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An arterial prosthesis prepared from human placental arteries, diameter 1.0 mm, length 20 mm, was evaluated after implantation into the infrarenal region of the aorta of the rat. The permeability rate after one year (70%) compares favorably with results after fresh arterial autografts. Histology showed that the prosthesis acted as a matrix colonizable by the tissues of the recipient. The internal surface of the tube was covered by a tissular layer in which fibrillary elements suggestive of elastic fibers were developing.

An experimental study of a micro-arterial prosthesis prepared from biological materials was carried out in the rat. The results obtained after two months were analysed in terms of permeability of the biochemical constituants of the vessel and of the neighbouring scar tissue, and endothelial healing. These studies showed the association with a process of proteolysis of the implanted vessel, of a process of reconstruction. They show moreover the quality of the endothelial scar on the internal surface of the vessel.