Search

Nephrotic syndrome without haematuria following the sequelae of the infection is uncommon. The present case report describes nephrotic syndrome following varicella infection, without haematuria and hypertension in a 21-year-old young adult. The patient presented with four weeks history of fever, swelling of both feet and facial puffiness. General physical examination revealed vesicular lesions with skin crusts present on the face, trunk and extremities, Blood Pressure (BP)-110/70 mmHg, bilateral pedal oedema. Systemic examination was unremarkable. Laboratory data showed nephrotic range proteinuria, hypoalbuminaemia. Varicella Zoster Virus (VZV) was detected in blood through Polymerase Chain Reaction (PCR). Renal biopsy confirmed the diagnosis. Thus, viral glomerulopathies should be considered in patients following infection. [ABSTRACT FROM AUTHOR]

We report a young male of autosomal recessive limb girdle muscular dystrophy (LGMD) with positive family history presented with gradual onset proximal muscle weakness in all four limbs since eight years and thinning of shoulders, arms and thighs. Neurological examination revealed atrophy of both shoulders with wasting of both deltoids thinning of thighs and pseudo hypertrophy of both calves, hypotonia in all four limbs. Gower's sign was positive. Winging of scapula was present. Power was 3/5 at both shoulders, 4/5 at both elbows, 5/5 at both wrists, 3/5 at both hip joints, 3/5 at both knees, 5/5 at both ankles. All deep tendon reflexes and superficial reflexes were present with plantars bilateral flexors. Electromyography (EMG) showed myopathic pattern. He had elevated creatinine phosphokinase levels and muscle biopsy findings consistent with muscular dystrophy. [ABSTRACT FROM AUTHOR]