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Background: Partial nephrectomy (PN) is the standard of treatment in patients with cT1 renal tumors. Current guidelines recommend PN as a standard of treatment in patients with cT1 renal tumors. However, the commonly accepted criteria for which surgical outcomes are evaluated both functionally and oncologically are not yet clear. The aim of this study was to evaluate compounding factors that affect the operative and functional outcomes for laparoscopic partial nephrectomy (LPN) in patients with cT1 renal tumors. Methods: This study was registered at NCT04213157 for patients who underwent LPN with the diagnosis of clinical T1 renal tumors. Between November 2009 and August 2018, 292 patients were included in the study. The patients were allocated into two groups according to the tumor size: T1a (n = 215) and T1b (n = 77). Demographic features, clinical tumor characteristics, and intraoperative and postoperative outcomes were analyzed. A negative surgical margin, warm ischemia time of <20 minutes, and no postoperative major complications were accepted to achieve the trifecta outcomes. Pentafecta was defined as trifecta criteria plus >90% preservation of baseline renal function (RF) and no stage upgrade of chronic kidney disease at 12 months after surgery. Univariate and multivariate analyses were used to identify factors predicting trifecta and pentafecta. Results: Preoperative variables including age, gender, and baseline RF were similar between the two groups. The warm ischemia time was 13.4 vs 15.9 minutes (P = 0.001). The positive margin rate was 0.9% vs 2.6% (P = 0.284), and the major complication rate was 3.3% vs 2.6% (P = 0.548). The achievement of the trifecta rate was 88.4% vs 75.3% (P = 0.006) and pentafecta rate was 72.6% vs 42.9% (P = 0.001). Multivariate analysis showed that tumor complexity, baseline RF, and diabetes mellitus are independent predictors of achieving pentafecta outcomes. Conclusion: LPN is an effective and reliable method for renal tumors even in T1b with satisfying surgical and functional outcomes. [ABSTRACT FROM AUTHOR]

Background: A double-pigtail ureteral stent (DPUS) can cause untoward symptoms, such as urgency, frequency, urinary incontinence, hematuria, and body pain that are bothersome to patient's quality of life (QoL). By reducing the quantity of material in the bladder, it could be reasonable to decrease stent-related symptoms (SRSs). We aimed to evaluate the tolerability of single pigtail suture stent (SPSS) with a validated questionnaire after uncomplicated retrograde semirigid ureteroscopic lithotripsy (URSL). Materials and Methods: A total of 130 patients who underwent ureteral stent placement after URSL for unilateral symptomatic ureteral stones with <15 mm diameter were randomized prospectively into two groups. Polyurethane ureteral stent (6 Fr, 24 or 26 cm) was placed in all patients, which was removed postoperatively with a mean of 14 days. There were 65 patients in both groups. All subjects completed the ureteral stent symptoms questionnaire (USSQ), which explores the SRSs. The questionnaires were conducted on the day of stent removal (at week 2) with the stent in situ and 4 weeks after removal (at week 6, poststent). The severity of SRSs and QoL were compared between the two groups. Results: SPSS was associated with perfect effect on all domains of USSQ, except from sexual and general health index scores. Pain index scores, visual analog scores (VAS), and analgesic requirements in SPSS group were found significantly low compared with those in the DPUS group. The QoL scores were significantly better in patients indwelling SPSS. Conclusion: SPSS is a potentially beneficial option to minimize ureteral SRSs after uncomplicated URSL. [ABSTRACT FROM AUTHOR]

Background: Considering the increase in a number of vascular complications, right laparoscopic donor nephrectomy is less preferred due to achieving not only shorter renal vein but also longer renal artery. However, recent studies have indicated that the side of the surgery would not affect the outcomes. Aim: The aim of this study is to evaluate the outcomes and strategies to increase the safety of pure retroperitoneoscopic donor nephrectomy (RDN). Methods: We analyzed the prospectively collected medical records of 158 kidney donors who underwent RDN from January 2010 to August 2018. The patients were divided into two groups based on their side of surgery. Right- and left-sided RDNs were compared in terms of demographics, intraoperative, and postoperative data, including the development of incisional hernia (IH). The outcomes of the recipients were also evaluated. Results: Right RDN was performed in 40 (25.3%) and left RDN was performed in 118 (74.7%) donors. Operation time (P = .593), warm ischemia time (P = .271), blood loss (P = .787), and length of hospital stay (P = .908) were statistically similar in right and left RDN groups. Intraoperative and postoperative complications were statistically showed no difference between right and left RDNs. No IH was observed in any group. One-year and five-year patient survival and graft survival rates were 100% versus 97% (P = .299) and 100% versus 95% (P = .126) on both sides, respectively. Conclusion: Right RDN is an effective and safe method as on the left side. RDN has an additional advantage in the absence of IH. Experience with other retroperitoneoscopic urological interventions may have had a positive effect on the outcomes of pure RDN. [ABSTRACT FROM AUTHOR]