1. [Multidrug-resistant tuberculosis (MDR-TB) in a black African carceral area: Experience of Mali].
- Author
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Toloba Y, Ouattara K, Soumaré D, Kanouté T, Berthé G, Baya B, Konaté B, Keita M, Diarra B, Cissé A, Camara FS, and Diallo S
- Subjects
- Adolescent, Adult, Black or African American, Humans, Incidence, Male, Mali epidemiology, Middle Aged, Mycobacterium tuberculosis isolation & purification, Prisons statistics & numerical data, Prospective Studies, Risk Factors, Tuberculosis, Multidrug-Resistant drug therapy, Tuberculosis, Pulmonary drug therapy, Young Adult, Antitubercular Agents therapeutic use, Tuberculosis, Multidrug-Resistant ethnology, Tuberculosis, Pulmonary ethnology
- Abstract
Introduction: Prison constitutes a risk factor for the emergence of multi-drug resistance of tuberculosis (MDR-TB). The aim of this work was to study MDR-TB in a black African carceral center., Material and Methods: Prospective study from January to December 2016 at the central house of arrest for men, Bamako. The study population was composed of tuberculous detainee. The suspicion of MDR-TB was done in any tuberculosis case remained positive in the second month of first-line treatment or in contact with an MDR-TB case., Result: Among 1622 detainee, 21 cases of pulmonary tuberculosis were notified (1.29%), with an annual incidence of 13 cases/1000 detainee, they were 16 cases of SP-PTB (microscopy smear positive tuberculosis) and five cases of microscopy smear negative tuberculosis. The mean age was 28±7 years, extremes of 18 and 46 years. A negative association was found between the notion of smoking and occupation in the occurrence of tuberculosis (OR=0.036, [95% CI: 0.03-0.04], P=0.03. Among the 21 tuberculosis cases notified, one confirmed case of MDR-TB was detected (4.7%). In the first semester of 2016 cohort, we notified a cure rate of 87.5% (7/8 SP-PTB cases), and the confirmed MDR-TB case on treatment (21-month regimen), evolution enameled of pulmonary and hearing sequelae at seven months treatment., Conclusion: It was the first case of MDR-TB detected in a prison in Mali. Late diagnosis, evolution is enameled of sequelae and side effects., (Copyright © 2017 Elsevier Masson SAS. All rights reserved.)
- Published
- 2018
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