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Medicinal plants and their secondary metabolites have long been a rich source of biologically active compounds that can prevent many diseases. In this context, we investigated the antioxidant activities of the essential oil of Lavandula officinalis and tested its potency against hepatic and renal toxicity induced by hydrogen peroxide in adult male mice based on measurements of biochemical parameters, oxidative stress, and tissue damage in both organs. We proved a remarkable antioxidant power of this plant (in vitro) by correcting the harmful effects of the prooxidant (in vivo). It can be concluded that lavender is an aromatic plant capable of reducing the stress caused by reactive oxygen species. [ABSTRACT FROM AUTHOR]