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1. A2-1: Longitudinal eGFR, eGFR Slope, and Cardiovascular Events Among Adults with CKD

Author

Joseph B. Leader, H. Lester Kirchner, Robert M. Perkins, and Xiaoqin Tang

Subjects
Community and Home Care, Cardiovascular event, Oncology, medicine.medical_specialty, Then test, business.industry, Internal medicine, medicine, Linear model, Selected Abstracts-HMORN 2014: Chronic Conditions/Diabetes/Obesity, General Medicine, Bioinformatics, business
Abstract

Background/Aims Single time-point GFR estimates are used for risk prognostication among those with CKD. Various applications of longitudinal eGFR using linear models, including time-independent slope and variability, have been shown to independently predict cardiovascular events. We wished to extend these applications by modeling longitudinal eGFR–forming estimates of current eGFR value and time-dependent eGFR slope at any point in time–and then test the independent association with cardiovascular event risk in an adjusted, joint longitudinal-survival model.

Published
2014

2. PS2-22: Geisinger Health System’s Clinical Interventions for Preventing Pediatric Obesity - Infancy through School-age

Author

Jennifer S Williams, Leann L. Birch, Xiaowei Yan, Joseph B. Leader, Rebecca Stametz, William Cochran, Gregory J. Welk, Gloria Gerrity, Jonathan D. Darer, Megan Mariotti, and Lisa Bailey-Davis

Subjects
Community and Home Care, Obesity prevention, medicine.medical_specialty, Pediatrics, School age child, business.industry, Psychological intervention, Alternative medicine, Clinical settings, General Medicine, medicine.disease, Obesity, Childhood obesity, Family medicine, Selected Abstracts-HMORN 2014: Child Health, medicine, business, Healthcare system
Abstract

Background/Aims Childhood obesity remains a priority issue for the nation and health systems yet little is known about the effectiveness of pediatric obesity prevention interventions overall and evidence is particularly lacking with regard to prevention in clinical settings. Our aim is to discuss process steps in developing two clinical interventions to prevent obesity and their research designs to evaluate effectiveness.

Published
2014

3. C-B4-04: Overestimation of Population Level Medication Adherence: Bias in the MPR Calculation of Hypertensive Patients

Author

James M Pitcavage, H L Kirchner, Jove Graham, J.B. Jones, and Joseph B. Leader

Subjects
Community and Home Care, education.field_of_study, Pathology, medicine.medical_specialty, Population level, business.industry, Population, Medication adherence, General Medicine, Medication possession ratio, SELECTED ABSTRACTS - HMORN 2011: Health Informatics, Electronic health record, Claims data, Internal medicine, Medicine, Medical prescription, business, education
Abstract

Background/Aims The Medication Possession Ratio (MPR) is a common claims-based metric for describing medication adherence. The MPR can only be calculated for patients who fill at least 2 prescriptions. Thus, patients with

Published
2011

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