Search

Your search keyword '"Giannattasio, A"' showing total 214 results
Start Over Author "Giannattasio, A" Publisher lippincott williams & wilkins
214 results on '"Giannattasio, A"'

2. CAROTID-FEMORAL PULSE WAVE VELOCITY PROGRESSION IN HYPERTENSIVE PATIENTS IS ASSOCIATED WITH SUBSEQUENT CV OUTCOMES

Author

Maloberti, A, Rebora, P, Occhino, G, Andreano, A, Intravaia, R, Tognola, C, Toscani, G, Morelli, M, Pezzoli, S, D’Oro, L, Russo, A, Giannattasio, C, Maloberti, Alessandro, Rebora, Paola, Occhino, Giuseppe, Andreano, Anita, Intravaia, Rita Cristina My, Tognola, Chiara, Toscani, Giorgio, Morelli, Martina, Pezzoli, Stefano, D’Oro, Luca Cavalieri, Russo, Antonio, Giannattasio, Cristina, Maloberti, A, Rebora, P, Occhino, G, Andreano, A, Intravaia, R, Tognola, C, Toscani, G, Morelli, M, Pezzoli, S, D’Oro, L, Russo, A, Giannattasio, C, Maloberti, Alessandro, Rebora, Paola, Occhino, Giuseppe, Andreano, Anita, Intravaia, Rita Cristina My, Tognola, Chiara, Toscani, Giorgio, Morelli, Martina, Pezzoli, Stefano, D’Oro, Luca Cavalieri, Russo, Antonio, and Giannattasio, Cristina

Published
2024

3. EFFECT OF ANTI-PCSK9 ANTIBODIES ON ARTERY STRUCTURE AND FUNCTION: THE NIGUARDA HOSPITAL COHORT

Author

Maloberti, A, Toscani, G, Busti, A, Tognola, C, Intravaia, R, De Censi, L, Galasso, M, Daus, F, Giani, V, Gualini, E, Garofani, I, Riccio, A, Biolcati, M, Fabbri, S, Algeri, M, Merlini, P, Giannattasio, C, Morelli, M, Maloberti, Alessandro, Toscani, Giorgio, Busti, Andrea, Tognola, Chiara, Intravaia, Rita Cristina Mi, De Censi, Lorenzo, Galasso, Michele, Daus, Franesca, Giani, Valentina, Gualini, Elena, Garofani, Ilaria, Riccio, Alfonso, Biolcati, Marco, Fabbri, Saverio, Algeri, Michela, Merlini, Piera, Giannattasio, Cristina, Morelli, Martina, Maloberti, A, Toscani, G, Busti, A, Tognola, C, Intravaia, R, De Censi, L, Galasso, M, Daus, F, Giani, V, Gualini, E, Garofani, I, Riccio, A, Biolcati, M, Fabbri, S, Algeri, M, Merlini, P, Giannattasio, C, Morelli, M, Maloberti, Alessandro, Toscani, Giorgio, Busti, Andrea, Tognola, Chiara, Intravaia, Rita Cristina Mi, De Censi, Lorenzo, Galasso, Michele, Daus, Franesca, Giani, Valentina, Gualini, Elena, Garofani, Ilaria, Riccio, Alfonso, Biolcati, Marco, Fabbri, Saverio, Algeri, Michela, Merlini, Piera, Giannattasio, Cristina, and Morelli, Martina

Published
2024

4. HYPERTRIGLYCERIDEMIA IN PATIENTS WITH ACUTE AND CHRONIC CORONARY SYNDROME: PREVALENCE AND THEIR ASSOCIATION WITH EXTREME CARDIOVASCULAR RISK AND LEFT VENTRICULAR FUNCTION

Author

Maloberti, A, Rosa, A, Toscani, G, Caccia, A, Gualini, E, Pezzoli, S, Morelli, M, Busti, A, Colombo, V, Tognola, C, Algeri, M, Intravaia, R, Pirola, R, Giannattasio, C, Garofani, I, Maloberti, Alessandro, Rosa, Antonio La, Toscani, Giorgio, Caccia, Andrea, Gualini, Elena, Pezzoli, Stefano, Morelli, Martina, Busti, Andrea, Colombo, Valentina, Tognola, Chiara, Algeri, Michela, Intravaia, Rita Cristina My, Pirola, Roberto, Giannattasio, Cristina, Garofani, Ilaria, Maloberti, A, Rosa, A, Toscani, G, Caccia, A, Gualini, E, Pezzoli, S, Morelli, M, Busti, A, Colombo, V, Tognola, C, Algeri, M, Intravaia, R, Pirola, R, Giannattasio, C, Garofani, I, Maloberti, Alessandro, Rosa, Antonio La, Toscani, Giorgio, Caccia, Andrea, Gualini, Elena, Pezzoli, Stefano, Morelli, Martina, Busti, Andrea, Colombo, Valentina, Tognola, Chiara, Algeri, Michela, Intravaia, Rita Cristina My, Pirola, Roberto, Giannattasio, Cristina, and Garofani, Ilaria

Published
2024

5. HYPERTENSIVE EMERGENCIES AND URGENCIES: ADHERENCE TO GUIDELIENS AND RELATIONSHIP BETWEEN BLOOD PRESSURE MANAGEMENT AND IN-HOSPITAL MORTALITY

Author

Maloberti, A, Valobra, T, Giani, V, Garofani, I, De Censi, L, Galasso, M, Colombo, V, Menna, A, Giacalone, A, Ferretti, C, Sultana, A, Gheda, S, Capsoni, N, Galbiati, F, Bombelli, M, Giannattasio, C, Maloberti, Alessandro, Valobra, Tommaso, Giani, Valentina, Garofani, Ilaria, De Censi, Lorenzo, Galasso, Michele, Colombo, Valentina, Menna, Alessandro, Annalisa, Giacalone, Ferretti, Cecilia, Sultana, Andrea, Gheda, Silvia, Capsoni, Nicolò, Galbiati, Filippo, Bombelli, Michele, Giannattasio, Cristina, Maloberti, A, Valobra, T, Giani, V, Garofani, I, De Censi, L, Galasso, M, Colombo, V, Menna, A, Giacalone, A, Ferretti, C, Sultana, A, Gheda, S, Capsoni, N, Galbiati, F, Bombelli, M, Giannattasio, C, Maloberti, Alessandro, Valobra, Tommaso, Giani, Valentina, Garofani, Ilaria, De Censi, Lorenzo, Galasso, Michele, Colombo, Valentina, Menna, Alessandro, Annalisa, Giacalone, Ferretti, Cecilia, Sultana, Andrea, Gheda, Silvia, Capsoni, Nicolò, Galbiati, Filippo, Bombelli, Michele, and Giannattasio, Cristina

Published
2024

6. Natural history and clinical burden of moderate aortic stenosis: a systematic review and explorative meta-analysis

Author

Morelli, M, Galasso, M, Esposito, G, Soriano, F, Nava, S, Da Pozzo, C, Bossi, I, Piccaluga, E, Bruschi, G, Maloberti, A, Oliva, F, Oreglia, J, Giannattasio, C, Montalto, C, Morelli, Martina, Galasso, Michele, Esposito, Giuseppe, Soriano, Francesco Stefano, Nava, Stefano, Da Pozzo, Caterina, Bossi, Irene, Piccaluga, Emanuela, Bruschi, Giuseppe, Maloberti, Alessandro, Oliva, Fabrizio, Oreglia, Jacopo Andrea, Giannattasio, Cristina, Montalto, Claudio, Morelli, M, Galasso, M, Esposito, G, Soriano, F, Nava, S, Da Pozzo, C, Bossi, I, Piccaluga, E, Bruschi, G, Maloberti, A, Oliva, F, Oreglia, J, Giannattasio, C, Montalto, C, Morelli, Martina, Galasso, Michele, Esposito, Giuseppe, Soriano, Francesco Stefano, Nava, Stefano, Da Pozzo, Caterina, Bossi, Irene, Piccaluga, Emanuela, Bruschi, Giuseppe, Maloberti, Alessandro, Oliva, Fabrizio, Oreglia, Jacopo Andrea, Giannattasio, Cristina, and Montalto, Claudio

Abstract

Aims: The mortality risk of patients with moderate aortic stenosis is not well known, but recent studies suggested that it might negatively affect prognosis. We aimed to assess the natural history and clinical burden of moderate aortic stenosis and to investigate the interaction of patients' baseline characteristics with prognosis. Methods: Systematic research was conducted on PubMed. The inclusion criteria were inclusion of patients with moderate aortic stenosis; and report of the survival at 1-year follow-up (minimum). Incidence ratios related to all-cause mortality in patients and controls of each study were estimated and then pooled using a fixed effects model. All patients with mild aortic stenosis or without aortic stenosis were considered controls. Meta-regression analysis was performed to assess the impact of left ventricular ejection fraction and age on the prognosis of patients with moderate aortic stenosis. Results: Fifteen studies and 11 596 patients with moderate aortic stenosis were included. All-cause mortality was significantly higher among patients with moderate aortic stenosis than in controls in all timeframes analysed (all P < 0.0001). Left ventricular ejection fraction and sex did not significantly impact on the prognosis of patients with moderate aortic stenosis (P = 0.4584 and P = 0.5792), while increasing age showed a significant interaction with mortality (estimate = 0.0067; 95% confidence interval: 0.0007-0.0127; P = 0.0323). Conclusion: Moderate aortic stenosis is associated with reduced survival. Further studies are necessary to confirm the prognostic impact of this valvulopathy and the possible benefit of aortic valve replacement.

Published
2023

7. Outcome and Morphofunctional Changes on Cardiac Magnetic Resonance in Patients With Acute Myocarditis Following mRNA COVID-19 Vaccination

Author

Ammirati, E, Lupi, L, Palazzini, M, Ciabatti, M, Rossi, V, Gentile, P, Uribarri, A, Vecchio, C, Nassiacos, D, Cereda, A, Conca, C, Tumminello, G, Piriou, N, Lelarge, C, Pedrotti, P, Stucchi, M, Peretto, G, Galasso, M, Huang, F, Ianni, U, Procopio, A, Saponara, G, Cimaglia, P, Tomasoni, D, Moroni, F, Turco, A, Sala, S, Di Tano, G, Bollano, E, Moro, C, Abbate, A, Della Bona, R, Porto, I, Carugo, S, Campodonico, J, Pontone, G, Grosu, A, Bolognese, L, Salamanca, J, Diez-Villanueva, P, Ozieranski, K, Tyminska, A, Sardo Infirri, L, Bromage, D, Cannatà, A, Hong, K, Adamo, M, Quattrocchi, G, Foà, A, Potena, L, Garascia, A, Giannattasio, C, Adler, E, Sinagra, G, Ruschitzka, F, Camici, P, Metra, M, Pieroni, M, Ammirati, Enrico, Lupi, Laura, Palazzini, Matteo, Ciabatti, Michele, Rossi, Valentina A, Gentile, Piero, Uribarri, Aitor, Vecchio, Chiara R, Nassiacos, Daniele, Cereda, Alberto, Conca, Cristina, Tumminello, Gabriele, Piriou, Nicolas, Lelarge, Coline, Pedrotti, Patrizia, Stucchi, Miriam, Peretto, Giovanni, Galasso, Michele, Huang, Florent, Ianni, Umberto, Procopio, Antonio, Saponara, Gianluigi, Cimaglia, Paolo, Tomasoni, Daniela, Moroni, Francesco, Turco, Annalisa, Sala, Simone, Di Tano, Giuseppe, Bollano, Entela, Moro, Claudio, Abbate, Antonio, Della Bona, Roberta, Porto, Italo, Carugo, Stefano, Campodonico, Jeness, Pontone, Gianluca, Grosu, Aurelia, Bolognese, Leonardo, Salamanca, Jorge, Diez-Villanueva, Pablo, Ozieranski, Krzysztof, Tyminska, Agata, Sardo Infirri, Loren, Bromage, Daniel, Cannatà, Antonio, Hong, Kimberly N, Adamo, Marianna, Quattrocchi, Giuseppina, Foà, Alberto, Potena, Luciano, Garascia, Andrea, Giannattasio, Cristina, Adler, Eric D, Sinagra, Gianfranco, Ruschitzka, Frank, Camici, Paolo G, Metra, Marco, Pieroni, Maurizio, Ammirati, E, Lupi, L, Palazzini, M, Ciabatti, M, Rossi, V, Gentile, P, Uribarri, A, Vecchio, C, Nassiacos, D, Cereda, A, Conca, C, Tumminello, G, Piriou, N, Lelarge, C, Pedrotti, P, Stucchi, M, Peretto, G, Galasso, M, Huang, F, Ianni, U, Procopio, A, Saponara, G, Cimaglia, P, Tomasoni, D, Moroni, F, Turco, A, Sala, S, Di Tano, G, Bollano, E, Moro, C, Abbate, A, Della Bona, R, Porto, I, Carugo, S, Campodonico, J, Pontone, G, Grosu, A, Bolognese, L, Salamanca, J, Diez-Villanueva, P, Ozieranski, K, Tyminska, A, Sardo Infirri, L, Bromage, D, Cannatà, A, Hong, K, Adamo, M, Quattrocchi, G, Foà, A, Potena, L, Garascia, A, Giannattasio, C, Adler, E, Sinagra, G, Ruschitzka, F, Camici, P, Metra, M, Pieroni, M, Ammirati, Enrico, Lupi, Laura, Palazzini, Matteo, Ciabatti, Michele, Rossi, Valentina A, Gentile, Piero, Uribarri, Aitor, Vecchio, Chiara R, Nassiacos, Daniele, Cereda, Alberto, Conca, Cristina, Tumminello, Gabriele, Piriou, Nicolas, Lelarge, Coline, Pedrotti, Patrizia, Stucchi, Miriam, Peretto, Giovanni, Galasso, Michele, Huang, Florent, Ianni, Umberto, Procopio, Antonio, Saponara, Gianluigi, Cimaglia, Paolo, Tomasoni, Daniela, Moroni, Francesco, Turco, Annalisa, Sala, Simone, Di Tano, Giuseppe, Bollano, Entela, Moro, Claudio, Abbate, Antonio, Della Bona, Roberta, Porto, Italo, Carugo, Stefano, Campodonico, Jeness, Pontone, Gianluca, Grosu, Aurelia, Bolognese, Leonardo, Salamanca, Jorge, Diez-Villanueva, Pablo, Ozieranski, Krzysztof, Tyminska, Agata, Sardo Infirri, Loren, Bromage, Daniel, Cannatà, Antonio, Hong, Kimberly N, Adamo, Marianna, Quattrocchi, Giuseppina, Foà, Alberto, Potena, Luciano, Garascia, Andrea, Giannattasio, Cristina, Adler, Eric D, Sinagra, Gianfranco, Ruschitzka, Frank, Camici, Paolo G, Metra, Marco, and Pieroni, Maurizio

Published
2023

8. Serum uric acid / serum creatinine ratio as a predictor of cardiovascular events. Detection of prognostic cardiovascular cut-off values

Author

Casiglia, E, Tikhonoff, V, Virdis, A, Grassi, G, Angeli, F, Barbagallo, C, Bombelli, M, Cicero, A, Cirillo, M, Cirillo, P, Dell'Oro, R, D'Elia, L, Desideri, G, Ferri, C, Galletti, F, Gesualdo, L, Giannattasio, C, Iaccarino, G, Lippa, L, Mallamaci, F, Masi, S, Maloberti, A, Masulli, M, Mazza, A, Mengozzi, A, Muiesan, M, Nazzaro, P, Palatini, P, Parati, G, Pontremoli, R, Quarti-Trevano, F, Rattazzi, M, Reboldi, G, Rivasi, G, Salvetti, M, Tocci, G, Ungar, A, Verdecchia, P, Viazzi, F, Volpe, M, Borghi, C, Casiglia, Edoardo, Tikhonoff, Valérie, Virdis, Agostino, Grassi, Guido, Angeli, Fabio, Barbagallo, Carlo M, Bombelli, Michele, Cicero, Arrigo F G, Cirillo, Massimo, Cirillo, Pietro, Dell'Oro, Raffaella, D'elia, Lanfranco, Desideri, Giovambattista, Ferri, Claudio, Galletti, Ferruccio, Gesualdo, Loreto, Giannattasio, Cristina, Iaccarino, Guido, Lippa, Luciano, Mallamaci, Francesca, Masi, Stefano, Maloberti, Alessandro, Masulli, Maria, Mazza, Alberto, Mengozzi, Alessandro, Muiesan, Maria Lorenza, Nazzaro, Pietro, Palatini, Paolo, Parati, Gianfranco, Pontremoli, Roberto, Quarti-Trevano, Fosca, Rattazzi, Marcello, Reboldi, Gianpaolo, Rivasi, Giulia, Salvetti, Massimo, Tocci, Giuliano, Ungar, Andrea, Verdecchia, Paolo, Viazzi, Francesca, Volpe, Massimo, Borghi, Claudio, Casiglia, E, Tikhonoff, V, Virdis, A, Grassi, G, Angeli, F, Barbagallo, C, Bombelli, M, Cicero, A, Cirillo, M, Cirillo, P, Dell'Oro, R, D'Elia, L, Desideri, G, Ferri, C, Galletti, F, Gesualdo, L, Giannattasio, C, Iaccarino, G, Lippa, L, Mallamaci, F, Masi, S, Maloberti, A, Masulli, M, Mazza, A, Mengozzi, A, Muiesan, M, Nazzaro, P, Palatini, P, Parati, G, Pontremoli, R, Quarti-Trevano, F, Rattazzi, M, Reboldi, G, Rivasi, G, Salvetti, M, Tocci, G, Ungar, A, Verdecchia, P, Viazzi, F, Volpe, M, Borghi, C, Casiglia, Edoardo, Tikhonoff, Valérie, Virdis, Agostino, Grassi, Guido, Angeli, Fabio, Barbagallo, Carlo M, Bombelli, Michele, Cicero, Arrigo F G, Cirillo, Massimo, Cirillo, Pietro, Dell'Oro, Raffaella, D'elia, Lanfranco, Desideri, Giovambattista, Ferri, Claudio, Galletti, Ferruccio, Gesualdo, Loreto, Giannattasio, Cristina, Iaccarino, Guido, Lippa, Luciano, Mallamaci, Francesca, Masi, Stefano, Maloberti, Alessandro, Masulli, Maria, Mazza, Alberto, Mengozzi, Alessandro, Muiesan, Maria Lorenza, Nazzaro, Pietro, Palatini, Paolo, Parati, Gianfranco, Pontremoli, Roberto, Quarti-Trevano, Fosca, Rattazzi, Marcello, Reboldi, Gianpaolo, Rivasi, Giulia, Salvetti, Massimo, Tocci, Giuliano, Ungar, Andrea, Verdecchia, Paolo, Viazzi, Francesca, Volpe, Massimo, and Borghi, Claudio

Abstract

Objective:In the frame of the Uric Acid Right for Heart Health (URRAH) study, a nationwide multicenter study involving adult participants recruited on a regional community basis from all the territory of Italy under the patronage of the Working Group on Uric Acid and Cardiovascular Risk of the Italian Society of Hypertension, we searched for the cut-off values of the ratio between serum uric acid (SUA) and serum creatinine (sCr) able to predict cardiovascular (CV) events.Methods:Among 20 724 participants followed-up for 126 ± 64 months, after detecting cut-off by the receiver operating characteristic curves, we calculated by Cox models adjusted for confounders having CV events as dependent variable the hazard ratio (HR) of SUA/sCr > cut-off. We also verified if the role of cut-off varied with increasing SUA/sCr.Results:A plausible prognostic cut-off of SUA/sCr was found and was the same in the whole database, in men and in women (>5.35). The HR of SUA/sCr > cut-off was 1.159 (95% confidence interval [CI] 1.092-1.131, P < 0.03) in all, 1.161 (95% CI 1.021-1.335, P < 0.02) in men, and 1.444 (95% CI 1.012-1.113, P < 0.03) in women. In increasing quintiles of SUA/sCr the cut-offs were >3.08, >4.87, >5.35, >6.22 and >7.58, respectively. The HRs significantly increased from the 3rd to the 5th quintile (1.21, 95% CI 1.032-1.467, P = 0.018; 1.294, 95% CI 1.101-1.521, P = 0.002; and 1.642, 95% CI 1.405-1.919, P < 0.0001; respectively), that is, over 5.35, whereas the 2nd quintile was not significantly different from the 1st (reference).Conclusion:Having SUA/sCr >5.35 is an independent CV risk indicator both in men and women. The cut-off is dynamic and significantly increases with increasing SUA/sCr.

Published
2023

9. Outcome and Morphofunctional Changes on Cardiac Magnetic Resonance in Patients With Acute Myocarditis Following mRNA COVID-19 Vaccination

Author

Enrico Ammirati, Laura Lupi, Matteo Palazzini, Michele Ciabatti, Valentina A. Rossi, Piero Gentile, Aitor Uribarri, Chiara R. Vecchio, Daniele Nassiacos, Alberto Cereda, Cristina Conca, Gabriele Tumminello, Nicolas Piriou, Coline Lelarge, Patrizia Pedrotti, Miriam Stucchi, Giovanni Peretto, Michele Galasso, Florent Huang, Umberto Ianni, Antonio Procopio, Gianluigi Saponara, Paolo Cimaglia, Daniela Tomasoni, Francesco Moroni, Annalisa Turco, Simone Sala, Giuseppe Di Tano, Entela Bollano, Claudio Moro, Antonio Abbate, Roberta Della Bona, Italo Porto, Stefano Carugo, Jeness Campodonico, Gianluca Pontone, Aurelia Grosu, Leonardo Bolognese, Jorge Salamanca, Pablo Diez-Villanueva, Krzysztof Ozieranski, Agata Tyminska, Loren Sardo Infirri, Daniel Bromage, Antonio Cannatà, Kimberly N. Hong, Marianna Adamo, Giuseppina Quattrocchi, Alberto Foà, Luciano Potena, Andrea Garascia, Cristina Giannattasio, Eric D. Adler, Gianfranco Sinagra, Frank Ruschitzka, Paolo G. Camici, Marco Metra, Maurizio Pieroni, Ammirati, E, Lupi, L, Palazzini, M, Ciabatti, M, Rossi, V, Gentile, P, Uribarri, A, Vecchio, C, Nassiacos, D, Cereda, A, Conca, C, Tumminello, G, Piriou, N, Lelarge, C, Pedrotti, P, Stucchi, M, Peretto, G, Galasso, M, Huang, F, Ianni, U, Procopio, A, Saponara, G, Cimaglia, P, Tomasoni, D, Moroni, F, Turco, A, Sala, S, Di Tano, G, Bollano, E, Moro, C, Abbate, A, Della Bona, R, Porto, I, Carugo, S, Campodonico, J, Pontone, G, Grosu, A, Bolognese, L, Salamanca, J, Diez-Villanueva, P, Ozieranski, K, Tyminska, A, Sardo Infirri, L, Bromage, D, Cannatà, A, Hong, K, Adamo, M, Quattrocchi, G, Foà, A, Potena, L, Garascia, A, Giannattasio, C, Adler, E, Sinagra, G, Ruschitzka, F, Camici, P, Metra, M, and Pieroni, M

Subjects
myocarditi, COVID-19, COVID-19 vaccines, magnetic resonance spectroscopy, myocarditis, vaccination, Cardiology and Cardiovascular Medicine, COVID-19 vaccine
Published
2023

10. PROGNOSTIC CUTOFF OF TRIGLYCERIDES PREDICTING CARDIOVASCULAR OUTCOME IN A LARGE REGIONAL-BASED ITALIAN DATABASE

Author

Tikhonoff, V, Casiglia, E, Virdis, A, Barbagallo, C, Cirillo, M, Desideri, G, Ferri, C, Galletti, F, Grassi, G, Giannattasio, C, Iaccarino, G, Mazza, A, Muiesan, M, Palatini, P, Parati, G, Pontremoli, R, Verdecchia, P, Volpe, M, Ungar, A, Borghi, C, Tikhonoff, Valerie, Casiglia, Edoardo, Virdis, Agostino, Barbagallo, Carlo, Cirillo, Massimo, Desideri, Giambattista, Ferri, Claudio, Galletti, Ferruccio, Grassi, Guido, Giannattasio, Cristina, Iaccarino, Guido, Mazza, Alberto, Muiesan, Maria Lorenza, Palatini, Paolo, Parati, Gianfranco, Pontremoli, Roberto, Verdecchia, Paolo, Volpe, Massimo, Ungar, Andrea, Borghi, Caludio, Tikhonoff, V, Casiglia, E, Virdis, A, Barbagallo, C, Cirillo, M, Desideri, G, Ferri, C, Galletti, F, Grassi, G, Giannattasio, C, Iaccarino, G, Mazza, A, Muiesan, M, Palatini, P, Parati, G, Pontremoli, R, Verdecchia, P, Volpe, M, Ungar, A, Borghi, C, Tikhonoff, Valerie, Casiglia, Edoardo, Virdis, Agostino, Barbagallo, Carlo, Cirillo, Massimo, Desideri, Giambattista, Ferri, Claudio, Galletti, Ferruccio, Grassi, Guido, Giannattasio, Cristina, Iaccarino, Guido, Mazza, Alberto, Muiesan, Maria Lorenza, Palatini, Paolo, Parati, Gianfranco, Pontremoli, Roberto, Verdecchia, Paolo, Volpe, Massimo, Ungar, Andrea, and Borghi, Caludio

Abstract

Objective: Searching for a prognostic cut-off value of triglycerides (TG) in predicting cardiovascular (CV) outcome in a large regional-based Italian database of men and women. Design and method: A nationwide multicentre database collects data on subjects aged 18 to 95 years recruited on a regional community basis from all the territory of Italy with at least 1 measure of TG and a mean follow-up of 110.1 ± 64.3 months. A total of 18,784 subjects were included in the analysis. CV outcome was defined on the basis of ICD10 codes and double-checked with general practitioners and hospital files. Multivariate dichotomic Cox regression models having CV outcome as dependent variable, adjusted for age, sex, serum uric acid, body mass index, total and HDL-cholesterol, arterial hypertension, diabetes, chronic renal disease, smoking habit, use of antihypertensive and lipid lowering drugs were preliminarily used to search for an association between TG log-transformed as a continuous variable and CV event. The conventional cut-off value of TG (150 mg/d) and the prognostic cut-off value of TG identified by means of receiver operating characteristics (ROC) curves, both able to discriminate between subjects developing a CV event, were used as independent predictors in further multivariate Cox models adjusted for the confounders listed above. Results: During 172,329 person-years of follow-up, 1910 participants experienced CV events (11.1 per 1000 age-adjusted person-years). In Cox analysis, TG as a continuous variable was a significant predictor of CV event [odds ratio, OR, 1.189 (1.060-1.334), p = 0.003]. ROC curve showed that > 105 mg/dl (95%CI 75.8-129.3, sensitivity 61.7, specificity 48.8, p < 0.0001) was the prognostic cut-off value for CV event. The conventional cut-off (150 mg/dl) and that identified by ROC curve (105 mg/dl) were both accepted as multivariate predictors in separate Cox analyses, the hazard ratios being 1.157 (95%CI 1.037-1.290, p = 0.009) and 1.137 (95%C

Published
2022

11. SERUM URIC ACID, LEFT VENTRICULAR MASS AND CARDIOVASCULAR DEATH. THE URIC ACID RIGHT FOR HEART HEALTH (URRAH) STUDY

Author

Muiesan, M, Salvetti, M, Paini, A, Rosei, C, Virdis, A, Casiglia, E, Tikhonoff, V, Barbagallo, C, Cirillo, M, Desideri, G, Ferri, C, Galletti, F, Giannattasio, C, Iaccarino, G, Mallamaci, F, Masi, S, Mazza, A, Palatini, P, Pontremoli, R, Verdecchia, P, Volpe, M, Grassi, G, Borghi, C, Muiesan, Maria Lorenza, Salvetti, Massimo, Paini, Anna, Rosei, Claudia Agabiti, Virdis, Agostino, Casiglia, Edoardo, Tikhonoff, Valerie, Barbagallo, Carlo Maria, Desideri, Giovanbattista, Ferri, Claudio, Galletti, Ferruccio, Giannattasio, Cristina, Iaccarino, Guido, Mallamaci, Francesca, Masi, Stefano, Mazza, Alberto, Palatini, Paolo, Pontremoli, Roberto, Verdecchia, Paolo, Volpe, Massimo, Grassi, Guido, Borghi, Claudio, Muiesan, M, Salvetti, M, Paini, A, Rosei, C, Virdis, A, Casiglia, E, Tikhonoff, V, Barbagallo, C, Cirillo, M, Desideri, G, Ferri, C, Galletti, F, Giannattasio, C, Iaccarino, G, Mallamaci, F, Masi, S, Mazza, A, Palatini, P, Pontremoli, R, Verdecchia, P, Volpe, M, Grassi, G, Borghi, C, Muiesan, Maria Lorenza, Salvetti, Massimo, Paini, Anna, Rosei, Claudia Agabiti, Virdis, Agostino, Casiglia, Edoardo, Tikhonoff, Valerie, Barbagallo, Carlo Maria, Desideri, Giovanbattista, Ferri, Claudio, Galletti, Ferruccio, Giannattasio, Cristina, Iaccarino, Guido, Mallamaci, Francesca, Masi, Stefano, Mazza, Alberto, Palatini, Paolo, Pontremoli, Roberto, Verdecchia, Paolo, Volpe, Massimo, Grassi, Guido, and Borghi, Claudio

Abstract

Objective: A relationship between serum uric acid(UA)and CV events has been documented in the URRAH study.The association between UA and left ventricular mass index(LVMI)has been investigated with heterogeneous results.Aim of this study was to investigate the association between UA and LVMI and whether UA and LVMI or they combination may predict the incidence of death for CV disease(CVM)in a large Italian cohort in the frame of the Working Group on Uric Acid and Cardiovascular Risk of the Italian Society of Hypertension(SIIA). Design and method: URRAH study is a nationwide,multicentre,observational cohort study involving data on subjects aged 18to95years,recruited on a community basis from all regions of Italy under the patronage of the SIIA.CVM was defined as death due to fatal myocardial infarction,stroke,sudden cardiac death,or heart failure.Multivariate Cox regression models having CVM as dependent variables,adjusted for age,sex,BMI, SBP,glycemia,total cholesterol,triglycerides,HDL-cholesterol,smoking and estimated glomerular filtration rate(eGFR)were used to search for an association between UAandLVMI as a continuous variable and CVM.LVH was defined asLVMI> 95 g/m2 in women and 115 g/m2 in men. Results: 10733 subjects(mean age,54years;51þmale)with echocardiographic LVMI measurements were included in the analysis study.A significant association between UA and LVMI was confirmed in multiple regression analysis in both sexes(men:beta0,095,F5.47,P < 0.001;women:beta0,069,F4.36,P < 0.001).During follow-up(median 130months),319subjects died for a CVevent,including myocardial infarction, angina pectoris, congestive heart failure and cerebrovascular disease.Previously identified sex specific cut off values(5.6 mg/dl men,5.1 mg/dl women)and LVH were used to define 4 different groups(normal UA and LVMI,increased UA and no LVH,normal UA and LVH,increased UA and LVH).Kaplan-Meier curves showed a significantly poorer survival rate in the group with higher UA and LV

Published
2022

12. Acute cardiovascular syndrome in the Italian multiethnic society

Author

Sacco, A, Palazzini, M, Portoghese, A, Ruzzenenti, G, De Ponti, L, Morici, N, Brunelli, D, Giannattasio, C, Oliva, F, Sacco, Alice, Palazzini, Matteo, Portoghese, Alessandro, Ruzzenenti, Giacomo, De Ponti, Laura, Morici, Nuccia, Brunelli, Dario, Giannattasio, Cristina, Oliva, Fabrizio, Sacco, A, Palazzini, M, Portoghese, A, Ruzzenenti, G, De Ponti, L, Morici, N, Brunelli, D, Giannattasio, C, Oliva, F, Sacco, Alice, Palazzini, Matteo, Portoghese, Alessandro, Ruzzenenti, Giacomo, De Ponti, Laura, Morici, Nuccia, Brunelli, Dario, Giannattasio, Cristina, and Oliva, Fabrizio

Published
2022

15. Acute cardiovascular syndrome in the Italian multiethnic society

Author

Dario Brunelli, Alessandro Portoghese, Matteo Palazzini, Laura De Ponti, Cristina Giannattasio, Giacomo Ruzzenenti, Nuccia Morici, Alice Sacco, Fabrizio Oliva, Sacco, A, Palazzini, M, Portoghese, A, Ruzzenenti, G, De Ponti, L, Morici, N, Brunelli, D, Giannattasio, C, and Oliva, F

Subjects
Male, medicine.medical_specialty, Younger age, medicine.medical_treatment, Cardiovascular risk factors, Ethnic group, cardiovascular, etnicity, Revascularization, Cohort Studies, Coronary artery disease, Epidemiology, Diabetes Mellitus, Humans, Medicine, Acute Coronary Syndrome, Triglycerides, Aged, Retrospective Studies, business.industry, Racial Groups, Smoking, Retrospective cohort study, Cholesterol, LDL, General Medicine, Middle Aged, medicine.disease, Coronary arteries, medicine.anatomical_structure, Italy, Emergency medicine, Female, Cardiology and Cardiovascular Medicine, business
Abstract

BACKGROUND In multiethnic societies, it has frequently and repeatedly been shown that some minority groups have higher rates of traditional coronary artery disease (CAD) risk factors, different rates of treatment with revascularization procedures, and excess morbidity and mortality from CAD when compared with the white population. In the last two decades, Italy is becoming a diverse society with more than five millions of inhabitants from minority ethnic groups: for this reason, we decided to investigate whether ethnic differences in our metropolitan area are similar compared with the experience of Western countries. METHODS AND RESULTS We performed a retrospective cohort study of 1285 patients with acute coronary syndromes (ACS) hospitalized at Intensive Cardiac Care Unit (ICCU), Heart Center of ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy between 2014 and the end of 2019. Six percent of these patients were South-Asian, North-African, and South-American. Despite the younger age of nonwhite patients, their comorbid conditions and traditional cardiovascular risk factors showed peculiar differences. We did not observe any difference in terms of the number of coronary arteries involved at the enrollment, patients candidate to coronary artery bypass graft and either intra-hospital or at follow-up mortality. Nevertheless, the rate of re-infarction at follow-up was significantly higher in the nonwhite group. CONCLUSION We believe that a better knowledge and understanding of epidemiological changes in Italian society could improve our clinical practice, in particular, in order to better customize treatments and therapies.

Published
2022

16. IMPORTANCE OF URIC ACID THRESHOLD IN ITS CORRELATION WITH METABOLIC SYNDROME

Author

Alessandro Maloberti, Ilaria Garofani, Stefano Fumagalli, Claudio Mario Ciampi, Paolo Ossola, Marco Carbonaro, Massimiliano Monticelli, Giovanni Tavecchia, Michele Bombelli, Cristina Giannattasio, Maloberti, A, Garofani, I, Fumagalli, S, Ciampi, C, Ossola, P, Carbonaro, M, Monticelli, M, Tavecchia, G, Bombelli, M, and Giannattasio, C

Subjects
Physiology, URIC ACID, Internal Medicine, Cardiology and Cardiovascular Medicine, METABOLIC SYNDROME
Abstract

Objective: The relationship between Hyperuricemia and Cardiovascular risk has been established but whether or not a correlation between Serum Uric Acid (SUA) and Metabolic Syndrome (MS) exists is still a matter of debate. Indeed whether SUA level is part of MS diagnosis or just a pure marker of an unfavourable metabolic profile has not been demonstrated. Besides it's unknown whether SUA's addition to MS definition makes a difference in terms of prognosis. In our study we focused on evaluating in a group of hypertensive patients, the correlation between MS diagnosis and SUA defined with two different cut-off: 1) > 6 mg/dL for women and > 7 for men (classic cut-off); 2) > 5.6 mg/dL for both sexes (recently proposed by the URRAH Project). Design and method: We enrolled 473 Hypertensive patients followed by the Hypertension Unit of San Gerardo Hospital (Monza, Italy), in which SUA was measured. Patients with Hyperuricemia were identified according to the two different thresholds. NCEP-ATP-III criteria were used for diagnosis of MS. Results: MS was diagnosed in 33.6% while Hyperuricemia was found in 14.8% of subjects according to the traditional cut-off and 35.9% according to URRAH study's cut-off. Hyperuricemia and MS coexist in 9.7% (traditional cut-off) and 17.3% (URRAH's threshold) of the population. Hyperuricemia was more frequent in MS than in non-MS subjects (29 vs 7.6%, p-value < 0.0001 for cut-off 6/7 mg/dL and 51.6 vs 28.0%, p-value < 0.0001 for cut-off 5.6 mg/dL). Linear regression models showed that SUA is related to MS diagnosis (β = 1.597, p-value < 0.0001). At logistic analysis Hyperuricemia was strongly related to MS when defined by the HURRAH's cut-off (OR = 0.303, p-value < 0.0001). The same relation is weak, although significan, when Hyperuricemia was defined by the classic cut-off (OR = 0.182, p-value < 0.0001). Conclusions: Hyperuricemia is related with MS diagnosis especially when defined by the recently defined cut-off of 5.6 mg/dL.

Published
2022

17. PROGNOSTIC CUTOFF OF TRIGLYCERIDES PREDICTING CARDIOVASCULAR OUTCOME IN A LARGE REGIONAL-BASED ITALIAN DATABASE

Author

Valerie Tikhonoff, Edoardo Casiglia, Agostino Virdis, Carlo Barbagallo, Massimo Cirillo, Giambattista Desideri, Claudio Ferri, Ferruccio Galletti, Guido Grassi, Cristina Giannattasio, Guido Iaccarino, Alberto Mazza, Maria Lorenza Muiesan, Paolo Palatini, Gianfranco Parati, Roberto Pontremoli, Paolo Verdecchia, Massimo Volpe, Andrea Ungar, Caludio Borghi, Tikhonoff, V, Casiglia, E, Virdis, A, Barbagallo, C, Cirillo, M, Desideri, G, Ferri, C, Galletti, F, Grassi, G, Giannattasio, C, Iaccarino, G, Mazza, A, Muiesan, M, Palatini, P, Parati, G, Pontremoli, R, Verdecchia, P, Volpe, M, Ungar, A, and Borghi, C

Subjects
triglycerides, cardiovascular risk, prognostic value, Physiology, Internal Medicine, Cardiology and Cardiovascular Medicine
Abstract

Objective: Searching for a prognostic cut-off value of triglycerides (TG) in predicting cardiovascular (CV) outcome in a large regional-based Italian database of men and women. Design and method: A nationwide multicentre database collects data on subjects aged 18 to 95 years recruited on a regional community basis from all the territory of Italy with at least 1 measure of TG and a mean follow-up of 110.1 ± 64.3 months. A total of 18,784 subjects were included in the analysis. CV outcome was defined on the basis of ICD10 codes and double-checked with general practitioners and hospital files. Multivariate dichotomic Cox regression models having CV outcome as dependent variable, adjusted for age, sex, serum uric acid, body mass index, total and HDL-cholesterol, arterial hypertension, diabetes, chronic renal disease, smoking habit, use of antihypertensive and lipid lowering drugs were preliminarily used to search for an association between TG log-transformed as a continuous variable and CV event. The conventional cut-off value of TG (150 mg/d) and the prognostic cut-off value of TG identified by means of receiver operating characteristics (ROC) curves, both able to discriminate between subjects developing a CV event, were used as independent predictors in further multivariate Cox models adjusted for the confounders listed above. Results: During 172,329 person-years of follow-up, 1910 participants experienced CV events (11.1 per 1000 age-adjusted person-years). In Cox analysis, TG as a continuous variable was a significant predictor of CV event [odds ratio, OR, 1.189 (1.060-1.334), p = 0.003]. ROC curve showed that > 105 mg/dl (95%CI 75.8-129.3, sensitivity 61.7, specificity 48.8, p < 0.0001) was the prognostic cut-off value for CV event. The conventional cut-off (150 mg/dl) and that identified by ROC curve (105 mg/dl) were both accepted as multivariate predictors in separate Cox analyses, the hazard ratios being 1.157 (95%CI 1.037-1.290, p = 0.009) and 1.137 (95%CI 1.023-1.263, p = 0.016), respectively. Nevertheless, we observed that cut-offs of TG between 89 and 105 mg/dl, when played in the multivariate Cox analyses, seems to be protective as well. Conclusions: In conclusion, lower than expected prognostic cut-off value of TG for CV event do exist.

Published
2022

18. SERUM URIC ACID, LEFT VENTRICULAR MASS AND CARDIOVASCULAR DEATH. THE URIC ACID RIGHT FOR HEART HEALTH (URRAH) STUDY

Author

Maria Lorenza Muiesan, Massimo Salvetti, Anna Paini, Claudia Agabiti Rosei, Agostino Virdis, Edoardo Casiglia, Valerie Tikhonoff, Carlo Maria Barbagallo, M Cirillo, Giovanbattista Desideri, Claudio Ferri, Ferruccio Galletti, Cristina Giannattasio, Guido Iaccarino, Francesca Mallamaci, Stefano Masi, Alberto Mazza, Paolo Palatini, Roberto Pontremoli, Paolo Verdecchia, Massimo Volpe, Guido Grassi, Claudio Borghi, Muiesan, M, Salvetti, M, Paini, A, Rosei, C, Virdis, A, Casiglia, E, Tikhonoff, V, Barbagallo, C, Cirillo, M, Desideri, G, Ferri, C, Galletti, F, Giannattasio, C, Iaccarino, G, Mallamaci, F, Masi, S, Mazza, A, Palatini, P, Pontremoli, R, Verdecchia, P, Volpe, M, Grassi, G, and Borghi, C

Subjects
Physiology, Internal Medicine, SERUM URIC ACID, LEFT VENTRICULAR MASS, CARDIOVASCULAR DEATH, Cardiology and Cardiovascular Medicine
Abstract

Objective: A relationship between serum uric acid(UA)and CV events has been documented in the URRAH study.The association between UA and left ventricular mass index(LVMI)has been investigated with heterogeneous results.Aim of this study was to investigate the association between UA and LVMI and whether UA and LVMI or they combination may predict the incidence of death for CV disease(CVM)in a large Italian cohort in the frame of the Working Group on Uric Acid and Cardiovascular Risk of the Italian Society of Hypertension(SIIA). Design and method: URRAH study is a nationwide,multicentre,observational cohort study involving data on subjects aged 18to95years,recruited on a community basis from all regions of Italy under the patronage of the SIIA.CVM was defined as death due to fatal myocardial infarction,stroke,sudden cardiac death,or heart failure.Multivariate Cox regression models having CVM as dependent variables,adjusted for age,sex,BMI, SBP,glycemia,total cholesterol,triglycerides,HDL-cholesterol,smoking and estimated glomerular filtration rate(eGFR)were used to search for an association between UAandLVMI as a continuous variable and CVM.LVH was defined asLVMI> 95 g/m2 in women and 115 g/m2 in men. Results: 10733 subjects(mean age,54years;51þmale)with echocardiographic LVMI measurements were included in the analysis study.A significant association between UA and LVMI was confirmed in multiple regression analysis in both sexes(men:beta0,095,F5.47,P < 0.001;women:beta0,069,F4.36,P < 0.001).During follow-up(median 130months),319subjects died for a CVevent,including myocardial infarction, angina pectoris, congestive heart failure and cerebrovascular disease.Previously identified sex specific cut off values(5.6 mg/dl men,5.1 mg/dl women)and LVH were used to define 4 different groups(normal UA and LVMI,increased UA and no LVH,normal UA and LVH,increased UA and LVH).Kaplan-Meier curves showed a significantly poorer survival rate in the group with higher UA and LVMI(log-rank chi-square298.105;P < 0.0001).Multivariate Cox regression analysis showed that in women LVH alone[HR2,25(1.076to4,721);P = 0.03]and the combination of higher UA and LVH[HR3,785(1.789to8.008);P = 0.001],but not hyperuricemia alone,were associated with a higher risk of CVD,while in men hyperuricemia without LVH[HR2.338(1.292to4.232);P = 0.005],LVH without hyperuricemia[HR3.008(1.750to5.449);P = 0.001]and their combination[HR5.273(3.044to9.135);P = 0.001]were all associated with a higher incidence of CVM. Conclusions: Our findings demonstrate that UAis independently associated with LVMI and suggest that combination of hyperuricemia with LVH is an independent and powerful predictor for CVM both in men and women.The association between UAandCVD events may be explained in part because of a direct association of UAwithLVMI.

Published
2022

19. Serum uric acid, predicts heart failure in a large Italian cohort: search for a cut-off value the URic acid Right for heArt Health study

Author

Muiesan, M, Salvetti, M, Virdis, A, Masi, S, Casiglia, E, Tikhonoff, V, Barbagallo, C, Bombelli, M, Cicero, A, Cirillo, M, Cirillo, P, Desideri, G, D’Eliak, L, Ferri, C, Galletti, F, Gesualdo, L, Giannattasio, C, Iaccarino, G, Mallamaci, F, Maloberti, A, Mazza, A, Nazzaro, P, Palatini, P, Parati, G, Pontremoli, R, Rattazzi, M, Rivasi, G, Tocci, G, Ungar, A, Verdecchia, P, Viazzi, F, Volpe, M, Grassi, G, Borghi, C, Muiesan, Maria L., Salvetti, Massimo, Virdis, Agostino, Masi, Stefano, Casiglia, Edoardo, Tikhonoff, Valérie, Barbagallo, Carlo M., Bombelli, Michele, Cicero, Arrigo F. G., Cirillo, Massimo, Cirillo, Pietro, Desideri, Giovambattista, D’Eliak, Lanfranco, Ferri, Claudio, Galletti, Ferruccio, Gesualdo, Loreto, Giannattasio, Cristina, Iaccarino, Guido, Mallamaci, Francesca, Maloberti, Alessandro, Mazza, Alberto, Nazzaro, Pietro, Palatini, Paolo, Parati, Gianfranco, Pontremoli, Roberto, Rattazzi, Marcello, Rivasi, Giulia, Tocci, Giuliano, Ungar, Andrea, Verdecchia, Paolo, Viazzi, Francesca, Volpe, Massimo, Grassi, Guido, Borghi, Claudio, Muiesan, M, Salvetti, M, Virdis, A, Masi, S, Casiglia, E, Tikhonoff, V, Barbagallo, C, Bombelli, M, Cicero, A, Cirillo, M, Cirillo, P, Desideri, G, D’Eliak, L, Ferri, C, Galletti, F, Gesualdo, L, Giannattasio, C, Iaccarino, G, Mallamaci, F, Maloberti, A, Mazza, A, Nazzaro, P, Palatini, P, Parati, G, Pontremoli, R, Rattazzi, M, Rivasi, G, Tocci, G, Ungar, A, Verdecchia, P, Viazzi, F, Volpe, M, Grassi, G, Borghi, C, Muiesan, Maria L., Salvetti, Massimo, Virdis, Agostino, Masi, Stefano, Casiglia, Edoardo, Tikhonoff, Valérie, Barbagallo, Carlo M., Bombelli, Michele, Cicero, Arrigo F. G., Cirillo, Massimo, Cirillo, Pietro, Desideri, Giovambattista, D’Eliak, Lanfranco, Ferri, Claudio, Galletti, Ferruccio, Gesualdo, Loreto, Giannattasio, Cristina, Iaccarino, Guido, Mallamaci, Francesca, Maloberti, Alessandro, Mazza, Alberto, Nazzaro, Pietro, Palatini, Paolo, Parati, Gianfranco, Pontremoli, Roberto, Rattazzi, Marcello, Rivasi, Giulia, Tocci, Giuliano, Ungar, Andrea, Verdecchia, Paolo, Viazzi, Francesca, Volpe, Massimo, Grassi, Guido, and Borghi, Claudio

Abstract

OBJECTIVE: To assess the prognostic cut-off values of serum uric acid (SUA) in predicting fatal and morbid heart failure in a large Italian cohort in the frame of the Working Group on Uric Acid and Cardiovascular Risk of the Italian Society of Hypertension. METHODS: The URic acid Right for heArt Health (URRAH) study is a nationwide, multicentre, cohort study involving data on individuals aged 18-95 years, recruited on a community basis from all regions of Italy under the patronage of the Italian Society of Hypertension with a mean follow-up period of 128 ± 65 months. Incident heart failure was defined on the basis of International Classification of Diseases Tenth Revision codes and double-checked with general practitioners and hospital files. Multivariate Cox regression models having fatal and morbid heart failure as dependent variables, adjusted for sex, age, SBP, diabetes, estimated glomerular filtration rate, smoking habit, ethanol intake, BMI, haematocrit, LDL cholesterol, previous diagnosis of heart failure and use of diuretics as possible confounders, were used to search for an association between SUA as a continuous variable and heart failure. By means of receiver operating characteristic curves, two prognostic cut-off values (one for all heart failure and one for fatal heart failure) were identified as able to discriminate between individuals doomed to develop the event. These cut-off values were used as independent predictors to divide individuals according to prognostic cut-off values in a multivariate Cox models, adjusted for confounders. RESULTS: A total of 21 386 individuals were included in the analysis. In Cox analyses, SUA as a continuous variable was a significant predictor of all [hazard ratio 1.29 (1.23-1.359), P < 0.0001] and fatal [hazard ratio 1.268 (1.121-1.35), P < 0.0001] incident heart failure. Cut-off values of SUA able to discriminate all and fatal heart failure status were identified by mean of receiver operating characteristic cur

Published
2021

20. Home blood pressure monitoring: methodology, clinical relevance and practical application: a 2021 position paper by the Working Group on Blood Pressure Monitoring and Cardiovascular Variability of the European Society of Hypertension

Author

Parati, G, Stergiou, G, Bilo, G, Kollias, A, Pengo, M, Ochoa, J, Agarwal, R, Asayama, K, Asmar, R, Burnier, M, De La Sierra, A, Giannattasio, C, Gosse, P, Head, G, Hoshide, S, Imai, Y, Kario, K, Li, Y, Manios, E, Mant, J, Mcmanus, R, Mengden, T, Mihailidou, A, Muntner, P, Myers, M, Niiranen, T, Ntineri, A, O'Brien, E, Octavio, J, Ohkubo, T, Omboni, S, Padfield, P, Palatini, P, Pellegrini, D, Postel-Vinay, N, Ramirez, A, Sharman, J, Shennan, A, Silva, E, Topouchian, J, Torlasco, C, Wang, J, Weber, M, Whelton, P, White, W, Mancia, G, Parati, Gianfranco, Stergiou, George S, Bilo, Grzegorz, Kollias, Anastasios, Pengo, Martino, Ochoa, Juan Eugenio, Agarwal, Rajiv, Asayama, Kei, Asmar, Roland, Burnier, Michel, De La Sierra, Alejandro, Giannattasio, Cristina, Gosse, Philippe, Head, Geoffrey, Hoshide, Satoshi, Imai, Yutaka, Kario, Kazuomi, Li, Yan, Manios, Efstathios, Mant, Jonathan, McManus, Richard J, Mengden, Thomas, Mihailidou, Anastasia S, Muntner, Paul, Myers, Martin, Niiranen, Teemu, Ntineri, Angeliki, O'Brien, Eoin, Octavio, José Andres, Ohkubo, Takayoshi, Omboni, Stefano, Padfield, Paul, Palatini, Paolo, Pellegrini, Dario, Postel-Vinay, Nicolas, Ramirez, Agustin J, Sharman, James E, Shennan, Andrew, Silva, Egle, Topouchian, Jirar, Torlasco, Camilla, Wang, Ji Guang, Weber, Michael A, Whelton, Paul K, White, William B, Mancia, Giuseppe, Parati, G, Stergiou, G, Bilo, G, Kollias, A, Pengo, M, Ochoa, J, Agarwal, R, Asayama, K, Asmar, R, Burnier, M, De La Sierra, A, Giannattasio, C, Gosse, P, Head, G, Hoshide, S, Imai, Y, Kario, K, Li, Y, Manios, E, Mant, J, Mcmanus, R, Mengden, T, Mihailidou, A, Muntner, P, Myers, M, Niiranen, T, Ntineri, A, O'Brien, E, Octavio, J, Ohkubo, T, Omboni, S, Padfield, P, Palatini, P, Pellegrini, D, Postel-Vinay, N, Ramirez, A, Sharman, J, Shennan, A, Silva, E, Topouchian, J, Torlasco, C, Wang, J, Weber, M, Whelton, P, White, W, Mancia, G, Parati, Gianfranco, Stergiou, George S, Bilo, Grzegorz, Kollias, Anastasios, Pengo, Martino, Ochoa, Juan Eugenio, Agarwal, Rajiv, Asayama, Kei, Asmar, Roland, Burnier, Michel, De La Sierra, Alejandro, Giannattasio, Cristina, Gosse, Philippe, Head, Geoffrey, Hoshide, Satoshi, Imai, Yutaka, Kario, Kazuomi, Li, Yan, Manios, Efstathios, Mant, Jonathan, McManus, Richard J, Mengden, Thomas, Mihailidou, Anastasia S, Muntner, Paul, Myers, Martin, Niiranen, Teemu, Ntineri, Angeliki, O'Brien, Eoin, Octavio, José Andres, Ohkubo, Takayoshi, Omboni, Stefano, Padfield, Paul, Palatini, Paolo, Pellegrini, Dario, Postel-Vinay, Nicolas, Ramirez, Agustin J, Sharman, James E, Shennan, Andrew, Silva, Egle, Topouchian, Jirar, Torlasco, Camilla, Wang, Ji Guang, Weber, Michael A, Whelton, Paul K, White, William B, and Mancia, Giuseppe

Abstract

The present paper provides an update of previous recommendations on Home Blood Pressure Monitoring from the European Society of Hypertension (ESH) Working Group on Blood Pressure Monitoring and Cardiovascular Variability sequentially published in years 2000, 2008 and 2010. This update has taken into account new evidence in this field, including a recent statement by the American Heart association, as well as technological developments, which have occurred over the past 20 years. The present document has been developed by the same ESH Working Group with inputs from an international team of experts, and has been endorsed by the ESH.

Published
2021

21. Determinants of healing among patients with coronavirus disease 2019: the results of the SARS-RAS study of the Italian Society of Hypertension

Author

Mancusi, C, Grassi, G, Borghi, C, Carugo, S, Fallo, F, Ferri, C, Giannattasio, C, Grassi, D, Letizia, C, Minuz, P, Muiesan, M, Perlini, S, Pucci, G, Rizzoni, D, Salvetti, M, Sarzani, R, Sechi, L, Veglio, F, Volpe, M, Iaccarino, G, Mancusi, Costantino, Grassi, Guido, Borghi, Claudio, Carugo, Stefano, Fallo, Francesco, Ferri, Claudio, Giannattasio, Cristina, Grassi, Davide, Letizia, Claudio, Minuz, Pietro, Muiesan, Maria Lorenza, Perlini, Stefano, Pucci, Giacomo, Rizzoni, Damiano, Salvetti, Massimo, Sarzani, Riccardo, Sechi, Leonardo, Veglio, Franco, Volpe, Massimo, Iaccarino, Guido, Mancusi, C, Grassi, G, Borghi, C, Carugo, S, Fallo, F, Ferri, C, Giannattasio, C, Grassi, D, Letizia, C, Minuz, P, Muiesan, M, Perlini, S, Pucci, G, Rizzoni, D, Salvetti, M, Sarzani, R, Sechi, L, Veglio, F, Volpe, M, Iaccarino, G, Mancusi, Costantino, Grassi, Guido, Borghi, Claudio, Carugo, Stefano, Fallo, Francesco, Ferri, Claudio, Giannattasio, Cristina, Grassi, Davide, Letizia, Claudio, Minuz, Pietro, Muiesan, Maria Lorenza, Perlini, Stefano, Pucci, Giacomo, Rizzoni, Damiano, Salvetti, Massimo, Sarzani, Riccardo, Sechi, Leonardo, Veglio, Franco, Volpe, Massimo, and Iaccarino, Guido

Abstract

OBJECTIVE: The burst of COVID-19 epidemics in Italy prompted the Italian Society of Hypertension to start an observational study to explore the characteristics of the hospitalized victims of the disease. The current analysis aimed to investigate the predictors of healing among Italian COVID-19 patients. We also assessed the effect of angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers on the outcome. METHODS: We designed a cross-sectional, observational, multicenter, nationwide survey in Italy to explore the demographic and clinical characteristics of patients with confirmed COVID-19 infection. We analyzed information from 2446 charts of Italian patients admitted for certified COVID-19 in 27 hospitals. Healing from COVID-19 infection, defined as two consecutive negative swabs, was reported in 544 patients (22.2%), 95% of them were hospitalized. RESULTS: Age and Charlson Comorbidity Index were significantly lower in healing compared with nonhealing patients (63 ± 15 vs. 69 ± 15 and 2 ± 2 vs. 3 ± 2, both P < 0.05). In multivariable regression model, predictors of healing were younger age (OR: 0.99; 95% CI 0.98-0.99, P = 0.0001), absence of chronic kidney disease (OR: 0.35; 95% CI 0.17-0.70, P = 0.003) or heart failure (OR: 0.44; 95% CI, 0.28-0.70, P = 0.001). In the subgroup of patients suffering from hypertension and/or heart failure (n = 1498), no differences were observed in the use of ACE inhibitors and angiotensin receptor blockers. CONCLUSION: Our study demonstrated that younger age and absence of comorbidities play a major role in determining healing in patients with COVID-19. No effects of ACE inhibitors and angiotensin receptor blockers on the outcome was reported.

Published
2021

22. Serum uric acid / serum creatinine ratio as a predictor of cardiovascular events. Detection of prognostic cardiovascular cut-off values.

Author

Casiglia, Edoardo, Tikhonoff, Valérie, Virdis, Agostino, Grassi, Guido, Angeli, Fabio, Barbagallo, Carlo M., Bombelli, Michele, Cicero, Arrigo F.G., Cirillo, Massimo, Cirillo, Pietro, Dell'Oro, Raffaella, D'elia, Lanfranco, Desideri, Giovambattista, Ferri, Claudio, Galletti, Ferruccio, Gesualdo, Loreto, Giannattasio, Cristina, Iaccarino, Guido, Lippa, Luciano, and Mallamaci, Francesca

Published
2023
Full Text
View/download PDF

23. 24-HOUR CENTRAL BLOOD PRESSURE: REFERENCE VALUES FOR HEALTHY INDIVIDUALS. THE INTERNATIONAL 24HOUR AMBULATORY AORTIC BLOOD PRESSURE CONSORTIUM (I24ABC)

Author

Weber, T, Protogerou, A, Wassertheurer, S, Agharazii, M, Argyris, A, Bahous, S, Banegas, J, Blacher, J, Brandao, A, Cruz, J, Giannattasio, C, Jankowski, P, Li, Y, Maloberti, A, Mcdonnel, B, Mceniery, C, Mota Gomes, M, Machado Gomes, A, Graciani, A, Muiesan, M, Nemcsik, J, Rodilla, E, Schutte, A, Terentes-Printzios, D, Vallee, A, Vlachopoulos, C, Ware, L, Wilkinson, I, Zweiker, R, Sharman., J, T. Weber, A. Protogerou, S. Wassertheurer, M. Agharazii, A. Argyris, S. A. Bahous, J. R. Banegas, J. Blacher, A. A. Brandao, J. J. Cruz, C. Giannattasio, P. Jankowski, Y. Li, A. Maloberti, B. McDonnel, C. McEniery, M. A. Mota Gomes, A. Machado Gomes, A. Graciani, M. L. Muiesan, J. Nemcsik, E. Rodilla, A. Schutte, D. Terentes-Printzios, A. Vallee, C. Vlachopoulos, L. Ware, I. Wilkinson, R. Zweiker, J. Sharman., Weber, T, Protogerou, A, Wassertheurer, S, Agharazii, M, Argyris, A, Bahous, S, Banegas, J, Blacher, J, Brandao, A, Cruz, J, Giannattasio, C, Jankowski, P, Li, Y, Maloberti, A, Mcdonnel, B, Mceniery, C, Mota Gomes, M, Machado Gomes, A, Graciani, A, Muiesan, M, Nemcsik, J, Rodilla, E, Schutte, A, Terentes-Printzios, D, Vallee, A, Vlachopoulos, C, Ware, L, Wilkinson, I, Zweiker, R, Sharman., J, T. Weber, A. Protogerou, S. Wassertheurer, M. Agharazii, A. Argyris, S. A. Bahous, J. R. Banegas, J. Blacher, A. A. Brandao, J. J. Cruz, C. Giannattasio, P. Jankowski, Y. Li, A. Maloberti, B. McDonnel, C. McEniery, M. A. Mota Gomes, A. Machado Gomes, A. Graciani, M. L. Muiesan, J. Nemcsik, E. Rodilla, A. Schutte, D. Terentes-Printzios, A. Vallee, C. Vlachopoulos, L. Ware, I. Wilkinson, R. Zweiker, and J. Sharman.

Published
2019

24. STUDY OF THE EUROPEAN SOCIETY OF HYPERTENSION ON BLOOD PRESSURE CONTROL IN ESH EXCELLENCE CENTERS (BP CON ESH) - THE FIRST PRELIMINARY REPORT

Author

Jelakovic, B, Triantafyllou, A, Doumas, M, Kalaitzidis, R, Protogerou, A, Kallistratos, E, Stergiou, G, Moloberti, A, Giannattasio, C, Marketou, M, Papadakis, I, Papadopoulos, D, Pengo, M, Parati, G, Sarafidis, P, Stojanov, V, Triantafyllidi, E, Manta, E, Tsioufis, K, Agabiti-Rosei, E, Kreutz, R, Polonia, J, Januszewicz, A, Mancia, G, Jelakovic, B, Triantafyllou, A, Doumas, M, Kalaitzidis, R, Protogerou, A, Kallistratos, E, Stergiou, G, Moloberti, A, Giannattasio, C, Marketou, M, Papadakis, I, Papadopoulos, D, Pengo, M, Parati, G, Sarafidis, P, Stojanov, V, Triantafyllidi, E, Manta, E, Tsioufis, K, Agabiti-Rosei, E, Kreutz, R, Polonia, J, Januszewicz, A, and Mancia, G

Published
2021

25. The association of uric acid with mortality modifies at old age: data from the uric acid right for heart health (URRAH) study.

Author

Ungar, Andrea, Rivasi, Giulia, Di Bari, Mauro, Virdis, Agostino, Casiglia, Edoardo, Masi, Stefano, Mengozzi, Alessandro, Barbagallo, Carlo M., Bombelli, Michele, Bruno, Bernardino, Cicero, Arrigo F.G., Cirillo, Massimo, Cirillo, Pietro, Desideri, Giovambattista, D'elia, Lanfranco, Ferri, Claudio, Galletti, Ferruccio, Gesualdo, Loreto, Giannattasio, Cristina, and Iaccarino, Guido

Published
2022
Full Text
View/download PDF

26. SUBCLINICAL HYPERTENSION-MEDIATED ORGAN DAMAGE AND PROGNOSIS IN PATIENTS WITH HYPERTENSIVE EMERGENCIES AND URGENCIES: REPORT FROM THE ONGOING MULTICENTER ERIDANO STUDY.

Author

Cesareo, Marco, Vallelonga, Fabrizio, Sanapo, Martina, Leone, Dario, Lupia, Enrico, Morello, Fulvio, Totaro, Silvia, Aggiusti, Carlo, Salvetti, Massimo, Ioverno, Antonella, Maloberti, Alessandro, Fucile, Ilaria, Cipollini, Franco, Nesti, Nicola, Mancusi, Costantino, Pende, Aldo, Giannattasio, Cristina, Muiesan, Maria Lorenza, and Milan, Alberto

Published
2024
Full Text
View/download PDF

29. Relationship Between 24-Hour Ambulatory Central Systolic Blood Pressure and Left Ventricular Mass: A Prospective Multicenter Study

Author

Weber, T, Wassertheurer, S, Schmidt trucksäss, A, Rodilla, E, Ablasser, C, Jankowski, P, Lorenza Muiesan, M, Giannattasio, C, Mang, C, Wilkinson, I, Kellermair, J, Hametner, B, Pascual, J, Zweiker, R, Czarnecka, D, Paini, A, Salvetti, M, Maloberti, A, Mceniery, C, GIANNATTASIO, CRISTINA, MALOBERTI, ALESSANDRO, Mceniery, C., Weber, T, Wassertheurer, S, Schmidt trucksäss, A, Rodilla, E, Ablasser, C, Jankowski, P, Lorenza Muiesan, M, Giannattasio, C, Mang, C, Wilkinson, I, Kellermair, J, Hametner, B, Pascual, J, Zweiker, R, Czarnecka, D, Paini, A, Salvetti, M, Maloberti, A, Mceniery, C, GIANNATTASIO, CRISTINA, MALOBERTI, ALESSANDRO, and Mceniery, C.

Abstract

We investigated the relationship between left ventricular mass and brachial office as well as brachial and central ambulatory systolic blood pressure in 7 European centers. Central systolic pressure was measured with a validated oscillometric device, using a transfer function, and mean/diastolic pressure calibration. M-mode images were obtained by echocardiography, and left ventricular mass was determined by one single reader blinded to blood pressure. We studied 289 participants (137 women) free from antihypertensive drugs (mean age: 50.8 years). Mean office blood pressure was 145/88 mm Hg and mean brachial and central ambulatory systolic pressures were 127 and 128 mm Hg, respectively. Mean left ventricular mass was 93.3 kg/m(2), and 25.6% had left ventricular hypertrophy. The correlation coefficient between left ventricular mass and brachial office, brachial ambulatory, and central ambulatory systolic pressure was 0.29, 0.41, and 0.47, respectively (P=0.003 for comparison between brachial office and central ambulatory systolic pressure and 0.32 for comparison between brachial and central ambulatory systolic pressure). The results were consistent for men and women, and young and old participants. The areas under the curve for prediction of left ventricular hypertrophy were 0.618, 0.635, and 0.666 for brachial office, brachial, and central ambulatory systolic pressure, respectively (P=0.03 for comparison between brachial and central ambulatory systolic pressure). In younger participants, central ambulatory systolic pressure was superior to both other measurements. Central ambulatory systolic pressure, measured with an oscillometric cuff, shows a strong trend toward a closer association with left ventricular mass and hypertrophy than brachial office/ambulatory systolic pressure

Published
2017

30. Association between uric acid and cardiac, vascular and renal target organ damage in hypertensives subjects

Author

Maloberti, A, Varrenti, M, Triglione, N, Occhi, L, Panzeri, F, Alloni, M, Giupponi, L, Vallerio, P, Casati, M, Grassi, G, Mancia, G, Giannattasio, C, A. Maloberti, M. Varrenti, N. Triglione, L. Occhi, F. Panzeri, M. Alloni, L. Giupponi, P. Vallerio, M. Casati, G. Grassi, G. Mancia, C. Giannattasio, Maloberti, A, Varrenti, M, Triglione, N, Occhi, L, Panzeri, F, Alloni, M, Giupponi, L, Vallerio, P, Casati, M, Grassi, G, Mancia, G, Giannattasio, C, A. Maloberti, M. Varrenti, N. Triglione, L. Occhi, F. Panzeri, M. Alloni, L. Giupponi, P. Vallerio, M. Casati, G. Grassi, G. Mancia, and C. Giannattasio

Published
2017

31. Home blood pressure monitoring: methodology, clinical relevance and practical application: a 2021 position paper by the Working Group on Blood Pressure Monitoring and Cardiovascular Variability of the European Society of Hypertension.

Author

Parati, Gianfranco, Stergiou, George S., Bilo, Grzegorz, Kollias, Anastasios, Pengo, Martino, Ochoa, Juan Eugenio, Agarwal, Rajiv, Kei Asayama, Asmar, Roland, Burnier, Michel, De La Sierra, Alejandro, Giannattasio, Cristina, Gosse, Philippe, Head, Geoffrey, Satoshi Hoshide, Yutaka Imai, Kazuomi Kario, Yan Li, Manios, Efstathios, and Mant, Jonathan

Published
2021
Full Text
View/download PDF

32. 24 HOUR ARTERIAL DISTENSIBILITY IS RELATED WITH ABPM NON-DIPPING PATTERN IN HIVPOSITIVE PATIENTS

Author

Varrenti, M, Maloberti, A, Vallerio, P, Panzeri, F, Pessina, L, Casadei, F, Lucente, D, D’Alessio, I, Mondellini, G, Motta, D, Moioli, C, Parati, G, Puoti, M, Giannattasio, C, PARATI, GIANFRANCO, GIANNATTASIO, CRISTINA, Varrenti, M, Maloberti, A, Vallerio, P, Panzeri, F, Pessina, L, Casadei, F, Lucente, D, D’Alessio, I, Mondellini, G, Motta, D, Moioli, C, Parati, G, Puoti, M, Giannattasio, C, PARATI, GIANFRANCO, and GIANNATTASIO, CRISTINA

Published
2016

33. Determinants of healing among patients with coronavirus disease 2019: the results of the SARS-RAS study of the Italian Society of Hypertension.

Author

Mancusi, Costantino, Grassi, Guido, Borghi, Claudio, Carugo, Stefano, Fallo, Francesco, Ferri, Claudio, Giannattasio, Cristina, Grassi, Davide, Letizia, Claudio, Minuz, Pietro, Muiesan, Maria Lorenza, Perlini, Stefano, Pucci, Giacomo, Rizzoni, Damiano, Salvetti, Massimo, Sarzani, Riccardo, Sechi, Leonardo, Veglio, Franco, Volpe, Massimo, and Iaccarino, Guido

Published
2021
Full Text
View/download PDF

34. Relationships between diuretic-related hyperuricemia and cardiovascular events: data from the URic acid Right for heArt Health study.

Author

Maloberti, Alessandro, Bombelli, Michele, Facchetti, Rita, Barbagallo, Carlo Maria, Bernardino, Bruno, Rosei, Enrico Agabiti, Casiglia, Edoardo, Cicero, Arrigo Francesco Giuseppe, Cirillo, Massimo, Cirillo, Pietro, Desideri, Giovambattista, D'elia, Lanfranco, Dell'Oro, Raffaella, Ferri, Claudio, Galletti, Ferruccio, Giannattasio, Cristina, Loreto, Gesualdo, Iaccarino, Guido, Lippa, Luciano, and Mallamaci, Francesca

Published
2021
Full Text
View/download PDF

35. Serum uric acid, predicts heart failure in a large Italian cohort: search for a cut-off value the URic acid Right for heArt Health study.

Author

Muiesan, Maria L., Salvetti, Massimo, Virdis, Agostino, Masi, Stefano, Casiglia, Edoardo, Tikhonoff, Valérie, Barbagallo, Carlo M., Bombelli, Michele, Cicero, Arrigo F. G., Cirillo, Massimo, Cirillo, Pietro, Desideri, Giovambattista, D’Eliak, Lanfranco, Ferri, Claudio, Galletti, Ferruccio, Gesualdo, Loreto, Giannattasio, Cristina, Iaccarino, Guido, Mallamaci, Francesca, and Maloberti, Alessandro

Published
2021
Full Text
View/download PDF

36. Characteristics and hospital course of patients admitted for acute cardiovascular diseases during the coronavirus disease-19 outbreak.

Author

Zorzi, Alessandro, Vio, Riccardo, Rivezzi, Francesco, Falzone, Pasquale V., Giordani, Andrea S., Condello, Chiara, Dellino, Carlo M., Deola, Petra, Gallucci, Marco, Giannattasio, Alessia, Licchelli, Luca, Lupasco, Diana, Montonati, Carolina, Ravagnin, Alberto, Sinigiani, Giulio, Torreggiani, Gianpaolo, Vianello, Riccardo, Migliore, Federico, Famoso, Giulia, and Babuin, Luciano

Published
2021
Full Text
View/download PDF

37. Serum uric acid and fatal myocardial infarction: detection of prognostic cut-off values: The URRAH (Uric Acid Right for Heart Health) study.

Author

Casiglia, Edoardo, Tikhonoff, Valérie, Virdis, Agostino, Masi, Stefano, Barbagallo, Carlo M, Bombelli, Michele, Bruno, Bernardino, Cicero, Arrigo F G, Cirillo, Massimo, Cirillo, Pietro, Desideri, Giovambattista, D'Elia, Lanfranco, Ferri, Claudio, Galletti, Ferruccio, Gesualdo, Loreto, Giannattasio, Cristina, Iaccarino, Guido, Lippa, Luciano, Mallamaci, Francesca, and Maloberti, Alessandro

Published
2020
Full Text
View/download PDF

39. MULTIDRUG RESISTANT DYSLIPIDEMIA: A CASE REPORT.

Author

Maloberti, Alessandro, Daus, Francesca, Pavanello, Chiara, Toscani, Giorgio, Riccio, Alfonso, Fabbri, Saverio, Ciampi, Claudio Mario, Caccia, Andrea, Tognola, Chiara, Algeri, Michela, Intravaia, Rita Cristina My, Merlini, Piera, Mosca, Lorena, Cavallari, Ugo, Giannattasio, Cristina, and Morelli, Marco

Published
2024
Full Text
View/download PDF

40. HYPERTENSION PHENOTYPES BASED ON BRACHIAL AND AORTIC 24HR SYSTOLIC PRESSURE AND THEIR ASSOCIATION WITH HYPERTENSION PHENOTYPES BASED ON BOTH BRACHIAL AND AORTIC 24HR SYSTOLIC PRESSURE AND THEIR ASSOCIATION WITH LEFT VENTRICULAR HYPERTROPHY: FINDINGS FROM THE I24ABC CONSORTIUM

Author

Athanasopoulou, Elpida, Weber, Thomas, Wassertheurer, Siegfried, Sharman, James E., Argyris, Antonios, Sala, Enrique Rodilla, Jankowski, Piotr, Muiesan, Maria Lorenza, Giannattasio, Cristina, Wilkinson, Ian, Hametner, Bernhard, Orter, Stefan, Mayer, Christopher, Li, Yan, Pascual, Jose Maria, Danninger, Kathrin, Karachalias, Fotis, McEniery, Carmel, Pucci, Giacomo, and Blacher, Jaques

Published
2024
Full Text
View/download PDF

41. HYPERTRIGLYCERIDEMIA IN PATIENTS WITH ACUTE AND CHRONIC CORONARY SYNDROME: PREVALENCE AND THEIR ASSOCIATION WITH EXTREME CARDIOVASCULAR RISK AND LEFT VENTRICULAR FUNCTION.

Author

Maloberti, Alessandro, Rosa, Antonio La, Toscani, Giorgio, Caccia, Andrea, Gualini, Elena, Pezzoli, Stefano, Morelli, Martina, Busti, Andrea, Colombo, Valentina, Tognola, Chiara, Algeri, Michela, Intravaia, Rita Cristina My, Pirola, Roberto, Giannattasio, Cristina, and Garofani, Ilaria

Published
2024
Full Text
View/download PDF

44. MAY MEASURE MONTH 2022 IN ITALY: RESULTS OF A NATIONWIDE SURVEY.

Author

Del Pinto, Rita, Rosei, Claudia Agabiti, Borghi, Claudio, Cottone, Santina, Fabris, Bruno, Giannattasio, Cristina, Minuz, Pietro, Mulè, Giuseppe, Nazzaro, Pietro, Parati, Gianfranco, Rattazzi, Marcello, Sarzani, Riccardo, Veglio, Franco, Vulpis, Vito, De Giorgi, Giuseppe Antonio, Di Guardo, Antonino, Dugnani, Maurizio, Saladini, Francesca, Ferri, Claudio, and Muiesan, Maria Lorenza

Published
2024
Full Text
View/download PDF

45. HYPERTENSIVE EMERGENCIES AND URGENCIES: ADHERENCE TO GUIDELIENS AND RELATIONSHIP BETWEEN BLOOD PRESSURE MANAGEMENT AND IN-HOSPITAL MORTALITY.

Author

Maloberti, Alessandro, Valobra, Tommaso, Giani, Valentina, Garofani, Ilaria, De Censi, Lorenzo, Galasso, Michele, Colombo, Valentina, Menna, Alessandro, Annalisa, Giacalone, Ferretti, Cecilia, Sultana, Andrea, Gheda, Silvia, Capsoni, Nicolò, Galbiati, Filippo, Bombelli, Michele, and Giannattasio, Cristina

Published
2024
Full Text
View/download PDF

47. Associations between psychological characteristics and total cardiovascular risk in hypertensive patients

Author

Cesana, F, Greco, A, Mascolo, M, Baroni, M, Nava, S, Alloni, M, D'Addario, M, Magrin, M, Miglioretti, M, Steca, P, Giannattasio, C, CESANA, FRANCESCA, GRECO, ANDREA, BARONI, MATTEO, NAVA, STEFANO, ALLONI, MARTA, D'ADDARIO, MARCO, MAGRIN, MARIA ELENA, MIGLIORETTI, MASSIMO, STECA, PATRIZIA, GIANNATTASIO, CRISTINA, Cesana, F, Greco, A, Mascolo, M, Baroni, M, Nava, S, Alloni, M, D'Addario, M, Magrin, M, Miglioretti, M, Steca, P, Giannattasio, C, CESANA, FRANCESCA, GRECO, ANDREA, BARONI, MATTEO, NAVA, STEFANO, ALLONI, MARTA, D'ADDARIO, MARCO, MAGRIN, MARIA ELENA, MIGLIORETTI, MASSIMO, STECA, PATRIZIA, and GIANNATTASIO, CRISTINA

Published
2014

50. Impact of body mass index and waist circumference on the long-term risk of diabetes mellitus, hypertension, and cardiac organ damage

Author

Bombelli, M, Facchetti, R, Sega, R, Carugo, S, Fodri, D, Brambilla, G, Giannattasio, C, Grassi, G, Mancia, G, BOMBELLI, MICHELE, FACCHETTI, RITA LUCIA, SEGA, ROBERTO, GIANNATTASIO, CRISTINA, GRASSI, GUIDO, MANCIA, GIUSEPPE, Bombelli, M, Facchetti, R, Sega, R, Carugo, S, Fodri, D, Brambilla, G, Giannattasio, C, Grassi, G, Mancia, G, BOMBELLI, MICHELE, FACCHETTI, RITA LUCIA, SEGA, ROBERTO, GIANNATTASIO, CRISTINA, GRASSI, GUIDO, and MANCIA, GIUSEPPE

Abstract

Obesity is associated with a higher risk of developing diabetes mellitus (DM), hypertension (HT), and left ventricular hypertrophy (LVH). The present study assessed in the general population the impact of body weight and visceral obesity on the development of alterations in glucose metabolism and cardiac structure, as well as of elevation in blood pressure. In 1412 subjects randomly selected and representative of the general population of Monza, we assessed twice (in 1990/1991 and 2000/2001) body mass index (BMI); waist circumference; office, home, and 24-hour ambulatory (24-hour) blood pressure, fasting glycemia, and left ventricular mass (echocardiography). New-onset high-risk conditions were DM; impaired fasting glucose; office, home, and 24-hour HT; and LVH. The incidence of new-onset DM; impaired fasting glucose; office, home, and 24-hour HT; and LVH increased progressively from the quintile with the lowest to the quintile with the highest BMI values. Adjusting for confounders, the risk of developing new-onset DM; impaired fasting glucose; office, home, and 24-hour HT; and LVH increased significantly for an increase of 1 kg/m 2 of BMI and 1 cm of waist circumference (respectively, 8.4% [P>0.01], 9.5% [P>0.0001], 4.2% [P>0.0001], 3.9% [P>0.001], 2.5% [P>0.05], and 5.1% [P>0.001] for BMI and 3.2% [P>0.001], 3.5% [P>0.0001], 1.8% [P>0.0001], 1.5% [P>0.0001], 1.4% [P>0.001], and 2.6% [P>0.0001]). These data provide evidence that an increase in BMI and waist circumference is associated with a linearly increased adjusted risk of developing conditions with high cardiovascular risk, such as DM, impaired fasting glucose, in-and out-of-office HT, and LVH. © 2011 American Heart Association, Inc.

Published
2011

Catalog

Books, media, physical & digital resources
See catalog results