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1. [Comparative analysis of the interaction of various estrogens with the estrogen-receptor system of the uterus].

Author

Fanchenko ND, Alekseeva ML, Minina LS, Novikov EA, and Khel'mun DK

Subjects
Animals, Cytosol metabolism, Estradiol metabolism, Estriol metabolism, Estrone metabolism, Female, In Vitro Techniques, Kinetics, Rats, Rats, Inbred Strains, Estrogens metabolism, Receptors, Estrogen metabolism, Uterus metabolism
Abstract

Equilibrium binding of labeled estron, estradiol, estriol and DES was studied in uterine cytosol of immature Wistar rats. The dissociation kinetics of the ligand complexes with specific high affinity sites suggested the homogeneity of estrogen receptors in rat uterine cytosol. The feasibility of intracellular regulation of estrogen action in target cells both at the receptor and post-receptor levels is discussed.

Published
1985

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