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Objective To summarize the clinical experiences of managing cervical lymphatic malformation with airway obstruction ( CLMAO) from prenatal assessments to postnatal interventions. Methods Retrospective analysis was conducted for clinical data of 22 hospitalized CLMAO infants from July 2015 to March 2023. Nine cases were born at our hospital while another 13 infants were transferred from other hospitals. They were assigned into two groups of early surgical treatment ( n = 6) and protocol treatment (n = 16 ). Fetal assessments, intrapartum managements and postnatal interventions were recorded. Surgical complications, duration of mechanical ventilation, length of hospital stay and other prognostic factors were compared between two groups. Results Nine infants born at our hospital were examined by prenatal magnetic resonance imaging( MRI) for assessing tracheoescphageal displacement index( TEDI) or amniotic fluid volume. Eight infants had TEDI> 12 mm or polyhydramnios. Ex-utero intrapartum treatment( EXIT) was offered for postnatal dyspnea. One case of TEDI≤ 12 mm and normal anmiotic fluid volume had dyspnea after umbilical cord clamping and underwent tracheal intubation. The accuracy of prenatal assessment for airway obstruction was 88. 9% ( 8/9). Three cases were operated in protocol treatment group. As compared with early treatment group, no significant inter-group differences existed in proportion of tracheostomy, duration of mechanical ventilation or length of hospital stay. During a follow-up period of ( 6 - 39) months, there was no significant difference in cure rate or improvement rate. Conclusion Fetuses with suspected CLMAO should be evaluated for TEDI and amniotic fluid volume. As compared with early surgery, programmed therapy may obtain comparable outcomes. It offers a novel therapeutic option for CLMAO. [ABSTRACT FROM AUTHOR]

Objective To explore the risk factors of high-output stoma ( HOS ) after enterostomy in infants with necrotizing enterocolitis(NEC). Methods From July 1,2017 to June 30,2021,76 neonates undergoing enterostomy due to NEC were retrospectively reviewed. They were divided into two groups of HOS ( 푛 = 2S) and non-HOS( 푛 = 51) according to whether or not HOS occurred after enterostomy. General demographics, intraoperative findings and prognosis of two groups were compared. Univariate and multivariate Logistic regressions were utilized for examining the risk factors of HOS after enterostomy. Results Univariate analysis indicated that birth weight, gestational age, preoperative need for respiratory support, NEC stages and subtypes, corrected gestational age, operative weight and residual length of proximal enterostomy were the relevant occurring factors for postoperative HOS( 푃 < 0 .0S ). Logistic regression analysis showed that residual length of proximal enterostomy was an independent risk factor of HOS after enterostomy in NEC infants ( OR = 1. 220, 95% Cl: 1. 108 -1. 343,푃 < 0. 05). Receiver operating characteristic( ROC) curve was plotted with residual length of proximal enterostomy. Area under the curve was 0. 926 ( 95 % Cl :0. 849 - 1. 000,푃 < 0. 05 ) while the sensitivity and specificity were 92% and 74% . When residual length of proximal enterostomy was 86. 5 cm, the sensitivity and specificity were 84% and 96% of HOS, indicating that it was an excellent predictor for HOS in NEC infants. Conclusion HOS is prone to occur after enterostomy in NEC infants and residual length of proximal enterostomy is an independent risk factor and an excellent predictor for HOS in NEC infants after enterostomy. [ABSTRACT FROM AUTHOR]