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Introduction and Aim: Simultaneous positron emission tomography/magnetic resonance imaging (PET-MRI) combines the high sensitivity of PET with the high specificity of MRI and is a tool for the assessment of gastroenteropancreatic neuroendocrine neoplasms (G-NENs). However, it remains poorly evaluated with no clear recommendations in current guidelines. Thus, we evaluated the prognostic impact of PET-MRI in G-NEN patients., Methods: From June 2017 to December 2021, 71 G-NEN patients underwent whole-body PET-MRI for staging and/or follow-up purposes. A whole-body emission scan with 18 F-6-fluoro-L-dihydroxyphenylalanine ( 18 FDOPA, n = 30), 18 F-fluoro-2-deoxy-D-glucose ( 18 FDG, n = 21), or 68 Ga-(DOTA(0)-Phe(1)-Tyr(3))-octreotide ( 68 Ga-DOTATOC, n = 20) with the simultaneous acquisition of a T1-Dixon sequence and diffusion-weighed imaging (DWI), followed by a dedicated step of MRI sequences with a Gadolinium contrast was performed. The patients underwent PET-MRI every 6-12 months during the follow-up period until death. Over this period, 50 patients with two or more PET-MRI were evaluated., Results: The mean age was 61 [extremes, 31-92] years. At the baseline, PET-MRI provided new information in 12 cases (17%) as compared to conventional imaging: there were more metastases in eight, an undescribed location (myocardia) in two, and an unknown primary location in two cases. G grading at the baseline influenced overall survival. During the follow-up (7-381 months, mean 194), clinical and therapy managements were influenced by PET-MRI in three (6%) patients due to new metastases findings when neither overall, nor disease-free survivals in these two subgroups ( n = 12 vs. n = 59), were different., Conclusion: Our study suggests that using PET/MRI with the appropriate radiotracer improves the diagnostic performance with no benefit on survival. Further studies are warranted to evaluate the cost-effectiveness of this procedure.

Background: The increasing prevalence of comorbidities worldwide has spurred the need for time-effective pre-hospital emergency medical services (EMS). Some pre-hospital emergency calls requesting EMS result in patient non-conveyance. Decisions for non-conveyance are sometimes driven by the patient or the clinician, which may jeopardize the patients' healthcare outcomes. This study aimed to explore the distribution and determinants of patient non-conveyance to hospitals in a Middle Eastern national Ambulance Service that promotes the transportation of all emergency call patients and does not adopt clinician-based non-conveyance decision., Methods: Using R Language, descriptive, bivariate, and binary logistic regression analyses were conducted for 334,392 multi-national patient non-conveyance emergency calls from June 2018 to July 2022, from a total of 1,030,228 calls to which a response unit was dispatched., Results: After data pre-processing, 237,862 cases of patient non-conveyance to hospital were retained, with a monthly average of 41.96% ( n = 8799) of the emergency service demands and a standard deviation of 5.49% ( n = 2040.63). They predominantly involved South Asians (29.36%, n = 69,849); 64.50% ( n = 153,427) were of the age category from 14 to 44 years; 61.22% ( n = 145,610) were male; 74.59% ( n = 177,424) from the urban setting; and 71.28% ( n = 169,552) had received on-scene treatment. Binary logistic regression with full variables and backward methods identified the final models of the determinants of patient non-conveyance decisions with an Akaike information criterion prediction estimator, respectively, of (250,200) and (250,169), indicating no significant difference between both models (Chi-square test; p -value = 0.63)., Conclusions: Despite exercising a cautious protocol by encouraging patient transportation to hospital, patient non-conveyance seems to be a problem in the healthcare system that strains the pre-hospital medical response teams' resources. Policies and regulations should be adopted to encourage individuals to access other primary care centers when required rather than draining emergency services for non-emergency situations.

This study presents an experimental and numerical investigation into the efficiency of a two-stage heat recovery-storage system for reducing the thermal energy losses in the industry. The system is designed to recover and store waste thermal energy from residual fluids using heat pipes for recovery and an environmentally friendly phase change material for heat storage. Experimental investigation was conducted using water as the primary agent and varying the temperature between 60 °C, 65 °C, and 70 °C at a constant flow rate of 24 L/min. The secondary agent, also water, was used at an initial temperature of 10 °C and the flow rate was varied between 1 L/min, 2 L/min, and 3 L/min. The results show that the system had a peak efficiency of 78.1% and was able to recover a significant amount of thermal energy. This study demonstrates the potential of this system to reduce the thermal energy losses in the industry and highlight the importance of further research and development in this field, as the industry is responsible for approximately 14% of the total thermal energy losses and finding efficient ways to recover and store waste thermal energy is crucial to achieving sustainable energy consumption.

The aim of the study is to develop a system for converting, accumulating, and delivering solar energy that is based on the development of an innovative solar panel with heat pipes and a heat storage wall, for the construction of passive structures. The novel aspect of this experiment is the utilization of concrete walls that have different recyclable materials added to their structure in various proportions. The solar energy from the sunny façades is transformed by this system into thermal energy, which is then transferred by integrated heat pipes in a massive element with high thermal inertia. Using insulated shutters, thermal energy can be stored during the day and released at night to keep the room at a comfortable temperature. In order to integrate the modules into the solar recovery system, four concrete samples were cast with a blend of standard and waste aggregates. Four heat fluxes of 100 W/m 2 , 150 W/m 2 , 200 W/m 2 , and 250 W/m 2 were applied to each global system. Thermal imaging data and numerical simulations both supported the findings of temperature sensors. The most effective mixture, fly ash and chopped PET, delivered temperatures that were, on average, 3.3% higher at the end of the charging cycle than those measured for the control sample. The discharging cycle of the concrete block with fly ash and sawdust was the most effective, with an average temperature loss of 5.0 °C as compared to 5.5 °C for the control sample, on average.

The continuous growth of the concrete industry requires an increased quantity of cement and natural aggregates year after year, and it is responsible for a major part of the global CO 2 emissions. These aspects led to rigorous research for suitable raw materials. Taking into account that these raw materials must have a sustainable character and also a low impact on environmental pollution, the replacement of the conventional components of concrete by residual waste can lead to these targets. This paper's aim is to analyze the density, compressive strength and the thermal conductivity of nine concrete compositions with various rates of waste: four mixes with 10%, 20%, 40% and 60% chopped PET bottles aggregates and 10% fly ash as cement partial substitution; a mix with 60% waste polystyrene of 4-8 mm and 10% fly ash; a mix with 20% waste polystyrene of 4-8 mm, 10% waste polystyrene of 0-4 mm and 10% fly ash; a mix with 50% waste polystyrene of 4-8 mm, 20% waste polystyrene of 0-4 mm and 20% fly ash two mixes with 10% fly ash and 10% and 40% waste sawdust, respectively. Using 60% PET aggregates, 60% polystyrene granules of 4-8 mm, or 20% polystyrene of 0-4 mm together with 50% polystyrene of 4-8 mm led to the obtainment of lightweight concrete, with a density lower than 2000 kg/m 3 . These mixes also registered the best results from a thermal conductivity point of view, after the concrete mix with 40% saw dust. Regarding compressive strength, the mix with 10% PET obtained a result very close to the reference mix, while those with 20% PET, 40% PET, 30% polystyrene, and 10% saw dust, respectively, registered values between 22 MPa and 25 MPa, values appropriate for structural uses.