1. Lipomatous metaplasia after severe and chronic cutaneous inflammation.
- Author
-
Eyerich K, Traidl-Hoffmann C, Albert A, Kerzl R, Rombold S, Darsow U, Eberlein B, Jakob T, Ring J, and Hein R
- Subjects
- Adipose Tissue pathology, Aged, Diclofenac adverse effects, Dipyrone adverse effects, Extremities pathology, Female, Humans, Lipomatosis pathology, Metaplasia pathology, Skin pathology, Skin Diseases, Vesiculobullous chemically induced, Dermis pathology, Drug Eruptions complications, Inflammation complications, Lipomatosis etiology, Metaplasia etiology, Psoriasis complications, Skin Diseases, Vesiculobullous complications
- Abstract
A 69-year-old woman with a history of acute generalized exanthematic pustulosis (AGEP) caused by metamizole is described. Furthermore, she had suffered from an untreated psoriasis since the age of 20. After an adequate therapy of both psoriasis and AGEP, yellow-brownish, static, coalescing, lucent nodules on the thighs and upper arms became apparent. Histology of skin biopsies revealed a prominent band of mature adipocytes in the dermis. We diagnosed a lipomatous metaplasia of the dermis and hypothesize that this metaplasia occurred as a consequence of the severe and chronic inflammation of the skin., (Copyright 2008 S. Karger AG, Basel.)
- Published
- 2008
- Full Text
- View/download PDF