48 results on '"Sakurai, Takashi"'
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2. Construction of the ELISA assay to quantify Semaphorin 3A in the adult brain
3. In silico prediction of RyR1 inhibitor binding structure
4. Effects of a novel RyR2 specific inhibitor on arrhythmias in catecholaminergic polymorphic ventricular tachycardia (CPVT) model mice
5. Construction of a screening platform based on integration of in silico and biochemical experiments
6. Novel CACNA1S mutations for malignant hyperthermia enhance depolarization-induced Ca2+ release
7. Comparison of voluntary exercise and renin angiotensin inhibitor administration in a mouse model of dilated cardiomyopathy
8. Construction of the ELISA assay to quantify Semaphorin 3A in the adult brain
9. Evaluation of antiarrhythmic agents for catecholaminergic polymorphic ventricular tachycardia (CPVT) using multiple lines of RyR2-mutant mouse models
10. Therapeutic effects of voluntary wheel running on cancer cachexia-induced cardiac dysfunction: Approach from the perspective of Cardio-oncology
11. Development of a method for single-molecule imaging in the brain tissue
12. Regulation of function and metabolism of amyloid-beta precursor protein by Semaphorin3A-PlexinA signaling
13. Single-molecule imaging of synaptic molecules within the brain tissue
14. Anti-arrhythmic effects of novel RyR2 inhibitors screened from well-characterized drug library by ER Ca2+ monitoring.
15. Construction of the ELISA assay to quantify Semaphorin 3A in the adult brain
16. Establishment of reconstituted depolarization-induced Ca2+ release platform for drug discovery of skeletal muscle diseases
17. Evaluation of RyR2 inhibitors as anti-arrhythmic drugs using novel CPVT model mice
18. Potential effects of Semaphorin3A-PlexinA signaling on the function and metabolism of amyloid-beta precursor protein
19. Loss-of-function RyR2 mutations cause various types of arrhythmias through divergent abnormal Ca2+ signaling
20. Heteromeric complex formation and crosstalk between type 1 metabotropic glutamate receptor and GABAB receptor
21. Cancer cachexia-induced myocardial impairment could be improved by voluntary wheel running
22. Identification of binding site for a novel RyR1-selective inhibitor
23. Axonal targeting of TrkA-APP complex via transcytosis
24. Effects of RyR2 specific inhibitors on arrhythmia in CPVT model mice
25. Gender differences in the effect of spontaneous exercise on heart failure in DCM model mice
26. Analyses of Forming Hetero-oligomers and Regulating Signal transductions of G-Protein Coupled Receptors (GPCRs) Expressed in the Central Nervous System.
27. Characterization of novel RyR1 selective inhibitors identified by ER Ca2+ measurements
28. Sexual differences on effects of voluntary exercise on heart failure in DCM model mice.
29. Effects of a novel RyR1 inhibitor on malignant hyperthermia model mice
30. Type 1 metabotropic glutamate receptor 1 and GABA B receptor form complexes at cell membrane and mutually modulate their function
31. Voluntary wheel running improves cardiac dysfunction associated with cancer cachexia induced by human stomach cancer cell line 85As2
32. Oxidative stress-mediated neural cell death induced by nanoparticles
33. Daily voluntary exercise suppresses progression of heart failure in DCM model mice.
34. Oxidative stress-mediated cell death induced by silica nanoparticles in neural cells.
35. Voluntary wheel running may improve cardiac dysfunction in experimental mouse model of cancer-induced cachexia
36. Functional interaction and complex formation of metabotropic glutamate and GABA receptor
37. Structure development of oxolinic acid, a novel inhibitor of type 1 ryanodine receptor
38. Axonal targeting of TrkA and its interacting molecule via transcytosis
39. A novel strategy for treatment of cancer cachexia targeting the altered purine metabolism in the brain
40. Continuous inhibition of secretase regulates synapse formation
41. Therapeutic effects of voluntary wheel running on cardiac dysfunction induced by cancer cachexia
42. Therapeutic effects of ghrelin and des-acyl ghrelin on anthracycline doxorubicin-induced cardiac toxicit
43. Molecular Basis of Ca2+ Binding to the Ryanodine Receptor for Channel Activation
44. Novel strategy for treatment of cancer cachexia based on metabolic alteration in central nervous system in a mouse model
45. Discovery of novel RyR2 inhibitors as candidates for anti-arrhythmic drugs
46. Impacts of loss-of-function RyR2 mutations on Ca2+ signaling in non-cardiac and cardiac cells
47. A novel strategy for treatment of cancer cachexia targeting xanthine oxidase in the brain.
48. Complex formation and functional interaction between adenosine A1 receptor and type-1 metabotropic glutamate receptor.
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