Search

Your search keyword '"Lebedev AB"' showing total 2 results
Start Over Author "Lebedev AB" Publisher izd-vo meditsina
2 results on '"Lebedev AB"'

1. [Hepatoprotective effect of deanol aceglumate on experimental stress-induced gastropathy and diabetes mellitus].

Author

Blinov DS, Gogina ED, Krupnova TS, Balashov VP, blinova EV, Sadovnikov VN, Lebedev AB, and Nikitina OI

Subjects
Animals, Diabetes Mellitus, Experimental physiopathology, Mice, Peristalsis drug effects, Stomach blood supply, Stomach physiopathology, Stomach Ulcer physiopathology, Anti-Dyskinesia Agents pharmacology, Deanol pharmacology, Diabetes Mellitus, Experimental prevention & control, Stomach Ulcer prevention & control, Stress, Physiological
Abstract

Experiments on mice with streptozotocin-induced diabetes mellitus and stress-induced erosive ulcerous damage of the mucous membrane of stomach showed evidence of the preventive activity of deanol aceglumate in the course of peroral introduction at a dose of 250 mg/kg per 24 h during 4 days. This effect is accompanied by activation of the peristalsis of bowels and by an increase in the blood flow in the wall of stomach.

Published
2012

2. [Efficiency of etoxidol in treating cardiovascular disorders caused by experimental cerebral ischemia].

Author

Blinov DS, Sernov LN, Blinova EV, Balashov VP, Gogina ED, Van'kova LV, Skachilova SIa, Lebedev AB, and Belova LA

Subjects
Animals, Brain Ischemia physiopathology, Carotid Arteries physiopathology, Carotid Arteries surgery, Cats, Disease Models, Animal, Electrocardiography drug effects, Hemodynamics drug effects, Hypoxanthines administration & dosage, Hypoxanthines therapeutic use, Ligation adverse effects, Ligation methods, Myocardial Contraction drug effects, Pyridines administration & dosage, Pyridines chemical synthesis, Rats, Brain Ischemia drug therapy, Cerebrovascular Circulation drug effects, Pyridines therapeutic use
Abstract

A complex pharmacological study of the new cytoprotector drug etoksidol in animals with the disturbances of cerebral blood circulation showed that the intravenous introduction of the drug restores autonomous nomotopic driver of rhythm, conductivity in the atria and atrioventricular connection, and refractoriness of the atrioventricular connection, which were violated a result of sharp cerebral ischemia. The new drug does not suppress the inotropic function of the heart in cats and limits the dimensions of the zone of necrosis in rats with the myocardial infarction on the background of deficiency of the cerebral blood flow.

Published
2011

Catalog

Books, media, physical & digital resources
See catalog results