1. [Immunomodulating properties of various microbes--representatives of normal intestinal microflora].
- Author
-
Mal'tseva NN, Shkarupeta MM, Pinegin BV, and Korshunov VM
- Subjects
- Administration, Oral, Animals, Bacteroides fragilis immunology, Bifidobacterium immunology, Hot Temperature, Lactobacillus immunology, Mice, Streptococcus immunology, Immunity, Innate, Intestine, Small microbiology
- Abstract
The impact of oral administration of heat-killed bifidobacteria, lactobacteria, enterococci and bacteroides on mouse resistance to experimental salmonellosis and content of immunoglobulin-synthesizing cells in the proper plate of the small intestine was studied. It was shown that the administration of the killed bifidobacteria, lactobacteria and enterococci increased the animal resistance to experimental salmonellosis infection and induced an increase in the content of immunoglobulin-synthesizing cells in the proper plate of the small intestine. The administration of the killed bacteroides had no such effect. Possible development of bacterial preparations with immunomodulating properties based on killed bifidobacteria, lactobacteria or enterococci is discussed.
- Published
- 1992