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Chailakhyan's views of sources of the origin of consciousness and mentality have been analyzed. It is supposed that the information interaction alone is not sufficient for the occurrence of consciousness. Something else is necessary that distinguishes a live system from lifeless and can be transmitted to the progeny and evolve. It is assumed that this is an "information-physical interaction", namely, a power profile of conformational reorganizations of proteins during their interaction. L.M. Chailakhyan proves the point of view that this profile during the interaction of proteins cannot be calculated and therefore cannot be cognized. This conclusion is supported by the Godel theorem of incompleteness.

A mathematical model quantitatively describing the value of secreted mediator per each successive impulse in the series of presynaptic impulses is presented. The model is plotted with the account taken of the role of presynaptic adrenoreceptors regulating noradrenaline secretion. It has been shown that a decrease observed in neurophysiological experiments and further stabilization of postsynaptic responses in the series of presynaptic impulses of given frequency are not connected with a decreased content of noradrenaline in nerve endings, but may be connected with the work of presynaptic alpha and beta adrenoreceptors.

A mathematical model is presented which quantitatively describes the value of secreted mediator and its dependence on the activity of autoadrenoreceptors in the series of presynaptic impulses. Suggestion that the first impulse in the series is the smallest and comes into the zone of sensitivity of presynaptic beta-adrenoreceptor in the model used facilitates the adrenergic synaptic transmission in the series of presynaptic impulsation experimentally described in synapses of vas deference. Conditions determining the synaptic depression and reduction in adrenergic transmission are analysed.

A mathematical model is presented which quantitatively describes the value of secreted mediator to each subsequent impulse in the series of presynaptic impulses. The model is constructed with the account taken of the role of presynaptic adrenoreceptors regulating noradrenaline secretion. An analysis of the model shows that the observed decrease and further stabilization of presynaptic responses in the series of presynaptic impulses observed in neurophysiological experiments can be connected with the work of alpha- and beta-autoadrenoreceptors. The increase of impulsation frequency affects the sensitivity of these receptors, which brings about an increase of concentration of secreted to each subsequent impulse mediator in the synaptic slit in the series of presynaptic impulses and stabilization of secretion at a higher level.