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Start Over Author "Elgemeie GE" Publisher m. dekker
2 results on '"Elgemeie GE"'

1. Synthesis and anti-HIV activity of different novel nonclassical nucleosides.

Author

Elgemeie GE, Mansour OA, and Metwally NH

Subjects
Anti-HIV Agents chemistry, Anti-HIV Agents pharmacology, Cell Line, HIV-1 physiology, Humans, Magnetic Resonance Spectroscopy, Molecular Structure, Nucleosides chemistry, Nucleosides pharmacology, Structure-Activity Relationship, Anti-HIV Agents chemical synthesis, HIV-1 drug effects, Nucleosides chemical synthesis, Virus Replication drug effects
Abstract

A series of different novel nonclassical nucleosides have been synthesised and evaluated for their inhibitory activity against human immunodeficiency virus (HIV) replication in MT-4 cells.

Published
1999
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2. A synthetic strategy to a new class of cycloalkane ring-fused pyridine nucleosides as potential anti HIV agents.

Author

Elgemeie GE, Attia AM, and Hussain BA

Subjects
Magnetic Resonance Spectroscopy, Models, Chemical, Anti-HIV Agents chemical synthesis, Cycloparaffins chemical synthesis, Drug Design, Pyridines chemical synthesis
Abstract

Condensation of cyanothioacetamide or cyanoacetamide with sodium salts of 2-formyl-1-cycloalkanones afforded the corresponding cycloalkane ring fused pyridine-2(1H)-thiones and -2-pyridones. The latter compounds served as a key intermediates for the synthesis of a new class of cycloalkane ring fused pyridine glycosides.

Published
1998
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