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Multispecialist teleconsultation systems can be particularly useful in obtaining a second opinion from remote medical specialists. In this paper, a multispecialist teleconsultation (MST) system was designed by using multiple unicasting to enable operability over the existing Internet infrastructure and the support of reliable data transmission. The MST was tested over Asynchronous Digital Subscriber Line (ADSL), Very high speed Digital Subscriber Line (VDSL), Wireless Local Area Network (WLAN), and the hospital Local Area Network (LAN) to demonstrate the operability of the designed system over popularly deployed networks that together make up the current Internet. Also, subjective evaluation using induced delay and low quality video coding of sample brain surgery testing videos and two cases of clinical experimentations demonstrated the limiting factors of the MST in terms of quality and delay differences as well as the feasibility of the MST in a real clinical setting. [ABSTRACT FROM AUTHOR]