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Soil moisture (SM) retrieved from satellite and spaceborn sensors provides useful parameters for earth system models (ESMs). The Climate Change Initiative (CCI) SM products released by the European Space Agency have been widely used in many humid/semi-humid climatic regions due to their relatively long-term record. However, the performance of these products in cold and arid regions, such as the Qinghai-Tibetan Plateau (QTP), is largely unknown, necessitating urgent evaluation and calibration in these areas. In this work, we evaluated the reliability and improved the accuracy of the active-passive combined CCI products (CCI-C) using in-situ measured SM contents (SMC) under different underlying surface conditions. First, some conventional models were used to investigate the relationship between the CCI-C and the in-situ observed SMC, yielding similar fitting performances. Next, the random forest method and multiple linear regression were used to contrast the conventional models to calibrate and validate the CCI-C SM product based on the in-situ observed SMC, and the random forest method was found to have the highest accuracy. However, calibration of the CCI-C SM data with the best-performed random forest method based on different spatial zonation methods, e.g., by climate, topography, land cover, and vegetation, resulted in distinct spatial patterns of SM. Compared to a widely-used satellite SM product, namely the Soil Moisture Active Passive (SMAP) SM dataset, the calibrated CCI-C SM data based on climatic and vegetation zonation were larger but had similar spatial patterns. This study also points to the value of the calibrated CCI-C SM product to support land surface studies on the QTP. [ABSTRACT FROM AUTHOR]