1. Cigarette Smoking-Induced Acute Eosinophilic Pneumonia: A Case Report Including a Provocation Test
- Author
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Ki-Up Kim, Yang Ki Kim, Young Mok Lee, Dong Won Kim, Jung Hwa Hwang, Soo-Taek Uh, and Gene Hyun Bok
- Subjects
Male ,Spirometry ,medicine.medical_specialty ,Adolescent ,government.form_of_government ,Provocation test ,Case Report ,Bronchial Provocation Tests ,Pulmonary function testing ,Internal medicine ,medicine ,Humans ,Pulmonary Eosinophilia ,Intensive care medicine ,Lung ,medicine.diagnostic_test ,business.industry ,Smoking ,General Medicine ,respiratory system ,Provocation Test ,respiratory tract diseases ,Bronchoalveolar lavage ,medicine.anatomical_structure ,Acute eosinophilic pneumonia ,Acute Disease ,government ,Sputum ,medicine.symptom ,business ,Acute Eosinophilic Pneumonia - Abstract
The mechanism and cause of acute eosinophilic pneumonia are largely unknown. Many factors including the smoking of cigarettes have been suggested, but none have been proven to directly cause acute eosinophilic pneumonia. The authors report a case of acute eosinophilic pneumonia in a young Asian male who recently started smoking. The diagnosis was made based on his clinical course and results of chest radiography, lung spirometry, bronchoalveolar lavage, and transbronchial lung biopsies. After administration of methylprednisolone, his clinical course rapidly improved. A provocation test was designed to establish a connection between cigarette smoking and the development of acute eosinophilic pneumonia. After the provocation test, the patient showed identical symptoms, increase in sputum eosinophils, and worsening of pulmonary function. The results of the provocation test suggest that smoking may directly cause acute eosinophilic pneumonia, and support previous reports of cigarette smoking-induced acute eosinophilic pneumonia.
- Published
- 2008