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Objective To investigate the relationship between beta enolase gene two point rs121918403 (G/A), rs121918404 (G/A) polymorphism with skeletal muscle Atrophy in the patient with chronic obstructive pulmonary disease (COPD). Method Beta enolase genes were assayed by polymerase chain and one-way directed sequencing methods between 120 COPD patients and 60 age-matched controls in Kunming. Result There was no mutation in rs121918403 (G/A) and rs121918404 (G/A) of beta enolase gene in COPD patients and healthy subjects. Conclusion SNPs of two mutational sites of beta enolase are not correlated to skeletal muscle atrophy in COPD patients in Kunming. [ABSTRACT FROM AUTHOR]

Objective To investigate the effect of thoracoscopy under local anesthesia in diagnosis and treatment of tuberculous encysted pleural effusion. Method 143 patients with tuberculous encysted pleural effusion were divided into two groups according to historical comparison method: thoracoscopic group (n = 64) and control group (n =79) . The corresponding diagnosis and treatment were retrospectively analyzed, and the pathological diagnosis rate, changes in lung function, chest tightness and shortness of breath disappear, complications after treatment were compared between the two groups. Results The pathological diagnosis rate, vital capacity of lung function expected percentages ( FVC% ) and forced expiratory volume in 1 second take up of the expected (FEV1%) values in the thoracoscopic group were higher than the control group, but chest tightness, shortness of breath disappear time were lower than the control group, the differences were significant (P < 0.05) . 1 case of severe complications occurred in the thoracoscopic group. Conclusion The effect of thoracoscopy under local anesthesia is good in diagnosis and treatment of tuberculous encysted pleural effusion, it is simple and has low incidence of severe complications, so is worth clinical promotion. [ABSTRACT FROM AUTHOR]