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This project demonstrates that modern commodity graphics cards (GPUs) can be used to perform fast Cartesian SENSE and k-t SENSE reconstruction. Specifically, the SENSE inversion is accelerated by up to two orders of magnitude and is no longer the time-limiting step. The achieved reconstruction times are now well below the acquisition times thus enabling real-time, interactive SENSE imaging, even with a large number of receive coils. The fast GPU reconstruction is also beneficial for datasets that are not acquired in real-time. We demonstrate it can be used for interactive adjustment of regularization parameters for k-t SENSE in the same way that one would adjust window and level settings. This enables a new way of performing imaging reconstruction, where the user chooses the setting of tuneable reconstruction parameters, in real-time, depending on the context in which the images are interpreted.