1. Recurrent Drug-induced Liver Injury Caused by the Incidental Readministration of a Kampo Formula Containing Scutellariae Radix
- Author
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Tatsuya Nogami, Hideyuki Kitahara, Hidetoshi Watari, Makoto Fujimoto, Yoshiyuki Kimbara, Yutaka Shimada, Keiichiro Kita, and Hiroki Misawa
- Subjects
Drug ,medicine.medical_specialty ,media_common.quotation_subject ,Kampo ,Case Report ,03 medical and health sciences ,0302 clinical medicine ,Internal medicine ,Scutellariae radix ,Internal Medicine ,medicine ,Humans ,shosaikoto ,Prescribed drugs ,adverse drug event ,Aged ,media_common ,Liver injury ,business.industry ,General Medicine ,medicine.disease ,Discontinuation ,Kampo medicine ,Adverse drug event ,030220 oncology & carcinogenesis ,saikokeishikankyoto ,Female ,030211 gastroenterology & hepatology ,Medicine, Kampo ,Chemical and Drug Induced Liver Injury ,Scutellariae Radix ,business ,drug-induced liver injury ,Drugs, Chinese Herbal ,Scutellaria baicalensis - Abstract
A 67-year-old woman experiencing coughing visited a clinic and was prescribed drugs, including shosaikoto extract, for 4 days. She subsequently suffered from liver injury, but her condition improved after the discontinuation of all medications. Approximately 1 year later, she experienced fatigue, consulted another clinic, and received saikokeishikankyoto extract for 21 days. She subsequently suffered liver injury again. Both shosaikoto and saikokeishikankyoto contain Scutellariae Radix. This case is thought to be one of recurrent drug-induced liver injury caused by the incidental readministration of a Kampo formula containing Scutellariae Radix. An awareness of adverse drug events caused by Kampo formulas, especially those containing Scutellariae Radix, is essential.
- Published
- 2018
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