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Eleven patients with Hodgkin disease involving the cardiophrenic angle lymph nodes are described. Four were discovered at the time of initial staging, and the remainder represented a major site of relapse after therapy. Regression of adenopathy after chemotherapy was documented in six patients; surgical excision (three), biopsy (one) and postmortem examination confirmed the presence of recurrent disease in the remaining cases. Enlargement of cardiophrenic angle nodes was frequently overlooked on conventional chest radiography, but a rather typical appearance is readily identifiable on CT.

Over 5 years, CT of the thorax was performed on 53 patients with Hodgkin disease and mediastinal lymphadenopathy prior to the institution of therapeutic irradiation. Information obtained from CT prompted major alterations in the plan of therapy in 11 of 53 (21%) of the patients. These included changes of treatment portal size, the addition of localized boost therapy, and a revision of diagnosis.

Computed tomography of 30 patients with chordomas arising from the clivus was reviewed. All examinations demonstrated bone destruction with a soft tissue mass and varying degrees of encroachment on the adjacent brain. Other CT findings included contrast enhancement, soft tissue calcification and well defined areas of low attenuation.