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Your search keyword '"Holmes, King K."' showing total 39 results
Start Over Author "Holmes, King K." Publisher massachusetts medical society
39 results on '"Holmes, King K."'

1. Condom use and the risk of genital human papillomavirus infection in young women

Author

Winer, Rachel L., Hughes, James P., Qinghua Feng, O'Reilly, Sandra, Kiviat, Nancy B., Holmes, King K., and Koutsky, Laura A.

Subjects
Papillomavirus infections -- Risk factors, Condoms -- Usage, Women -- Health aspects
Abstract

Studies were conducted to evaluate whether the use of male condoms reduces the risk of male-to-female transmission of human papillomavirus (HPV) infection. The findings indicate that among newly sexually active women, consistent condom use by their partners appears to reduce the risk of cervical and vulvovaginal HPV infection.

Published
2006

2. Effect of expedited treatment of sex partners on recurrent or persistent gonorrhea or chlamydial infection

Author

Golden, Matthew R., Whittington, William L.H., Handsfield, H. Hunter, Hughes, James P., Stamm, Walter E., Hogben, Matthew, Clark, Agnes, Malinski, Cheryl, Helmers, Jennifer R. L., Holmes, King K., and Thomas, Katherine K.

Subjects
Chlamydia infections -- Risk factors, Chlamydia infections -- Research, Gonorrhea -- Risk factors, Gonorrhea -- Research
Abstract

Women and heterosexual men are randomly assigned with gonorrhea or chlamydial infection to have their partners receive expedited treatment or standard referral. It is found that expedited treatment of sex partners reduces the rates of persistent or recurrent gonorrhea or chlamydial infection.

Published
2005

4. Prevention of pelvic inflammatory disease by screening for cervical chlamydial infection

Author

Scholes, Delia, Stergachis, Andy, Heidrich, Fred E., Andrilla, Holly, Holmes, King K., and Stamm, Walter E.

Subjects
Chlamydia infections -- Diagnosis, Pelvic inflammatory disease -- Risk factors, Medical screening -- Evaluation
Abstract

Screening women who are at high risk of sexually transmitted diseases and treating them could reduce the incidence of pelvic inflammatory disease. There are an estimated 4 million cases of chlamydial infections in the US each year, making this the most common sexually transmitted disease. This infection can travel up the genital tract, causing pelvic inflammatory disease. Researchers identified 2,607 women in an HMO who had a high risk of chlamydial infections. The risk factors included young age, black race, two or more sex partners in the past and douching. A total of 1,009 were assigned to be screened for chlamydial infections and 1,598 were assigned to usual care. A total of 645 women in the screening group were actually tested for Chlamydia and 44 tested positive. All 44 received treatment for chlamydial infections. After a 12-month follow-up, 9 women in the screening group had developed pelvic inflammatory disease compared to 33 of the women who were not screened. This represents a reduction of 56% in the incidence of pelvic inflammatory disease.

Published
1996

5. A cohort study of the risk of cervical intraepithelial neoplasia grade 2 or 3 in relation to papillomavirus infection

Author

Koutsky, Laura A., Holmes, King K., Critchlow, Cathy W., Stevens, Claire E., Paavonen, Jorma, Beckmann, Anna Marie, DeRouen, Timothy A., Galloway, Denise A., Vernon, Debra, and Kiviat, Nancy B.

Subjects
Cervical cancer -- Risk factors, Papillomavirus infections -- Complications
Abstract

Women with human papillomavirus (HPV) infections may have a higher risk of developing cervical intraepithelial neoplasia, or precancerous cervical lesions, than other women. Precancerous cervical lesions are changes in the cervix that precede the development of cervical cancer. Among 241 women who were screened for sexually transmitted diseases, 110 were diagnosed with an HPV infection. Twenty-eight percent of the women who developed a HPV infection were diagnosed with grade two or grade three precancerous cervical lesions within two years of HPV detection, compared with 3% of those without an HPV infection. Women who were infected with HPV type 16 or type 18 had a higher risk of developing precancerous cervical lesions than those with infections caused by other HPV types. Women who have intercourse for the first time at a younger age may also have a higher risk of developing precancerous cervical lesions than those who have first intercourse at an older age.

Published
1992

6. Underdiagnosis of genital herpes by current clinical and viral-isolation procedures

Author

Koutsky, Laura A., Stevens, Claire E., Holmes, King K., Ashley, Rhoda L., Kiviat, Nancy B., Critchlow, Cathy W., and Corey, Lawrence

Subjects
Herpes genitalis -- Diagnosis, Women -- Diseases
Abstract

A blood test to detect antibodies against herpes simplex virus (HSV) may increase the number of women diagnosed with genital or anal herpes. Many women infected with HSV, a virus that is sexually transmitted, are not diagnosed by a physical examination or attempts to grow the virus from samples taken from the genitals. Of 779 women who had a physical examination, a Pap smear and a blood test for antibodies against HSV, 363 (47%) were diagnosed with HSV type 2, and 9 (one percent) with HSV type 1. Eighty-two women (22%) who were diagnosed with HSV infection had symptoms, and 14 women (four percent) had viral shedding without symptoms. Sixty women had symptoms in the past, and 216 had antibodies against HSV-2 without viral shedding or symptoms. The most sensitive method for diagnosis of a first episode of HSV infection was growth of the virus from a sample taken from the genitals. But the most sensitive method for diagnosis of a recurrent episode of HSV-2 infection was a blood test for antibodies against the virus.

Published
1992

7. Sexually transmitted diseases in victims of rape

Author

Jenny, Carole, Hooton, Thomas M., Bowers, Ann, Copass, Michael K., Krieger, John N., Hillier, Sharon L., Kiviat, Nancy, Corey, Lawrence, Stamm, Walter E., and Holmes, King K.

Subjects
Rape victims -- Diseases, Sexually transmitted diseases -- Statistics
Abstract

The frequency with which women acquire a sexually transmitted disease (STD) as a consequence of rape is not known. Studies on this subject have examined women at many different intervals after the assault and it has been impossible to determine whether an infection began when the rape occurred. To better address this issue, 204 girls and women underwent gynecological examinations 72 hours or less after being raped, and 109 of them returned two weeks later for a follow-up examination. The assumption was made that an STD present on follow-up that had not been diagnosed previously was a consequence of the assault. Tests were performed to detect gonorrhea, chlamydia, trichomoniasis, herpes simplex virus, treponema pallidum, bacterial vaginosis, and human immunodeficiency virus type 1. Results showed that 28 percent of the patients had one STD at the initial examination, nine percent had two, and six percent had three or more. In all, 56 percent had at least one sexually transmitted disease at one of the exams. The frequency of new infections present at follow-up were: gonorrhea, four percent; chlamydia, two percent; trichomoniasis, 12 percent; and bacterial vaginosis, 19 percent. The risk of acquiring a vaginal infection was greater than the risk of acquiring a cervical infection. These results may not be representative of all rape victims initially examined, since only 109/204 returned for follow-up. It appears that rape victims have a high rate of STD before the rape and that they have a substantial risk of acquiring such diseases as a consequence of the assault. (Consumer Summary produced by Reliance Medical Information, Inc.)

Published
1990

8. Therapy for human immunodeficiency virus infection - what have we learned?

Author

Corey, Lawrence and Holmes, King K.

Subjects
HIV infection -- Drug therapy, Drug therapy, Combination -- Evaluation, Zidovudine -- Evaluation, Didanosine -- Evaluation, Zalcitabine -- Evaluation
Abstract

Recent studies show that combination drug therapy may prolong the lives of AIDS patients but many will not be able to afford the treatment. Three 1996 studies evaluated zidovudine in combination with two other nucleoside inhibitors, didanosine and zalcitabine. In two studies, combination therapy prolonged survival when compared to zidovudine alone. However, the remaining study showed no difference in survival. It is possible that the groups of patients studied differed in the severity of disease. Nevertheless, there are now 7 reverse transcriptase inhibitors and 3 protease inhibitors to treat HIV infection.

Published
1996

14. Chlamydia trachomatisProctitis

Author

Quinn, Thomas C., primary, Goodell, Steven E., additional, Mkrtichian, Emmanuel, additional, Schuffler, Michael D., additional, Wang, San-Pin, additional, Stamm, Walter E., additional, and Holmes, King K., additional

Published
1981
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19. Asymptomatic Gonorrhea in Men

Author

Handsfield, H. Hunter, primary, Lipman, Timothy O., additional, Harnisch, James P., additional, Tronca, Evelyn, additional, and Holmes, King K., additional

Published
1974
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23. Polymicrobial Etiology of Acute Pelvic Inflammatory Disease

Author

Eschenbach, David A., primary, Buchanan, Thomas M., additional, Pollock, Helen M., additional, Forsyth, Patricia S., additional, Alexander, E. Russell, additional, Lin, Juey-shin, additional, Wang, San-pin, additional, Wentworth, Berttina B., additional, McCormack, William M., additional, and Holmes, King K., additional

Published
1975
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27. AIDS Virus Infection in Nairobi Prostitutes

Author

Kreiss, Joan K., primary, Koech, Davy, additional, Plummer, Francis A., additional, Holmes, King K., additional, Lightfoote, Marilyn, additional, Piot, Peter, additional, Ronald, Allan R., additional, Ndinya-Achola, J.O., additional, D'Costa, Lourdes J., additional, Roberts, Pacita, additional, Ngugi, Elizabeth N., additional, and Quinn, Thomas C., additional

Published
1986
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28. Etiology of Nongonococcal Urethritis

Author

Holmes, King K., primary, Handsfield, H. Hunter, additional, Wang, San Pin, additional, Wentworth, Berttina B., additional, Turck, Marvin, additional, Anderson, Joanne B., additional, and Alexander, E. Russell, additional

Published
1975
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35. Nonspecific Vaginitis

Author

Pheifer, Terrence A., primary, Forsyth, Patricia S., additional, Durfee, Marcia A., additional, Pollock, Helen M., additional, and Holmes, King K., additional

Published
1978
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