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Resistance to erythropoiesis-stimulating agents (ESA) in patients with renal anemia may be due to nutritional deficiencies affecting hematopoiesis. On the other hand, patients with advanced chronic kidney disease (CKD) generally consume a protein-restricted diet or a potassium-restricted diet. Therefore, we focused on the amount of nutrients, such as iron, zinc, copper, vitamin B6, vitamin B12, folic acid, vitamin C, and vitamin E, contained in various diets. We carried out a survey on the general diet, three protein-restricted diets, and two protein/potassium-restricted diets at a hospital in Japan. Then, based on each menu for five weeks, the amount of each nutrient contained in the daily diet was calculated. We found that the daily nutrient levels of iron, zinc, and vitamin B6 in all protein-restricted diets did not meet the estimated average requirement (EAR) for the Japanese population. Additionally, the vitamin C levels of protein/ potassium-restricted diets also did not meet the EAR for the Japanese population. These results suggest that patients on a diet that routinely limits their protein and/or potassium intake may be chronically deficient in the nutrients needed for hematopoiesis. Therefore, we think that pharmacists need to pay more attention to the diet and nutritional status of ESAresistant patients when managing their anemia, in our hospital. [ABSTRACT FROM AUTHOR]