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Your search keyword '"Kim, Chul Hee"' showing total 9 results
Start Over Author "Kim, Chul Hee" Publisher korean association of internal medicine
9 results on '"Kim, Chul Hee"'

3. Pulmonary Diffuse Alveolar Septal Amyloidosis

Author

Kim, Chul Hee, Kim, Suhnggwon, Kwon, O Jung, Han, Sung Koo, Lee, Jung Sang, Kim, Keon Youl, Seo, Jeong Wook, and Im, Jung Gi

Subjects
Lung Diseases, Pulmonary Alveoli, Pulmonary amyloidosis, Diffuse alveolar septal, Transbronchial biopsy, Biopsy, Humans, Case Report, Female, Amyloidosis, Middle Aged
Abstract

Diffuse alveolar septal involvement is a rare form of pulmonary amyloidosis. Ante-mortem diagnosis is unusual, and most of the reported cases were diagnosed at autopsy. It has recently been reported that transbronchial lung biopsy via a flexible fiberoptic bronchoscope was a relatively safe method to confirm diffuse alveolar septal amyloidosis. We report a case of pulmonary diffuse alveolar septal amyloidosis confirmed by transbronchial lung biopsy. The patient’s chief complaints were dyspnea on exertion and epigastric pain aggravated over a one-year period, while a chest roentgenogram showed bilateral diffuse interstitial infiltration. This case also showed nephrotic syndrome, cardiac arrhythmia, congestive heart failure, a tingling sensation in both hands and multiple nodules in the gastrointestinal tracts, suggesting involvement of the kidney, heart, peripheral nerves and gastrointestinal tracts. We propose that when diffuse interstitial lung disease is present with systemic signs such as nephrotic syndrome or cardiac arrhythmia, amyloidosis should be considered as a possible diagnosis. Also, transbronchial lung biopsy may be a useful confirmative diagnostic tool.

Published
1990

6. DNA Methylation ofRUNX3in Papillary Thyroid Cancer

Author

Ko, Hee Ja, primary, Kim, Bo Yeon, additional, Jung, Chan Hee, additional, Chun, Sung Wan, additional, Mok, Ji Oh, additional, Kim, Yeo Joo, additional, Park, Hyeong Kyu, additional, Kim, Chul Hee, additional, Kim, Sang Jin, additional, Byun, Dong Won, additional, Suh, Kyo Il, additional, Yoo, Myung Hi, additional, and Kang, Sung Gu, additional

Published
2012
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8. Immunohistochemical Expression of COX-2 in Thyroid Nodules

Author

Kim, Sang Jin, primary, Lee, Jae Hak, additional, Yoon, Ji Sung, additional, Mok, Ji O, additional, Kim, Yeo Joo, additional, Park, Hyeong Kyu, additional, Kim, Chul Hee, additional, Byun, Dong Won, additional, Suh, Kyo Il, additional, and Yoo, Myung Hi, additional

Published
2003
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9. DNA methylation of RUNX3 in papillary thyroid cancer.

Author

Ko HJ, Kim BY, Jung CH, Chun SW, Mok JO, Kim YJ, Park HK, Kim CH, Kim SJ, Byun DW, Suh KI, Yoo MH, and Kang SG

Subjects
Azacitidine analogs & derivatives, Azacitidine pharmacology, Biomarkers, Tumor genetics, Carcinoma, Papillary, Cell Line, Tumor, DNA Methylation drug effects, Decitabine, Gene Expression drug effects, Humans, Thyroid Cancer, Papillary, Carcinoma genetics, Core Binding Factor Alpha 3 Subunit genetics, Thyroid Neoplasms genetics
Abstract

Background/aims: The relationship between Runt-related transcription factor 3 (RUNX3) gene inactivation and various solid tumors has been reported; however, little information is available about RUNX3 in thyroid cancers., Methods: We evaluated the DNA methylation of RUNX3 in 13 papillary thyroid cancer tissues and four thyroid cancer cell lines. Additionally, using reverse transcriptase-polymerase chain reaction, we analyzed RUNX3 gene expression in several thyroid cancer cell lines after treating with the demethylating agent 5-aza-2'-deoxycytidine (DAC)., Results: RUNX3 was hypermethylated in many thyroid cancer cell lines and in 10 of the 12 papillary thyroid cancer tissues. Treatment with DAC increased the expression of RUNX3 in some thyroid cancer cell lines., Conclusions: We suggest that RUNX3 is associated with thyroid carcinogenesis, and RUNX3 methylation is a potentially useful diagnostic marker for papillary thyroid cancer.

Published
2012
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