1. Ocular neuromyotonia: a review of diagnosis and treatment.
- Author
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Lee SK and Lee MS
- Subjects
- Adult, Carbamazepine therapeutic use, Child, Diplopia diagnosis, Diplopia etiology, Diplopia therapy, Excipients therapeutic use, Humans, Oculomotor Muscles surgery, Isaacs Syndrome drug therapy, Isaacs Syndrome therapy, Ocular Motility Disorders diagnosis, Ocular Motility Disorders therapy
- Abstract
Purpose of Review: The current review will cover the clinical presentation, causes, epidemiology, differential diagnoses, workup, and treatment of ocular neuromyotonia (ONM) in detail., Recent Findings: While ONM largely remains a unilateral eye movement disease affecting adults with a history of sellar radiation, recent case reports highlight an expansion of this presentation to include bilateral, pediatric, and congenital cases., Summary: ONM is a rare but recognizable ocular motility disorder involving sustained contraction of the extraocular muscle, commonly resulting in intermittent diplopia. Diagnosis of ONM relies upon a thorough history and clinical exam, with particular attention to history of radiotherapy and eccentric gaze testing. Treatment with carbamazepine remains first-line therapy, although other membrane stabilizing agents and surgical interventions can be effective., (Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.)
- Published
- 2022
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