The obtained results, together with similar findings from other studies, indicate the positive impact of the use of a virtual laboratory on learning outcomes, and support the adoption of the proposed learning environment in laboratory educational procedures as an alternative to physical laboratories. [ABSTRACT FROM AUTHOR]

Online learning has become essential in education as the spread of coronavirus 19 (COVID-19) pandemic has brought significant changes to the field. However, education should remain welcoming and supportive to all the learners as it is important to keep the students' behavioural intention in any form of learning environment. Thus, this study is significant as online learning is leading the trend of education now. Past studies revealed that the factors of performance expectancy, effort expectancy, social influence, and facilitating conditions under the unified theory of acceptance and use of technology (UTAUT) model affect learners' behavioural intention to use online learning. This study intended to identify the most significant factors that influence TESL postgraduate students' behavioural intention towards the use of online learning during the COVID-19 pandemic. It also examined the relationship amongst the four factors and postgraduate students' behavioural intention to use online learning. The participants consisted of 169 postgraduate students at a public university in Malaysia. To achieve the aim, the study utilized a survey design using a questionnaire. The results from regression analysis revealed that all of the factors have positive effects on postgraduate students' behavioural intention to use online learning. Meanwhile, performance expectancy has the greatest influence on postgraduate students' behavioural intention. Hence, this study concludes that the practicality and the usefulness of online learning should be highlighted by the authorities. [ABSTRACT FROM AUTHOR]

The COVID-19 pandemic revealed the need for new innovative methods to effectively maintain education in times of crisis and uncertainty. This study first presents the Online-Merge-Offline (OMO) learning approach, a way of learning that caters to the new needs of students and teachers in the post-COVID-19 era. OMO learning utilizes a hybrid infrastructure that combines Open Educational Practices and real-time learning spaces, both online and offline. This study then discusses the early results of a pilot experiment investigating OMO learning in China for three months from three dimensions: space design requirements, technological considerations, and pedagogical considerations. A qualitative, two-stage study focused on content analysis and a multiple-case study were carried out in the context of courses about English language learning with 30 teachers and students. The obtained findings showed that, although both teachers and students had a positive attitude towards OMO learning, they mentioned that a comprehensive set of core and functional competencies are needed—including the use of online platforms, communication skills, class management, and the effective use of resources. Additionally, the findings showed that more effort should be paid to classroom design, such as infrastructure, to efficiently support OMO learning. This study exemplifies a new approach toward the future of education to ensure sustainable education in this complex and uncertain world. [ABSTRACT FROM AUTHOR]

The purpose of Graphic Design is to transfer information about design into reality and concerns the analysis, design and representation of mechanical components and assemblies. For the correct rendering of mechanical components, this discipline requires a command of, and the ability to, manage techniques and systems for graphical representation and standardisation; 3D models in a virtual environment enable engineering students to develop graphical skills and spatial awareness. The objective of the present study is the development of an application for smart devices (mobile phones and tablets), based on the constructionist theory of learning, which will enable first year engineering degree students to acquire the technical drawing knowledge and skills necessary to render mechanical assemblies. The mobile application tested and designed in this work is called ARPAID. It is a learning tool aimed at teaching students about the representation of mechanical assemblies as part of an engineering Graphic Design course. Teaching material and a process for evaluation have been designed. A detailed description is given of a classroom activity accompanied by a tabulation and analysis of the results obtained. This mobile application, when used in a Graphic Design course, promotes a more rapid understanding of spatial relationships and problems, fosters students' learning and motivation, and develops higher order skills. Results from before and after the use of the application will be presented and do indeed show significant improvements in student performance. [ABSTRACT FROM AUTHOR]

As an emerging biomedical image processing technology, medical image segmentation has made great contributions to sustainable medical care. Now it has become an important research direction in the field of computer vision. With the rapid development of deep learning, medical image processing based on deep convolutional neural networks has become a research hotspot. This paper focuses on the research of medical image segmentation based on deep learning. First, the basic ideas and characteristics of medical image segmentation based on deep learning are introduced. By explaining its research status and summarizing the three main methods of medical image segmentation and their own limitations, the future development direction is expanded. Based on the discussion of different pathological tissues and organs, the specificity between them and their classic segmentation algorithms are summarized. Despite the great achievements of medical image segmentation in recent years, medical image segmentation based on deep learning has still encountered difficulties in research. For example, the segmentation accuracy is not high, the number of medical images in the data set is small and the resolution is low. The inaccurate segmentation results are unable to meet the actual clinical requirements. Aiming at the above problems, a comprehensive review of current medical image segmentation methods based on deep learning is provided to help researchers solve existing problems. [ABSTRACT FROM AUTHOR]

Open Educational Resources (OER) have been researched for a long time in the open education field. Researchers are now shifting their focus from resources to practices for delivering open education, an area called Open Educational Practices (OEP). However, there is little information in the related literature regarding the design of an OEP-based course or the impact of these types of courses. Therefore, this study designs a new OEP-based course at a public university for teaching family education during the COVID-19 pandemic. It also investigates its impact on learning motivation and teachers' perceptions. In this context, a practical pilot experiment using both qualitative and quantitative methods was conducted. Specifically, 36 learners participated in this experiment. The obtained findings highlight: (1) an innovative design framework for OEP-based courses that teachers can refer to in their contexts; (2) that learners had a high motivation level in terms of knowledge achievements, individual connection and engagement when taking the OEP-based course; and (3) several advantages and challenges of the OEP-based course from the teacher's and learners' perspectives. For instance, the teacher reported the fear of losing control over the learning process when applying OEP. The findings of this paper can help researchers and educators in adopting OEP in higher education especially in times of crises, as well as increase the sustainability of OEP, hence contributing to open education development. [ABSTRACT FROM AUTHOR]

Mutations in the EPM2A and EPM2B genes, encoding laforin and malin proteins respectively, are responsible for Lafora disease, a fatal form of progressive myoclonus epilepsy with autosomal recessive inheritance. Neuroimaging studies of patients with Lafora disease have shown different degrees of brain atrophy, decreased glucose brain uptake and alterations on different brain metabolites mainly in the frontal cortex, basal ganglia and cerebellum. Mice deficient for laforin and malin present many features similar to those observed in patients, including cognitive, motor, histological and epileptic hallmarks. We describe the neuroimaging features found in two mouse models of Lafora disease. We found altered volumetric values in the cerebral cortex, hippocampus, basal ganglia and cerebellum using magnetic resonance imaging (MRI). Positron emission tomography (PET) of the cerebral cortex, hippocampus and cerebellum of Epm2a−/− mice revealed abnormal glucose uptake, although no alterations in Epm2b−/− mice were observed. Magnetic resonance spectroscopy (MRS) revealed significant changes in the concentration of several brain metabolites, including N-acetylaspartate (NAA), in agreement with previously described findings in patients. These data may provide new insights into disease mechanisms that may be of value for developing new biomarkers for diagnosis, prevention and treatment of Lafora disease using animal models. [ABSTRACT FROM AUTHOR]

Higher education institutions (HEIs) have been permeated by the technological advancement that the Industrial Revolution 4.0 brings with it, and forces institutions to deal with a digital transformation in all dimensions. Applying the approaches of digital transformation to the HEI domain is an emerging field that has aroused interest during the recent past, as they allow us to describe the complex relationships between actors in a technologically supported education domain. The objective of this paper is to summarize the distinctive characteristics of the digital transformation (DT) implementation process that have taken place in HEIs. The Kitchenham protocol was conducted by authors to answer the research questions and selection criteria to retrieve the eligible papers. Nineteen papers (1980–2019) were identified in the literature as relevant and consequently analyzed in detail. The main findings show that it is indeed an emerging field, none of the found DT in HEI proposals have been developed in a holistic dimension. This situation calls for further research efforts on how HEIs can understand DT and face the current requirements that the fourth industrial revolution forced. [ABSTRACT FROM AUTHOR]

It is quite complex to adapt instruction to student needs in view of online education owing to the ensuing communication disconnection in such learning environments. Decision support schemes offer assistance by automatically gathering students' data and forwarding them to the tutor in the appropriate perspective, in order to predict their behaviour and implement some action beforehand to avert or promote the final upshot. This study shows of a decision support scheme known as u-Tutor that is centred on the similarity computation between learners in the past, and how it was used in a real-case scenario. For this case study, this tool has been utilized by two real courses comprising of 392 learners alongside academic faculty, as of 2015 to 2019. The analysis offered focuses on 3 research areas: (1) perceived usefulness, (2) usability of the tool and (3) success rate of classification. From the acquired data, it can be seen that the teaching group managed to offer excellent approximations for those learners who eventually managed to pass the course, whereas u-Tutor seemed to be an early warning for learners at risk, indicating its capacity as a tutors' supportive tool. [ABSTRACT FROM AUTHOR]

The number of students opting for online educational platforms has been on the rise in recent years. Despite the upsurge, student retention is still a challenging task, with some students recording low-performance margins on online courses. This paper aims to predict students' performance and behaviour based on their online activities on an e-learning platform. The paper will focus on the data logging history and utilise the learning management system (LMS) data set that is available on the Sakai platform. The data obtained from the LMS will be classified based on students' learning styles in the e-learning environment. This classification will help students, teachers, and other stakeholders to engage early with students who are more likely to excel in selected topics. Therefore, clustering students based on their cognitive styles and overall performance will enable better adaption of the learning materials to their learning styles. The model-building steps include data preprocessing, parameter optimisation, and attribute selection procedures. [ABSTRACT FROM AUTHOR]

The goal of this paper is to advance the understanding of the way university educators currently adopt open educational practices (OEP) by analyzing the relation between the use of open educational resources (OER) and the implementation of open teaching practices. The results are based on data collected through an online survey among 724 university educators. Depending on the actual use of OER and open teaching practices by the survey respondents, we have categorized them along a scale that goes from "novice" to "expert", and we analyzed the data to evaluate their use of OER and their adoption of open teaching practices, looking for relationships between the two phenomena. The main finding of this paper, which confirms the latest research findings from the open education community, is that a strong relationship exists between the two dimensions: The more an educator uses OER, the more he will probably adopt open teaching practices, and vice versa. These results are discussed with a view to use this virtuous circle between the use of open content and adoption of open teaching as a way to build generalized open education capacity among universities' teaching staff. [ABSTRACT FROM AUTHOR]

The topic presented will show how different kinds of sensors can help to improve our skills in learning environments. When we open the mind and let it take the control to be creative, we can think how a martial art would be improved with registered sensors, or how a person may dance with machines to improve their technique, or how you may improve your soccer kick for a penalties round. The use of sensors seems easy to imagine in these examples, but their use is not limited to these types of learning environments. Using depth cameras to detect patterns in oral presentations, or improving the assessment of agility through low cost-sensors with multimodal learning analytics, or using computing devices as sensors to measure their impact on primary and secondary students' performances are the focus of this study as well. We hope readers will find original ideas that allow them to improve and advance in their own researches. [ABSTRACT FROM AUTHOR]

The concepts of Open Educational Resources (OER) and Open Educational Practices (OEP), regarded as two pillars of the broader open education movement, have been evolving since the concept of OER was first coined in the 2012 Paris Declaration. Several research studies have been conducted to investigate the impacts of OER and OEP adoption and implementation in universities. However, most of those studies have focused on western and developed countries, and little information is known about developing countries, especially Asian ones. Particularly, China was one of the first Asian countries to adopt open education and its related strategies following the MIT OpenCourseWare conference in Beijing in 2003. This study conducts a systematic literature review to investigate the current state of the art of OER and OEP in China. The findings show that several governmental, organizational, and institutional initiatives have been launched to facilitate OER adoption in China. They also show that while several OEPs have been implemented, there is still a continuous need to work on these practices and further investigate their impacts on learning outcomes and behaviors, as no current reviewed study has done so. Finally, a generic framework of OER and OEP challenges is presented along with recommendations to further enhance the adoption of OER and OEP in China. [ABSTRACT FROM AUTHOR]

Physics is considered a tough academic subject by learners. To leverage engagement in the learning of this STEM area, teachers try to come up with creative ideas about the design of their classroom lessons. Sports-related activities can foster intuitive knowledge about physics (gravity, speed, acceleration, etc.). In this context, martial arts also provide a novel way of visualizing these ideas when performing the predefined motions needed to master the associated techniques. The recent availability of cheap monitoring hardware (accelerometers, cameras, etc.) allows an easy tracking of the aforementioned movements, which in the case of aikido, usually involve genuine circular motions. In this paper, we begin by reporting a user study among high-school students showing that the physics concept of moment of inertia can be understood by watching live exhibitions of specific aikido techniques. Based on these findings, we later present Phy + Aik, a tool for educators that enables the production of innovative visual educational material consisting of high-quality videos (and live demonstrations) synchronized/tagged with the inertial data collected by sensors and visual tracking devices. We think that a similar approach, where sensors are automatically registered within an intelligent framework, can be explored to teach other difficult-to-learn STEM concepts. [ABSTRACT FROM AUTHOR]

Higher education institutions (HEIs) have been permeated by the technological advancement that the Industrial Revolution 4.0 brings with it, and forces institutions to deal with a digital transformation in all dimensions. Applying the approaches of digital transformation to the HEI domain is an emerging field that has aroused interest during the recent past, as they allow us to describe the complex relationships between actors in a technologically supported education domain. The objective of this paper is to summarize the distinctive characteristics of the digital transformation (DT) implementation process that have taken place in HEIs. The Kitchenham protocol was conducted by authors to answer the research questions and selection criteria to retrieve the eligible papers. Nineteen papers (1980-2019) were identified in the literature as relevant and consequently analyzed in detail. The main findings show that it is indeed an emerging field, none of the found DT in HEI proposals have been developed in a holistic dimension. This situation calls for further research efforts on how HEIs can understand DT and face the current requirements that the fourth industrial revolution forced.