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Start Over Author "Deliang Guo" Publisher ivyspring international publisher
2 results on '"Deliang Guo"'

2. Long noncoding RNA Linc01612 represses hepatocellular carcinoma progression by regulating miR-494/ATF3/p53 axis and promoting ubiquitination of YBX1

Author

Pengpeng, Liu, Qiu, Zhong, Youai, Song, Deliang, Guo, Dong, Ma, Baiyang, Chen, Jianwei, Lan, and Quanyan, Liu

Subjects
Activating Transcription Factor 3, Carcinoma, Hepatocellular, Liver Neoplasms, Ubiquitination, Cell Biology, Applied Microbiology and Biotechnology, Gene Expression Regulation, Neoplastic, MicroRNAs, Transcription Factor 3, Cell Line, Tumor, Disease Progression, Humans, RNA, Long Noncoding, Y-Box-Binding Protein 1, Tumor Suppressor Protein p53, Molecular Biology, Ecology, Evolution, Behavior and Systematics, Cell Proliferation, Developmental Biology
Abstract

Long noncoding RNAs (lncRNAs) play an important role in the progression of hepatocellular carcinoma (HCC). Linc01612 is a novel lncRNA that function remains unknown in the progression of cancers, including HCC. In this study, we discovered that Linc01612 is significantly down-regulated in HCC tissues than in non-tumor tissues and correlated with poor prognosis. Linc01612 mainly localizes in the cytoplasm and functions as a tumor suppressor by repressing the growth and metastasis of hepatoma cells

Published
2022

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