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1. Acid Catalyzed Solvent Free Synthesis of New 1-Acyl-4-benzhydryl Substituted Pyrazoles.

Author

Sher, Muhammad, Ahmed, Ejaz, Kausar, Tasneem, Riaz, Nadia, Arshad, Muhammad, Sharif, Ahsan, Intisar, Azeem, Akhtar, Javeed, and Aamir, Muhammad

Subjects
PYRAZOLES, ACIDS, DIPHENYL, KETONES, HYDRAZIDES, MORTARS & pestles, MORTAR
Abstract

A convenient, cost effective and environmentally benign methodology has been developed, which delivered fourteen new 1-acyl-4-benzhyrdyl substituted pyrazole derivatives under solvent free conditions. Target compounds were synthesized in good to excellent yields simply by grinding reactants in a pestle and mortar with catalytic amount of conc. H2SO4. All the newly formed compounds were fully characterized with the help of detailed spectroscopic techniques including FTIR, NMR and GC-MS. [ABSTRACT FROM AUTHOR]

Published
2016

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