The global spread of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has posed a threat to the public health worldwide [1]. Emerging in Wuhan, China in December 2019, this pandemic has become a major public health and economic burden on the world. SARS-CoV-2 was the seventh coronavirus identified with human infection capacity [2]. It has been stated that the spike (S) protein of 2019-nCoV had a high affinity to angiotensin-converting enzyme (ACE-2), which mediates the mechanism of the virus entrance to the target cell [3]. As the viral mutations occur during transmission, investigation of related clinical features of SARS-CoV-2 during its spread is interesting. Therefore, recording all clinical symptoms in patients with the coronavirus disease 2019 (COVID-19) is not without merit and can be a great help in timely diagnosis and treatment of the disease [4]. Children are the important part of any society. Characterizing clinical manifestations can not only contribute to the management of COVID-19 infection in children, but also provide accurate information for healthcare workers. It is well documented that children of all ages are susceptible to COVID-19, but they do not develop as much severe symptoms as adults [4]. The first pediatric case was reported on January 20, 2020, in a 10-year-old boy from Shenzhen, China and the youngest one was a 36-hour-old newborn [5,6]. The underlying cause of the lower incidence and milder symptoms of COVID-19 in children is associated with the premature ACE in children. Fever and dry cough are the most commonly reported clinical manifestations of COVID-19 among children [7]. The present study reported a 2-month-old male infant with fever and diarrhea, hospitalized in Hazrat-e Fatemeh Masoumeh Hospital, Qom city, Iran. The clinical features including symptoms, hospitalizations time, and medications were recorded and analyzed.