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A case of recurrent gfastric carcinoma (endocrine cell type) successfully treated with combination chemotherapy with divided low-dose FP therapy is reported. The patient was a 47-year-old man who underwent total gastrectomy and combined distal pancreatectomy and splenectomy in June 1995 after receiving a diagnosis of Borrmann type 2 gastric carcinoma. The overall degree of advancement was as follows: H0, P0, se, n2, and stage IIIb. The histologic diagnosis was endocrine cell carcinoma. The patient initially presented with loss of appetite and a palpable abdominal mass 18 months later. Abdominal computed tomography showed metastatic lesions in both lobes of the liver, a metastatic abdominal wall mass 3cm in diameter and located directly below the umbilicus, and a pelvic mass 4cm in diameter. The patient underwent divided low-dose FP therapy, and by the 10th course, the hepatic metastases showed complete responses, and the abdominal wall and pelvic masses showed partial responses. The patient was still in good health 2 year and 6 months after initiation of therapy. These results suggest that combination chemotherapy with divided low-dose FP therapy may be useful for the treatment of highly proliferative cancers such as endocrine cell carcinoma, which exhibits a highmalignant potential, and should be actively employed in the treatment of such cancers.

A case of cancer of the sigmoid colon in which the carcinoma prolapsed from the anus due to intussusception is reported. A 62-year-old woman was seen at the hospital because she noticed of anal bleeding and a prolapsed intestine through the anus by about 20cm after evacuation. A Borrmann type 2 type 2 tumor was noted at the head of prolapsed intestine, and was diagnosed as adenocarcinoma on biopsy. Barium enema study revealed a claw like image and a pelvic CT scan presented target sign, indicating intussusception of the intestine. An iperation was performed with a diagnosis of intussusception of the intestine headed by the sigmoid cancer. During operation, we found difficulty in repositioning the intussusception completely due to severe adhasion, and performed a sigmoydectomy with lymph node dissection (group 3) in the state of invaginated intestine. The resected material revealed a 3.5×2.5cm Borrmann type 2 tumor with the invasion depth of mp that was a moderately differentiated adenocarcinoma of n0, Ly1, V0, ow (-), aw (-), and Stage I. So far another 20 cases of cancer of the sigmoid colon prolapsed through the anus due to intussusception have been seen in the Japanese literature. These redlatively rare 21 cases including ours are discussed in terms of clinical characteristics here.