1. Long-term (up to 18 years) clinical and echocardiographic results of mitral balloon valvuloplasty in 531 consecutive patients and predictors of outcome.
- Author
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Fawzy ME, Shoukri M, Fadel B, Badr A, Al Ghamdi A, and Canver C
- Subjects
- Adolescent, Adult, Atrial Fibrillation mortality, Cardiac Tamponade mortality, Child, Child, Preschool, Coronary Restenosis mortality, Female, Follow-Up Studies, Humans, Hypertension, Pulmonary mortality, Kaplan-Meier Estimate, Male, Middle Aged, Multivariate Analysis, Predictive Value of Tests, Pregnancy, Pregnancy Complications mortality, Proportional Hazards Models, Young Adult, Catheterization mortality, Echocardiography, Mitral Valve Stenosis diagnostic imaging, Mitral Valve Stenosis mortality, Mitral Valve Stenosis surgery
- Abstract
Objectives: The study aim was to assess the long-term results (up to 18 years) of mitral balloon valvuloplasty (MBV) and to identify predictors of restenosis and event-free survival., Methods: The immediate and long-term results for 531 consecutive patients (mean age 31 +/- 11 years) who underwent successful MBV and were followed up for a mean of 8.5 +/- 4.8 years (range: 1.5-18 years) are reported., Results: The mitral valve area (MVA) increased from 0.92 +/- 0.17 to 1.95 +/- 0.29 cm(2) (p < 0.0001). Restenosis was 31 and 19% in patients with mitral echocardiographic score (MES) < or =8. Actuarial freedom from restenosis at 10, 15 and 18 years was 77 +/- 2, 46 +/- 3 and 18 +/- 4% and 86 +/- 2, 62 +/- 4 and 31 +/- 7% for MES < or =8, respectively (p < 0.001). Event-free survival (death, redo MBV, mitral valve replacement, NYHA class III or IV) at 10, 15 and 18 years was 88 +/- 1, 53 +/- 4, and 21 +/- 5% and 93 +/- 2, 65 +/- 5 and 38 +/- 8% for MES < or =8, respectively (p < 0.001). Multivariable Cox regression analysis identified MES >8 (p < 0.0001) and previous surgery (p = 0.043) as predictors of restenosis, and MES >8 (p < 0.0001) and baseline atrial fibrillation (p = 0.03) as predictors of combined events., Conclusion: MBV provides excellent long-term results. The baseline clinical and MES characteristics are predictors of outcome., (Copyright (c) 2009 S. Karger AG, Basel.)
- Published
- 2009
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