1. Inherited blistering diseases of the skin.
- Author
-
Fine JD, Johnson LB, and Wright JT
- Subjects
- Basement Membrane, Humans, Prognosis, Epidermolysis Bullosa Dystrophica diagnosis, Epidermolysis Bullosa Dystrophica etiology, Epidermolysis Bullosa Dystrophica genetics, Epidermolysis Bullosa Dystrophica therapy, Epidermolysis Bullosa Simplex diagnosis, Epidermolysis Bullosa Simplex etiology, Epidermolysis Bullosa Simplex genetics, Epidermolysis Bullosa Simplex therapy, Epidermolysis Bullosa, Junctional diagnosis, Epidermolysis Bullosa, Junctional etiology, Epidermolysis Bullosa, Junctional genetics, Epidermolysis Bullosa, Junctional therapy
- Abstract
Inherited epidermolysis bullosa (EB) comprises some 23 different phenotypic disorders which have as common features the presence of mechanically fragile skin and the tendency to develop blisters, erosions, and in some cases, scarring of the skin. While some forms of this disease are relatively mild, other rarer variants may prove to be life-threatening. In the past 15 years, a wealth of new information has elucidated new clinical and laboratory characteristics of specific EB subsets. In this brief review, the most important aspects of inherited EB are summarized to update the practicing pediatrician about the ever-increasing complexities being discovered about this disease.
- Published
- 1991