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Your search keyword '"Vincent Cussac"' showing total 2 results
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2 results on '"Vincent Cussac"'

1. Lymphoplasmacytic lymphoma or multiple myeloma: immunoglobulins may lead to misdiagnosis

Author

Johann Rose, Sabine Defasque, Jonathan Farhi, Anne Besançon-Bergelin, Vincent Cussac, Jérôme Debus, Fabienne Pineau-Vincent, Pierre Lemaire, Habib Ghnaya, Nathalie Denizon, Kamel Laribi, and Mustafa Alani

Subjects
Paraproteinemia, Pathology, medicine.medical_specialty, Paraproteinemias, Immunoglobulins, Plasma cell, Malignancy, Immunophenotyping, Lymphoplasmacytic Lymphoma, Diagnosis, Differential, medicine, Humans, Diagnostic Errors, Multiple myeloma, business.industry, Waldenstrom macroglobulinemia, General Medicine, Middle Aged, medicine.disease, medicine.anatomical_structure, Female, Waldenstrom Macroglobulinemia, Differential diagnosis, Multiple Myeloma, business
Abstract

We report here a case of lymphoplasmacytic lymphoma with IgA paraproteinemia and a case of concomitant Waldenström macroglobulinemia and monoclonal gammapathy of unknown significance. These rare cases show that the isotype of a monoclonal immunoglobulin does not allow to foresee every time the underlying pathology. Clinical data and medical imaging are essential. From a biological point of view, additional analysis such as immunophenotyping, cytogenetics and molecular biology are required in addition to the cytological features in order to make an accurate differential diagnosis between lymphoid and plasma cell malignancy.

Published
2018

2. A case of EDTA-related in vitro platelet degranulation

Author

Marinela Sisiroi, Jérôme Debus, Fabienne Pineau-Vincent, Vincent Cussac, and Pierre Lemaire

Subjects
Blood Platelets, medicine.medical_specialty, Cell Degranulation, Gray Platelet Syndrome, Gastroenterology, Gray platelet syndrome, Diagnosis, Differential, Platelet degranulation, Internal medicine, medicine, Humans, Platelet, Diagnostic Errors, Edetic Acid, Aged, business.industry, Anticoagulants, General Medicine, medicine.disease, In vitro, Blood film, Grey platelets, Female, Differential diagnosis, Artifacts, business
Abstract

A 71 year-old woman is admitted to Le Mans hospital center for management of a chronic skin lesion. She has no personal nor familial bleeding history and does not take any medication. In peripheral blood collected with EDTA (ethylene diamine tetra-acetate), the platelet count is elevated and the blood film shows uniformly grey platelets. In sodium citrate-collected blood, platelets show no abnormality. We describe an EDTA-related artifact that is not to be mistaken for grey platelet syndrome.

Published
2017

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