1. [Computer simulation of hydraulic flows in a human eye].
- Author
-
Akhmanova MA, Domogatskiĭ SP, and Evgrafov VIu
- Subjects
- Anterior Eye Segment physiology, Choroid blood supply, Humans, Posterior Eye Segment physiology, Retinal Vessels physiology, Body Fluids physiology, Models, Biological, Ocular Physiological Phenomena
- Abstract
A two-dimensional computer model was developed to describe hydraulic flows inside the human eye. The flow field was described by coupled Navier-Stokes and Darcy equations. The velocity and pressure profiles in the chambers, the wall, and the vitreous body of the normal eye were obtained using the finite-element method. The model includes the filtration of fluid from the retinal capillary and its drainage through the choroid. The applications of this model include the investigation of the contribution of convection and diffusion to the transport of drugs and study of the kinetics of biodistribution in the eye.
- Published
- 2011