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Your search keyword '"Steven J, Yakubov"' showing total 2 results
Start Over Author "Steven J, Yakubov" Publisher massachusetts medical society
2 results on '"Steven J, Yakubov"'

1. Transcatheter Aortic-Valve Replacement with a Self-Expanding Valve in Low-Risk Patients

Author

Joshua Rovin, Michael J. Reardon, David H. Adams, Judah Askew, P.S. Teirstein, Tanvir Bajwa, John Heiser, G. Michael Deeb, Newell Robinson, Thomas G. Gleason, Antony Walton, Paul Sorajja, Neal S. Kleiman, Hemal Gada, John K. Forrest, Jae K. Oh, Basel Ramlawi, Mubashir Mumtaz, Michael J. Boulware, Jon R. Resar, George Petrossian, Stanley Chetcuti, Andrew S. Mugglin, Nicolo Piazza, George L. Zorn, Steven J. Yakubov, Daniel O'Hair, William Merhi, Didier Tchetche, Hongyan Qiao, and Jeffrey J. Popma

Subjects
Aortic valve, medicine.medical_specialty, Transcatheter aortic, business.industry, medicine.medical_treatment, Atrial fibrillation, General Medicine, 030204 cardiovascular system & hematology, medicine.disease, Surgery, 03 medical and health sciences, Stenosis, 0302 clinical medicine, medicine.anatomical_structure, Valve replacement, Aortic valve stenosis, cardiovascular system, medicine, In patient, 030212 general & internal medicine, business, Stroke
Abstract

Background Transcatheter aortic-valve replacement (TAVR) is an alternative to surgery in patients with severe aortic stenosis who are at increased risk for death from surgery; less is know...

Published
2019
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2. Transcatheter Aortic-Valve Replacement with a Self-Expanding Prosthesis

Author

David H, Adams, Jeffrey J, Popma, Michael J, Reardon, Steven J, Yakubov, Joseph S, Coselli, G Michael, Deeb, Thomas G, Gleason, Maurice, Buchbinder, James, Hermiller, Neal S, Kleiman, Stan, Chetcuti, John, Heiser, William, Merhi, George, Zorn, Peter, Tadros, Newell, Robinson, George, Petrossian, G Chad, Hughes, J Kevin, Harrison, John, Conte, Brijeshwar, Maini, Mubashir, Mumtaz, Sharla, Chenoweth, Jae K, Oh, and Jean-Claude, Laborde

Subjects
Male, Cardiac Catheterization, medicine.medical_specialty, medicine.medical_treatment, Kaplan-Meier Estimate, Prosthesis Design, law.invention, Postoperative Complications, Randomized controlled trial, Valve replacement, Risk Factors, law, medicine, Risk of mortality, Humans, Stroke, Survival rate, Aged, Cardiac catheterization, Aged, 80 and over, Bioprosthesis, business.industry, Aortic Valve Stenosis, General Medicine, medicine.disease, Surgery, Survival Rate, Stenosis, Aortic Valve, Heart Valve Prosthesis, Female, Risk assessment, business
Abstract

BACKGROUND We compared transcatheter aortic-valve replacement (TAVR), using a self-expanding transcatheter aortic-valve bioprosthesis, with surgical aortic-valve replacement in patients with severe aortic stenosis and an increased risk of death during surgery. METHODS We recruited patients with severe aortic stenosis who were at increased surgical risk as determined by the heart team at each study center. Risk assessment included the Society of Thoracic Surgeons Predictor Risk of Mortality estimate and consideration of other key risk factors. Eligible patients were randomly assigned in a 1:1 ratio to TAVR with the self-expanding transcatheter valve (TAVR group) or to surgical aortic-valve replacement (surgical group). The primary end point was the rate of death from any cause at 1 year, evaluated with the use of both noninferiority and superiority testing. RESULTS A total of 795 patients underwent randomization at 45 centers in the United States. In the as-treated analysis, the rate of death from any cause at 1 year was significantly lower in the TAVR group than in the surgical group (14.2% vs. 19.1%), with an absolute reduction in risk of 4.9 percentage points (upper boundary of the 95% confidence interval, −0.4; P

Published
2014
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