1. The impact of ten years of infant universal Varicella vaccination in Sicily, Italy (2003-2012)
- Author
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Francesco Vitale, Giovanni Gabutti, Maria Cristina Rota, Emanuele Amodio, Fabio Tramuto, Manuela Cracchiolo, Antonella De Donno, Marcello Guido, Valentina Sciuto, Amodio, E, Tramuto, F, Cracchiolo, M, Sciuto, V, De Donno, A, Guido, M, Rota, MC, Gabutti, G, Vitale, F, Amodio, Emanuele, Tramuto, Fabio, Cracchiolo, Manuela, Sciuto, Valentina, DE DONNO, Maria Antonella, Guido, Marcello, Rota, Maria Cristina, Gabutti, Giovanni, and Vitale, Francesco
- Subjects
Adult ,Male ,Pediatrics ,medicine.medical_specialty ,Adolescent ,Immunology ,Population ,Socio-culturale ,coverage ,Varicella vaccination ,Antibodies, Viral ,Settore MED/42 - Igiene Generale E Applicata ,Chickenpox Vaccine ,Young Adult ,Chickenpox ,varicella ,Epidemiology ,Humans ,Immunology and Allergy ,Medicine ,Young adult ,Child ,education ,Disease Notification ,Sicily ,Hospitalizations ,Pharmacology ,education.field_of_study ,business.industry ,Vaccination ,Infant, Newborn ,Infant ,Notifications ,medicine.disease ,Hospitalization ,Coverage ,Universal mass vaccination ,Varicella ,Child, Preschool ,Female ,epidemiology ,notification ,business ,Birth cohort ,universal mass vaccination ,Human ,Research Paper ,hospitalization - Abstract
Introduction Universal varicella vaccination in Sicily was introduced in infant population since 2003, with a rapidly increasing coverage. Aim of the present study was to analyze changes in the epidemiology of varicella since the introduction of universal vaccination. Methods The study was performed by analyzing Sicilian administrative/clinical data on varicella case notifications and hospitalizations from 2003 to 2012 (ICD-9-CM discharge diagnosis codes 052 and 052.×). MMR+V and V coverage were also calculated for each birth cohort. Moreover, blood samples drawn in 2013/2014 from general population stratified by age were tested for varicella antibodies. Results From 2003 to 2012, 15 433 varicella cases were notified with a decreasing temporal trend (1.1/1000 population in 2003 to 0.1/1000 in 2012) (P
- Published
- 2015