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Your search keyword '"Yoshiro Shinozaki"' showing total 2 results
Start Over Author "Yoshiro Shinozaki" Publisher japanese circulation society
2 results on '"Yoshiro Shinozaki"'

1. Improvement by 5-Amino-4-Imidazole Carboxamide Riboside of the Contractile Dysfunction That Follows Brief Periods of Ischemia Through Increases in Ecto-5'-Nucleotidase Activity and Adenosine Release in Canine Hearts

Author

Koichi Node, Masatsugu Hori, Hidezo Mori, Masafumi Kitakaze, Seiji Takashima, Tsunehiko Kuzuya, Yoshiro Shinozaki, and Tetsuo Minamino

Subjects
medicine.medical_specialty, Adenosine, Nucleotidase activity, Physiology, Myocardial Ischemia, Ischemia, 5'-nucleotidase, chemistry.chemical_compound, Dogs, Internal medicine, Nucleotidase, Animals, Medicine, 5'-Nucleotidase, Imidazole carboxamide, business.industry, Myocardium, Hemodynamics, Riboside, Aminoimidazole Carboxamide, medicine.disease, Myocardial Contraction, Adenosine receptor, Endocrinology, Purinergic P1 Receptor Antagonists, chemistry, Reperfusion, Ribonucleosides, Cardiology and Cardiovascular Medicine, business, medicine.drug
Abstract

5-Amino-4-imidazole carboxamide (AICA) riboside increases adenosine release in ischemic myocardium, suggesting that AICA riboside improves contractile dysfunction. In 49 open-chest dogs, contractile function assessed by fractional shortening (FS) was observed 3 h after the onset of reperfusion following 15 min of occlusion of the left anterior descending coronary artery. During reperfusion, the treatment with AICA riboside increased adenosine concentration in the coronary venous blood (536±44 vs 281±21 pmol/ml at 3 min of reperfusion, p

Published
1999
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2. An increase in adenosine release contributes to the infarct size limiting effect of ischemic preconditioning

Author

Toshikazu Morioka, Takenobu Kamada, Mitsuaki Chujo, Michitoshi Inoue, Hiroshi Sato, Hidezo Mori, Koichi Node, Masatsugu Hori, Seiji Takashima, Masafumi Kitakaze, Yoshiro Shinozaki, and Tetsuo Minamino

Subjects
medicine.medical_specialty, Adenosine, Physiology, business.industry, Myocardium, Myocardial Infarction, Myocardial Ischemia, Limiting, Infarct size, Oxygen, Dogs, Coronary Circulation, Internal medicine, medicine, Cardiology, Animals, Ischemic preconditioning, Cardiology and Cardiovascular Medicine, business, medicine.drug
Published
1993
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