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Objective To identify differentially expressed genes(DEGs) in colorectal cancer and explore key pathways and genes in colorectal cancer due to the relatively high incidence of colorectal cancer. Methods The gene expression profiles GSE211496, GSE6988 and GSE29900 data sets from the gene expression comprehensive data set were selected, and the GEO2R analysis tool was used to analyze and download the relevant data. The online database miRDB and TargetScan were used to predict the target genes of the differential miRNAs in the GSE29900 data set. Then, the DEGs intersection of the three databases was taken by Wayne diagram, and the DAVID database tool was used for Gene Ontology(GO) and Kyoto Encyclopedia of Genes and Genomes(KEGG) pathway enrichment analysis. Then Protein-Protein Interactions(PPI) protein interaction tool was used for network construction and visualization by Cytoscape software. Hub gene expression was verified by The Cancer Genome Atlas(TCGA) database. Receiver operating characteristic(ROC) curve analysis was performed on Hub genes consistent with TCGA database expression using pROC package. Finally, Kaplan-Meier plotter online tool detection was used to analyze the prognosis of colorectal cancer patients. Results A total of 2 570 DEGs(p. adj<0. 01 and |log2FC|≥1) in GSE211496 dataset, 406 DEGs(p. adj <0. 01 and |log2FC|≥1) in GSE6988 dataset and 99 differentially expressed miRNAs(p. adj<0. 01 and | log2FC|≥1) in GSE29900 dataset were screened out, and 14 938 target genes of differentially expressed miRNAs were predicted. A total of 30 target genes were obtained by overlapping the target genes with DEGs. The results of KEGG pathway showed that the target genes were mainly enriched in vascular smooth muscle contraction and mineral absorption pathways. The top 10 Hub genes were screened from the PPI network by connectivity. The TCGA database of Hub genes verified that MYL9, ACTG2, AGT and PDGFRA were consistent with the expression of GSE211496 data set. Analysis of the four Hub genes for the diagnosis of colorectal cancer showed that gene AGT(AUC=0. 901, 95%CI 0. 868-0. 933) was positively correlated with the prediction of colorectal cancer, while gene MYL9(AUC=0. 820, 95% CI 0. 757-0. 884), gene ACTG2(AUC=0. 855, 95%CI 0. 802-0. 908) and gene PDGFRA(AUC=0. 815, 95%CI 0. 772-0. 858) were negatively correlated with the prediction of colorectal cancer. Gene MYL9, ACTG2 and PDGFRA had certain accuracy in the diagnosis of colorectal cancer, and gene AGT had high accuracy in the diagnosis of colorectal cancer. Kaplan- Meier survival analysis showed that low expression of PDGFRA, ACTG2 and MYL9 indicated better prognosis, and the differences were statistically significant(P <0. 05). Conclusion In this study, four genes were screened and identified as hub genes in colorectal cancer by bioinformatics analysis. These genes include PDGFRA, ACTG2, MYL9 and AGT, which will provide some new directions for colorectal cancer research. [ABSTRACT FROM AUTHOR]

Hypoxia-inducible factors (HIFs) are key protein members in tumour acute and chronic hy poxia response with special biological functions. HIFs are highly expressed in a variety of tumors, including hepatocellular carcinoma (HCC), and can promote the epithelial-mesenchymal transition (EMT) process of tumor cells. HCC has the characteristic of typical aggressive growth, which are closely associated with EMT. The Notch signaling pathway is a highly conserved signal transduction pathway in biological evolution, which is involved in the EMT process of cells and plays an important role in the promotion of tumour growth and migration by HIFs. HIFs may exert effects directly or indirectly on tumor cell EMT processes including HCC through the Notch signaling pathway. This article provided a brief review of the regulatory effects of HIFs on tumor cell EMT, especially on HCC EMT, and the possible role of Notch signaling pathway in this process. [ABSTRACT FROM AUTHOR]

Objective To evaluate the effect of surgical treatment on left and right ventricular function in patients with primary aldosteronism (PA) by ultrasonic spot tracking imaging (STI). Methods The clinical data of 55 PA patients who underwent surgical treatment (the surgery group) and 55 PA patients who underwent drug treatment (the non-surgery group) matched with age, sex and course of hypertension from October 2018 to February 2022 in the Department of Endocrinology of this hospital were retrospectively analyzed. The clinical characteristics and echocardiographic data were compared between the two groups, as well as the differences of left and right ventricular global longitudinal peak systolic strain (LVGLS, GRVLS) between the two groups.Results The postoperative blood pressure and plasma aldosterone concentrations (PAC) were decreased, and serum potassium level was increased in the surgery group.Compared with the non-surgery group, the absolute values of LVGLS and GRVLS in the surgery group were significantly increased, and the differences were statistically significant (P <0.05). Conclusion High PAC will lead to subclinical damage to left and right ventricular function.Surgical treatment can correct hypertension, high PAC and hypokalemia in most primary aldosteronism patients, and reverse the subclinical damage of the left and right ventricular function.Early and timely diagnosis and treatment of PA can improve patient outcomes. [ABSTRACT FROM AUTHOR]

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目的 观察情志护理在火龙灸治疗气滞血瘀型原发性痛经患者中的应用效果。方法 选取 2021 年 7-12 月该院妇科门诊就诊的80例气滞血瘀型原发性痛经患者作为研究对象, 将其随机分为观察组和 对照组, 各40例。其中对照组实施火龙灸+常规护理, 观察组在对照组基础上实施情志护理, 比较 2 组患者护 理前后临床疗效, 腹痛程度, 乳房胀痛程度, 心理状况, 生活质量, 护理满意度。结果 观察组患者视觉模拟评 分法, 抑郁自评量表, 焦虑自评量表评分均明显低于对照组, 差异均有统计学意义(P<0.05)。观察组护理 5个 疗程后生活质量各项评分均明显高于对照组, 差异均有统计学意义 (P<0.05)。观察组护理后临床治疗有效率 (100.0%) 明显高于对照组 (82.5%), 差异有统计学意义(P<0.05)。观察组满意度 (97.5%) 明显高于对照组 (80.0%), 差异有统计学意义(P<0.05)。结论 情志护理在火龙灸治疗气滞血瘀型原发性痛经患者疗效明 显, 有利于提高患者身心舒适度, 改善负面情绪, 提高生活质量及护患满意度, 值得临床推广和应用. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

阴道加德纳菌 (GV) 可存在于儿童和健康男女的肛门、直肠中,也是妊娠妇女阴道内菌群的一 部分。在阴道内乳酸杆菌大量减少的时候,拟杆菌和 GV 等厌氧菌就会大量增殖,从而引起非特异性阴道病, 临床表现为白细胞浸润和炎性病变。GV 通常为阴道内的致病菌,在临床上常会引起细菌性阴道病,然而在女 性阴道外发生的阴道 GV 感染十分罕见。该文报道了 4 例由 GV 引起的孕产妇血流感染病例,供临床医生 参考。 [ABSTRACT FROM AUTHOR]

Objective To explore the effect of modified catheter fixation in patients after lumbar cisterna drainage. Methods The patients who underwent lumbar cisterna drainage in the neurosurgery department of the hospital were randomly divided into the observation group and the control group according to the time order of catheterization. Among them, 74 patients with lumbar cistern drainage from August to January 2022 were selected as the observation group, and the drainage tube was fixed by the "five-step method",and 74 patients with external lumbar cistern drainage from January 2021 to July 2021 were selected as the control group, and the traditional catheter fixation method was given. The incidence of catheter removal, tube blocking, cerebrospinal fluid leakage, and patient satisfaction were compared between the two groups. Results There were statistically significant differences in catheter removal (χ~2=5. 781,P＜0. 05),tube blocking (χ~2=4. 015,P＜0. 05),cerebrospinal fluid leakage (χ~2=4. 132,P＜0. 05) and satisfaction (χ~2=4. 812,P＜0. 05) between the two groups. Conclusion The "five-step method" to fix the catheter after external drainage of lumbar cistern can reduce the occurrence of adverse events such as catheter detachment, catheter blockage and cerebrospinal fluid leakage after operation, and improve the quality of clinical nursing. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

颅内蛛网膜囊肿(IACs)分为先天性与后天性,大多数不能自行消散,且无明显临床表现。不同 位置的IACs症状稍有不同,其严重程度与囊内压力显著相关。对于IACs的治疗方式,目前尚存在争议,神经 内镜手术治疗因其住院时间短、手术创伤小、中出血少、长短期并发症少成为目前首选治疗方式。该文对IACs 的相关研究进行了综述,旨在为IACs的临床诊疗提供一定帮助。 [ABSTRACT FROM AUTHOR]

目的 探讨以病例为基础 (CBL) 联合 Sandwich 教学法在内分泌科住院医师规范化培训(住 培)中的应用效果。方法 选取 2021 年 8-12 月该科室住培医师 42 名作为研究组,同时选取 2020 年 6-12 月 该科室住培医师 52 名作为对照组。对照组采用传统教学模式,研究组采用 CBL 联合Sandwich教学模式,比较 2组综合能力考核成绩和教学满意度评分。结果 2 组综合能力考核成绩比较,差异有统计学意义(P<0.05)。 研究组自主学习能力、临床思维能力、文献查阅能力及教学模式满意度评分均高于对照组,差异有统计学意义 (P<0.05)。2组医患沟通能力、团队协作能力满意度评分比较,差异无统计学意义 (P>0.05)。结论 CBL 联合 Sandwich 教学模式可使临床医学理论和实践衔接更加紧密,可提高住培医师综合能力和教学满意度。 [ABSTRACT FROM AUTHOR]

急性氮氧化物中毒主要通过直接和间接肺损伤引起全身炎症反应及免疫功能紊乱,导致化学 性肺炎、急性呼吸窘迫综合征 (ARDS) 等发生。其中毒损伤机制复杂,一旦继发 ARDS,死亡率明显上升。作者 通过体外膜肺氧合成功救治1例急性氮氧化物中毒致重度 ARDS 的危重患者,取得良好效果。通过分析此病 例,总结氮氧化物中毒的损伤机制及 ECMO 的启动时机和管理经验,得出 ECMO 能快速纠正重度氮氧化物中 毒患者的顽固性低氧血症,提高生存率。 [ABSTRACT FROM AUTHOR]

Objective To investigate the cognition of human papillomavirus（HPV）and its vaccine among clinical and nursing interns,and to explore the vaccination willingness and its related influencing factors.Methods A total of 1 020 interns from clinical related majors and nursing majors from four general hospitals in Nanjing were randomly surveyed in December 2020.A total of 1 020 questionnaires were sent out and 1 009 valid questionnaires were collected.A self-designed questionnaire was used to conduct an anonymous survey.Results The awareness rate of HPV,HPV vaccine and cervical cancer were 36.6%,58.0%,and 56.1%seperately.The common routes of transmission of health education were school education（44.2%), official brochures（37.5%）and media propaganda films（36.8%）.Females were more likely to know about HPV and its vaccines.Vaccine safety（65.9%）,effectiveness（63.4%）,duration of immunity（62.2%）and vaccine price（50.7%）were common subjective factors affecting vaccination.The vaccination willingness rate was 85.2%.Multivariate logistic regression analysis showed that HPV awareness,cervical cancer caused by persistent viral infection,and HPV vaccine awareness were the important influencing factors of vaccination willingness.Conclusion The awareness rate of cervical cancer,HPV and HPV vaccine among clinical and nursing interns are low but the willingness to vaccination is high.The cognitive level is an important influencing factor of vaccination willingness. [ABSTRACT FROM AUTHOR]

目的 通过对60~83岁2型糖尿病患者进行认知评估,探讨2型糖尿病患者轻度认知功能障 碍的危险因素。方法 选取2018年8月至2019年8月该院2型糖尿病合并轻度认知功能障碍组94例患者,2 型糖尿病认知功能正常组98例患者。收集2组患者年龄、性别、文化程度、糖尿病年限、体重指数、糖化血红蛋 白等基本资料,再运用t 检验、χ² 检验、Spearman相关分析及二分类logistic逐步回归分析方法探讨老年2型 糖尿病患者认知功能障碍的危险因素。结果 2组性别、受教育年限、糖尿病病程、糖化血红蛋白比较,差异有 统计学意义(P <0.05)。二分类logistic逐步回归分析提示2型糖尿病患者受教育年限、糖化血红蛋白是其认 知功能障碍的相关危险因素(P <0.05)。结论 2型糖尿病患者轻度认知功能障碍受多种因素影响,丰富患者 知识、管理好患者血糖可能预防患者发展成为轻度认知功能障碍。 [ABSTRACT FROM AUTHOR]

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Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

[摘 要] 二级集中救治定点医院承担了大量新型冠状病毒肺炎防治基础工作,护理管理工作面临自我防护、人力资源、物 资储备及护理管理重点转移等诸多困难和挑战。因此,护理部应根据疫情特点快速调整应对措施,不断完善护理应急管理体系及 组织架构,从落实全员培训、建立三级应急梯队、合理管控防护物资、优化管理流程及工作模式、全程规范管理患者、激励关爱一线 护士等方面着手,充分发挥管理职能,保障了疫情防控各项工作的顺利进行. [ABSTRACT FROM AUTHOR]

要] 目的 优化急救护理联合优质护理在急性左心衰竭(ALVF)患者中的应用效果。方法 选取2018年1月至 2019年12月该院收治的75例ALVF患者,按照顺序编码法将其分为对照组(37例)和观察组(38例)。对照组采用常规急救护 理,观察组在对照组基础实施优化急救护理联合优质护理,比较2组救治效果及家属满意度。结果 2组急救护理总满意度比 较,差异有统计学意义(P <0.05)。2组在急救时间、住院时间、抢救后日常生活活动能力评分、抢救成功率、病死率和并发症发生 率等方面比较,差异均有统计学意义(P <0.05)。结论 在ALVF患者的临床急救中,应用优化急救护理联合优质护理可有效缩 短急救时间,提高抢救成功率,降低病死率和并发症发生率,缩短住院时间,促进患者术后自我生活能力的提升,提高患者家属满 意度。 [ABSTRACT FROM AUTHOR]

Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

宫颈恶性肿瘤除了常见的鳞癌、腺癌外，还有一些特殊病理类型， 如宫颈神经内分泌癌、宫颈淋巴痐、宫颈黑色素 瘤、宫颈肉瘤及宫颈透明细胞癌等。因为病例的罕见性， 目前尚无指南对这部分宫颈癌冶疗方案做出规范。该又回顾性分析了关 于宫颈神经内分必癌、宫颈淋巴疮、宫颈黑色素瘤治疗方式的文献，发现其恶性程度较高， 冶疗方式存在争议， 多借鉴发生于其他 器官相应病理类型的治疗方案，但预后相对较差，靶向冶疗及免疫冶疗的发展可能是这部分患者未来的新希望。 [ABSTRACT FROM AUTHOR]

目的 研究无缝隙护理理念在腰椎手术患者术后护理中的临床效果。方法 选取该院2016年1月至2019年7月收治并行开放式腰椎手术的腰间盘突出患者81例作为研究对象。观察组（39例）在给予常规护理手段的基础上采用无缝隙护理理念指导护理措施。对照组（42例）采用常规护理。比较2组术后恢复情况，术后并发症及不良事件发生率，术前及术后生化学指标、生活质量和应激状态。结果 观察组在术后首次通气、术后视觉模拟评分法(VAS)评分、术后首次下床时间、住院时间、肺部和切口感染、术后便秘、深静脉血栓（DVT）发生率等方面均低于对照组，差异均有统计学意义（P＜0.05）。2组在术后腰椎神经功能恢复量表（JOA）评分和术后非计划拔管、脑脊液瘘率方面比较差异均无统计学意义（P＞0.05）。术前，2组在白细胞计数、前清蛋白、血小板计数比值(RPR)及中性粒细胞比值(NEUTR)方面比较差异均无统计学意义（P>0.05）。术后，观察组在白细胞计数、前清蛋白及NEUTR方面的变化幅度低于对照组，差异均有统计学意义（P＜0.05），但2组在RPR变化上比较差异均无统计学意义（P>0.05）。术前，2组在生活质量及应激反应方面比较差异均无统计学意义（P>0.05）；术后，观察组生活质量及应激反应变化优于对照组，差异均有统计学意义（P＜0.05）。结论 无缝隙护理管理可加快腰椎手术患者的术后恢复，缩短住院时间，对患者短期生活质量的恢复具有促进作用。 [ABSTRACT FROM AUTHOR]

Objective To understand and analyze the medication rule among the outpatients with dissociative[conversion] disorders. Methods The information in 174 cases of clinically diagnosed as dissociative[conversion] disorders(ICD 10 coding F44) was collected from the hospital information system (HIS) database in a psychiatric hospital from July 22, 2018 to July 22, 2019 and their situation such as medication, drug category, dose, frequency and combined medication was statistically analyzed. Results Of 174 cases, 164 cases(94.25%) were females, 85 cases(48.85%) were 35-55 years old, its proportion was the highest. One hundred and fifty six cases (89.66%) received the medication treatment, among them, the top three of use frequencies were magnesium valproate [55(35.26%)], olanzapine [53(33.97%)] and quetiapine [36(23.08%)]. Based on the pharmacological property, the top three of use frequency were antipsychotics in 132 cases(84.62%), sedative hypnotics and antianxietics in 77 cases(49.36%) and mood stabilizers in 69 cases(44.23%). The combined use frequency of antipsychotic drugs and mood stabilizers was the highest and the top three combinations of combined frequency were valproate + quetiapine, valproate + olanzapine and valproate + risper idone. Conclusion The drugs for treating dissociative[conversion] disorders are dominated by the antipsychotic drugs. The combination use of antipsychotics and mood stabilizers is common. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To investigate the genotypes and allele frequency distribution situation of four non-synonymous single nucleotide polymorphisms（SNPs）loci rs9658667（A/G），rs9658668（T/C），rs9658669（A/G）and rs729940（T/C）at the 7th exon regions of chromograin A among Chinese Han population in Chongqing area. Methods The SNP of 4 loci at the 7th exon regions of chromograin A among 218 Han nationality people of Chongqing area were detected by using polymerase chain reaction and target fragment gene sequencing techniques. Then the results were compared with those of populations in other countries．The allele frequencies were compared with the data on NCBI on other ethnic groups.Results The minimal allele frequencies（MAF）of rs9658667（A/G），rs9658668（T/C），rs9658669（A/G）and rs729940（T/C）were e 0.048，0.000，0.000 and 0.186，respectively；comparing the population in Chongqing area with the populations in other countries and areas，the poly-morphisms distribution of rs9658667（A/G）had a certain difference，its mutation rate was significantly higher than that in Ke-nya population（P=0.001）；the loci of rs9658668（T/C）and rs9658669（A/G）ha dno mutation；the mutation rate of rs729940（T/ C）was the highest in 4 loci，which had statistical difference compared with the Nigeria population.Conclusion The polymor-phism distribution of 4 loci at the 7th exon of Chromograin A gene has a certain regional characteristic. [ABSTRACT FROM AUTHOR]

目的探究颈椎前路手术患者术后发生肺部感染的病原菌分布特点及对肺功能的影响，以期为临床治疗提供参考。方法选取2015年1月至2019年12 月该院收治的诊断为颈椎病并行手术治疗患者125例。将术后出现肺部感染患者设为观察组（39例），术后无肺部感染患者设为对照组（86例）。分析观察组患者痰液中病原菌分布情况，并对比2组患者术后肺功能、动脉血气分析及全身应激状态。结果观察组患者痰液中共分离病原菌39株，其中革兰阳性菌21株（53.85%），以肺炎链球菌［25.64%（10/39）］、D型溶血性链球菌［7.69%（3/39）］、表皮葡萄球菌［7.69%(3/39)］为主；革兰阴性菌17株（43.59%），以鲍曼不动杆菌［15.38%（6/39）］、肺炎克雷伯菌［12.82%（5/39）］为主；真菌1株（2.56%）。观察组患者术后用力1秒呼气量、呼气高峰流量、用力1秒呼气量/用力肺活量、动脉血氧分压、动脉血二氧化碳分压均较对照组明显降低，差异均有统计学意义（P＜0.05）。观察组患者术后丙二醛（MDA）、白细胞介素-6（IL-6）水平均明显高于对照组，差异均有统计学意义（P＜0.05）。观察组患者动脉氧血分压与MDA、IL-6均呈负相关（r=-0.881、-0.806，P＜0.01），动脉血二氧化碳分压与MDA、IL-6也均呈负相关（r=-0.882、-0.858，P＜0.01）。结论颈椎前路手术患者术后肺部感染后可显著抑制肺通气及气体交换功能，且加重患者全身应激状态，应给予重点预防。 [ABSTRACT FROM AUTHOR]

目的 对目标性监测多重耐药菌———耐碳青霉烯肺炎克雷伯菌 (CRKP) 检出增加进行预警分析积极干预并积 累经验。方法 对 2018 年 1 季度该院检出 CRKP 的 17 例患者进行病例回顾性调查了解患者基本情况、有无医院内感染病例、 耐药性等,以期采取相应预防控制措施。结果 全院共检出 CRKP 22 株共 17 例患者,菌株检出率为 17.74%(22/124)。科室分 布为重症监护病房 (ICU)13 例,其中 5 例患者发生医院内感染, 8 例患者为社区感染;普通科室共 4 例,其中1例患者发生医院内 感染, 3 例患者为社区感染。标本分布为痰标本占 63.64%(14/22), 尿液标本占 27.27%(6/22), 其他占 9.09%(2/22)。甲氧苄 啶/磺胺甲基异噁唑在 ICU 和普通科室、医院内感染和社区感染的耐药率均最低(<30.00%), 普通科室头孢唑林耐药率较低,为 57.14%, 医院内感染四环素耐药率为 50.00%, 其余各组均大于 70.00%, 甚至全耐药;医院内感染和社区感染、ICU 和普通科室 耐药率比较,差异均无统计学意义 (P >0.05)。结论 该院无短时间内发生 3 例以上同种同源医院内感染病例现象,不考虑医院 内感染暴发情况,但 CRKP 检出增加,尤其 ICU 需采取综合措施加强多重耐药菌防控工作。 [ABSTRACT FROM AUTHOR]

目的分析预防性肠内营养护理对重症患者肠内营养性腹泻的预防效果。方法2017年10月至2018年9月于该院接受肠内营养治疗的重症患者87例，采用随机数字表法分为对照组（44例）、干预组（43例），对照组给予常规肠内营养干预，干预组给予预防性肠内营养护理干预，比较护理干预效果。结果干预组患者营养状况相关指标水平高于对照组（P＜0.05），会阴皮肤评估评分、腹泻发生率、机械通气时间、住院时间低于对照组（P＜0.05），护理满意度高于对照组（P＜0.05）。结论对重症患者采取预防性肠内营养护理干预，可有效改善患者营养状况，降低腹泻发生率，有助于促进患者康复。 [ABSTRACT FROM AUTHOR]

Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

目的 采用直接观察法和隐蔽观察法调查医护人员手卫生，以评估真实手卫生情况。方法 2017 年 4 季度采用直接观察法和隐蔽观察法对该院临床科室医生、护士、实习医生、实习护士进行手卫生调查，对所得手卫生依从率进行比较分析。结果 直接观察法调查的手卫生依从率［88.25%（368/417）］明显高于隐蔽观察法［62.00%（780/1 258）］，差异有统计学意义（P<0.01）；隐蔽观察法观察对象中实习护士和护士手卫生依从率较高,分别为 73.37%（237/323）、61.34% (514/838)，医生和实习医生的手卫生依从率较低,分别为28.57%（16/56）、31.71% (13/41)；直接观察法观察对象中护士手卫生依从率最高,为 91.95% (217/236)，实习医生手卫生依从率最低,为 72.50% (29/40)，各类医护人员不同观察法手卫生依从率比较，差异均有统计学意义（P<0.05）；手卫生 5 个时刻中接触患者前和接触患者周围环境后手卫生依从率相对较低。结论 采用适当的观察方法调查手卫生依从性，更能够了解实际情况，以期采取合适的措施加强手卫生，降低医院感染率及预防医院感染暴发。 [ABSTRACT FROM AUTHOR]

目的探讨跨理论模型健康教育护理在慢性阻塞性肺疾病患者中的应用效果。方法选取2017年9月至2018年6月在该院治疗的慢性阻塞性肺疾病患者102例。按随机数字表法分为对照组50例和观察组52例,对照组接受常规健康教育,观察组采用基于跨理论模型的健康教育。对比2组患者干预前及干预后的生活质量及患者的临床表现。结果与对照组相比,观察组的临床表现消失时间较短,差异有统计学意义(P<0.05);干预后,观察组社交能力、精神状态等生活质量均优于对照组,且满意度高于对照组,差异均有统计学意义(P<0.05)。结论跨理论模型健康教育护理不仅促进了慢性阻塞性肺疾病患者的身体恢复,也提高了患者的生活质量。 [ABSTRACT FROM AUTHOR]

Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To understand the level of plasma homoeysteine(Hey) in health eheek-up populations and to observe the eurative effeet of folate intervention on hyperhomeeysteinemia and enalapril and folie aeid intervention on H-type hypertension. Methods 10 400 healthy individuals undergoing physieal examination in the physieal examination eenter of the First Afiliated Hospital of Ganan Medical College from January to December 2013 were selected as the research subjects. The Hey level was detected and the simple hyperhomeeysteinemia and H-type hypertension were screened and the intervention therapy was conducted. Among them, 100 cases of simple hyperhomeeysteinemia were selected and given the folie aeid therapy#200 eases of H-type hypertension were divided into the two groups and respectively given the interventional therapy of enalapril combined with folie aeid or enalapril folie aeid (fixed compound) intervention therapy. Plasma Hey was re-cheeked and sitting blood pressure was measured in 1, 2, 3 months of treatment. Results Among 10 400 eases of healthy examination population, high Hey accounted for 23.08=(2 400/10 400), in which simple hyperhomeeysteinemia was 8.78%(913/10 400), H-type hypertension was 14.30= (1 487/10 400). Plasma Hey level in simple hyperhomeeysteinemia patients was decreased after 1, 2 and 3 months of folie aeid intervention therapy, the differences were statistically significant(P<0.05 or 0.01). Plasma Hey and blood pressure level after enalapril combined with folie aeid intervention therapy or enalapril folie aeid (fixed compound) intervention therapy in the H-type hypertension patients were decreased compared with before treatment, the differences were statistically significant(P<0.05 or 0.01 ); and the differences between two methods of Hey and blood pressure levels had no statistically significance (P>0.05). Conclusion The higher proportion of simple hyperhomeeysteinemia and H-type hypertension were sereened out among the physieal examination population. It is suggested that the routine physieal examination should pay attention to the Hey level detection, which has important significance for screening hyperhomeeysteinemia, early finding H-type hypertension and conducting the early folie aeid intervention therapy. [ABSTRACT FROM AUTHOR]

目的 探讨整形外科原则和技术在面部人咬伤早期临床处理中的应用.方法 回顾性分析2008年1月至2016年11月该科对17例面部人咬伤患者进行早期清创和Ⅰ期整复缝合手术治疗的临床资料.结果 本组17例面部人咬伤患者施行清创美容整复缝合,14例患者均Ⅰ期愈合良好,且无并发症发生,3例患者出现不同程度感染,经换药或Ⅱ期清创缝合愈合.Ⅰ期愈合者伤口瘢痕达到整形美容要求,整复效果满意.结论 对面部人咬伤创面早期彻底清创,并运用整形外科原则和技术对Ⅰ期进行创面修复,具有积极临床意义. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

目的 探讨延续护理在心脏瓣膜置换术患者恢复治疗中的作用。 方法 将该院2013年6月至2015年10月收治的112例心脏瓣膜置换术后患者随机分为观察组和对照组，各56例。对照组患者住院期间进行常规健康教育、出院指导及出院后每月电话随访；观察组在常规组的基础上从出院后1周开始至3个月，通过短信进行延续护理，实行个性化指导，向患者发送健康知识、督促正确用药、调理生活饮食，及时解答疑问，帮助其解决恢复期遇到的突发问题。比较两组患者术后3个月抗凝知识知晓程度、抗凝用药依从性及不良反应发生率。 结果 观察组患者对心脏瓣膜置换术和抗凝知识知晓程度及对抗凝药物使用的依从性明显高于对照组，而不良反应发生率明显低于对照组，差异均有统计学意义（P＜0.01或0.05）。 结论 延续护理利于护患之间进行沟通和指导，可提高患者抗凝治疗依从性，减少不良反应发生，缓解患者的忧虑情绪，增强其战胜疾病的信心，提高患者生活质量。 [ABSTRACT FROM AUTHOR]