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The study attempts to evaluate the efficacy and safety of endobronchial valves as a form of treatment for patients with advanced emphysema. The results indicate that such a form of treatment did result in modest improvements in lung function; however, also resulted in more frequent chronic obstructive pulmonary disease (COPD), pneumonia and hemoptysis following implantation.

The proposed mechanisms considered to lead to chronic obstructive pulmonary disease (COPD) are reviewed by analyzing them in three steps that may contribute to its development. The emerging evidence that COPD is aggravated by T-cell-mediated inflammation, which is considered an autoimmunity reaction to smoke-filled lung injury, is also analyzed.

The article discusses the new developments and pathogenesis of infections in chronic obstructive pulmonary disease (COPD). Infection has been found to be the main cause of exacerbations in COPD and antibiotics has been found to be quite effective in the treatment of these exacerbations.

Chronic Obstructive Pulmonary Disease is a syndrome of progressive airflow limitation caused by chronic inflammation of the airways and lung parenchyma. The major goals include smoking cessation, symptom relief, improvement in physiological function and limitation of complications.

Results of a study to evaluate the efficacy and safety of endobronchial valves as a form of treatment for patients with advanced emphysema have revealed that such a form of treatment did result in modest improvements in lung function; however, also resulted in more frequent chronic obstructive pulmonary disease (COPD), pneumonia and hemoptysis following implantation. Further testing is essential before recommending the routine use of such valves in patients with COPD.