1. Anatomical factors triggering platypnea-orthodeoxia in adults.
- Author
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Sanikommu V, Lasorda D, and Poornima I
- Subjects
- Age Factors, Aged, Aging, Aorta physiopathology, Cardiac Catheterization instrumentation, Diaphragm physiopathology, Dyspnea pathology, Dyspnea physiopathology, Echocardiography, Transesophageal, Female, Foramen Ovale, Patent diagnostic imaging, Foramen Ovale, Patent physiopathology, Heart Septal Defects, Atrial diagnostic imaging, Heart Septal Defects, Atrial physiopathology, Heart Septal Defects, Atrial therapy, Hemodynamics, Humans, Hypoxia pathology, Hypoxia physiopathology, Magnetic Resonance Imaging, Male, Paralysis pathology, Paralysis physiopathology, Risk Factors, Septal Occluder Device, Severity of Illness Index, Treatment Outcome, Aorta pathology, Diaphragm pathology, Dyspnea etiology, Foramen Ovale, Patent complications, Heart Septal Defects, Atrial complications, Hypoxia etiology, Paralysis complications
- Abstract
Right to left shunting through a patent foramen ovale (PFO) or atrial septal defect (ASD) can cause platypnea-orthodeoxia even in a setting of normal pulmonary artery pressures. However, the late onset of symptoms despite the congenital origin of the anatomical defects is not well understood. We report a case series of patients presenting with dyspnea and orthodeoxia who developed right to left shunting as a result of associated anatomical changes that occur with aging such as tortuosity and elongation of the aorta. We propose that these acquired anatomical changes can favor right to left shunting in the setting of congenital abnormalities, therefore explaining the late onset of symptoms.
- Published
- 2009
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