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Start Over Author "David T. Connor" Publisher japan antibiotics research association
2 results on '"David T. Connor"'

1. Ambruticin (W7783), a new antifungal antibiotic

Author

G. Kanter, M. Von Strandtmann, Ann Gutt, Sidney Roemer, R. C. Greenough, Samuel M. Ringel, David T. Connor, and B. Blair

Subjects
Pharmacology, Polyangium, Myxobacteriales, Antifungal Agents, Magnetic Resonance Spectroscopy, Spectrophotometry, Infrared, biology, medicine.drug_class, Antifungal antibiotic, fungi, Antibiotics, Microbial Sensitivity Tests, AMBRUTICIN, biology.organism_classification, Mass Spectrometry, Microbiology, Lethal Dose 50, Mice, Fermentation, Drug Discovery, medicine, Animals, Myxococcales, Bacteria, Pyrans
Abstract

Ambruticin represents a new class of antibiotics isolated from a strain of Polyangium cellulosum var. firlvum, a bacterium belonging to the class Myxobacteriales. This antibiotic is a cyclopropyl-polyene-pyran acid and is active in vitro against fungi.

Published
1977
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2. Antifungal agents. 3. Chemical modification of antibiotics from Polyangium cellulosum var. fulvum. A divinylcyclopropane-cycloheptadiene rearrangement

Author

David T. Connor, Maximillian Von Strandtmann, and Sylvester Klutchko

Subjects
Pharmacology, Polyangium, Antifungal, Antifungal Agents, Chemical Phenomena, medicine.drug_class, Antifungal antibiotic, Stereochemistry, Myxococcales, Antibiotics, Chemical modification, Biology, Divinylcyclopropane-cycloheptadiene rearrangement, Chemistry, Drug Discovery, medicine, Cycloheptanes
Abstract

The thermal rearrangement of antifungal antibiotic 1, isolated from Polyangium cellulosum var. fulvum, to cycloheptadiene derivative 2 is described.

Published
1979
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