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Your search keyword '"Novikova, M."' showing total 17 results
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17 results on '"Novikova, M."'

1. [Biosynthesis of the polyene antibiotic levorin and the membrane composition of Streptomyces levoris].

Author

Novikova ML and Efimova TP

Subjects
Bacterial Proteins analysis, Candida metabolism, Cell Membrane analysis, Cell Membrane drug effects, Cell Membrane metabolism, Chromatography, Thin Layer, Membrane Lipids analysis, Membrane Proteins analysis, Phosphates pharmacology, Streptomyces analysis, Streptomyces drug effects, Antifungal Agents biosynthesis, Candicidin biosynthesis, Streptomyces metabolism
Abstract

Changes in the composition of Streptomyces levoris membranes were studied in the course of the polyene antibiotic levorin biosynthesis when the process was stimulated by Candida tropicalis metabolites and inhibited by inorganic phosphate. In the presence of stimulating compounds, the percentage of membranes increased in S. levoris cells and the membrane composition changed: the protein-to-lipid ratio and the concentration of total phosphorus decreased while the content of carbohydrates increased. Analysis of the lipid component showed that these changes were due to a gradual substitution of non-phosphorus glycolipids for membrane phospholipids and to an enrichment of the membranes with proteolipids. Such changes were not detected in a medium containing the inhibitor. It was for the first time that a considerable amount of the antibiotic produced by the culture was found in the membrane fractions. The data are discussed in relation with a possible role of the actinomycete membrane structures in levorin biosynthesis.

Published
1986

2. [The effect of lipase from Penicillium sp. on the membrane fraction of the levorin-producing Streptomyces levoris].

Author

Kazanina GA, Novikova ML, Efimova TP, and Selezneva AA

Subjects
Cell Membrane metabolism, Hydrolysis, Membrane Lipids metabolism, Antifungal Agents biosynthesis, Candicidin biosynthesis, Lipase metabolism, Penicillium enzymology, Streptomyces metabolism
Abstract

The effect of a lipase preparation from Penicillium sp. on the membranes of the levorin producer Streptomyces levoris was being studied. The enzyme preparation was found preferably to hydrolyse neutral lipids in the Str. levoris membranes, which makes it possible to use the lipase from Penicillium sp. for studying neutral lipids in microbial membranes.

Published
1988

7. [The role of structural elements of chloramphenicol in the molecular mechanism of its action].

Author

Telesnina GN, Novikova MA, Kolosov MN, and Shemiakin MM

Subjects
Anti-Bacterial Agents, Cell Membrane Permeability, Cell-Free System, Chemical Phenomena, Chemistry, Depression, Chemical, Escherichia coli drug effects, Escherichia coli growth & development, Propylene Glycols pharmacology, Ribosomes metabolism, Bacterial Proteins biosynthesis, Chloramphenicol pharmacology, Escherichia coli metabolism
Published
1968

8. [Effect of valinomycin on the respiration and transport of potassium ions in the mitochondria of yeast fungi].

Author

Murav'eva TI, Riabova ID, Oreshnikova NA, and Novikova MA

Subjects
Anions, Biological Transport drug effects, Culture Media, Dose-Response Relationship, Drug, Mitochondria drug effects, Oxidative Phosphorylation drug effects, Phosphates pharmacology, Protoplasts analysis, Saccharomyces, Stimulation, Chemical, Yeasts cytology, Yeasts drug effects, Mitochondria metabolism, Oxygen Consumption drug effects, Potassium metabolism, Valinomycin pharmacology, Yeasts metabolism
Published
1973

12. [Study of the action of valinomycin on yeasts].

Author

Murav'eva TI, Riabova ID, Oreshnikova NA, and Novikova MA

Subjects
Biological Transport drug effects, Culture Media, Depression, Chemical, Dose-Response Relationship, Drug, Microbial Sensitivity Tests, Potassium metabolism, Saccharomyces drug effects, Saccharomyces growth & development, Sodium metabolism, Time Factors, Yeasts growth & development, Valinomycin pharmacology, Yeasts drug effects
Published
1973

13. [Lipids from the regenerating rat liver].

Author

Vaver VA, Popkova GA, Novikova MA, and Bergel'son LD

Subjects
Animals, Cholesterol metabolism, Glycerides metabolism, Hepatectomy, Liver physiology, Lysophosphatidylcholines metabolism, Phosphatidylcholines metabolism, Phosphatidylethanolamines metabolism, Phosphatidylinositols metabolism, Phosphorus metabolism, Rats, Sphingomyelins metabolism, Time Factors, Triglycerides metabolism, Lipid Metabolism, Liver metabolism, Liver Regeneration, Phospholipids metabolism
Published
1969

15. [Characteristics of the inhibition of DNA synthesis by deoxyadenosine in tumor cells].

Author

Vornovitskaia GI, Ol'shanetskaia AD, Novikova MA, Karelina LP, and Morozova NS

Subjects
Animals, Ascites metabolism, DNA biosynthesis, In Vitro Techniques, Liver metabolism, Liver Neoplasms, Liver Regeneration, Phosphotransferases metabolism, RNA biosynthesis, RNA, Neoplasm biosynthesis, Rats, Syndrome, Thymidine Kinase metabolism, Carcinoma, Hepatocellular metabolism, DNA, Neoplasm biosynthesis, Deoxyadenosines pharmacology, Neoplasms, Experimental metabolism
Published
1972

16. [The action of cortisone on the synthesis of nucleic acids in sea-urchin embryos].

Author

Chestukhin AV and Novikova MA

Subjects
Animals, Carbon Isotopes, Cytosine biosynthesis, Depression, Chemical, Echinodermata, Embryo, Nonmammalian drug effects, Embryonic and Fetal Development, Thymine metabolism, Uridine metabolism, Cortisone pharmacology, DNA biosynthesis, Embryo, Nonmammalian metabolism, RNA, Messenger biosynthesis
Published
1969

17. [Thymidine- and thymidylate kinases from regenerating rat liver].

Author

Ol'shanetskaia AD, Karelina LP, and Novikova MA

Subjects
Animals, Hepatectomy, Kinetics, Liver Regeneration, Magnesium pharmacology, Nucleotides, Rats, Thymidine metabolism, Time Factors, Liver enzymology, Phosphotransferases biosynthesis, Thymidine Kinase biosynthesis
Published
1968

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