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Your search keyword '"Giardiasis genetics"' showing total 2 results
Start Over Descriptor "Giardiasis genetics" Publisher izdatelstvo meditsina
2 results on '"Giardiasis genetics"'

1. [DETERMINATION OF GIARDIA DUODENALIS GENOTYPES IN LAMBLIA-INFESTED PEOPLE IN THE CITY OF MOSCOW].

Author

Kurnosova OP, Odoevskaya IM, and Krasavchenko KS

Subjects
Female, Giardia lamblia enzymology, Giardia lamblia isolation & purification, Giardiasis enzymology, Giardiasis epidemiology, Humans, Male, Moscow epidemiology, Genotype, Giardia lamblia genetics, Giardiasis genetics, Glyceraldehyde-3-Phosphate Dehydrogenases genetics, Protozoan Proteins genetics
Abstract

Our first experience in genotyping Giardia from Moscow residents, has shown that 4 and 2 of seven samples belong to G. duodenalis genotype A and genotype B, respectively; one sample was negative during amplification with two types of primers. Genotyping was Carried out using the specific primers TPIA and TPIB to the gene encoding for the enzyme triosephosphate isomerase from the parasite. Thus, further such investigations using a larger number of samples will be able to complement the epidemiology of Lamblia infection in Moscow residents.

Published
2015

2. [The characteristics of HLA antigen distribution among patients with persistent lambliasis].

Author

Osipova SO, Niiazova OP, Shimolin AP, and Dekhkan-Khodzhaeva NA

Subjects
Adolescent, Adult, Chi-Square Distribution, Child, Chronic Disease, Gene Frequency, Giardiasis ethnology, Giardiasis genetics, HLA Antigens genetics, Haplotypes, Humans, Middle Aged, Prospective Studies, Recurrence, Risk, Uzbekistan epidemiology, Giardiasis immunology, HLA Antigens blood
Abstract

Fifty patients suffering from persistent giardiasis and 257 healthy persons from Uzbekistan were examined. HLA-typing was carried out by the Terasaki microlymphocytotoxicity technique. The patients with persistent giardiasis were characterized as a significant prevalence of HLA-B5, HLA-B14, HLA-DR3, DR4, DR7 and haplotypes HLA-A9-B5 and A1-B5. These haplotypes and HLA antigens can be considered as markers of predisposition to persistent giardiasis.

Published
1994

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