1. Imported case of Dengue virus 3 genotype I in Rio de Janeiro state, Brazil.
- Author
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Mendonça MCL, Mares-Guia MA, Rodrigues CDDS, Santos CCD, Chalhoub FLL, Araújo ESM, Chieppe AO, Nogueira RMR, and Filippis AMB
- Subjects
- Brazil, Dengue Virus isolation & purification, Genetic Variation, Humans, Phylogeny, Polymerase Chain Reaction, Sequence Analysis, DNA, Serogroup, Communicable Diseases, Imported virology, Dengue virology, Dengue Virus genetics, Genotype, Zika Virus genetics, Zika Virus Infection virology
- Abstract
The dengue virus (DENV), of the genus Flavivirus (Flaviviridae), has four antigenically distinct serotypes, of which DENV-3 is classified into five genotypes. Here, we describe the detection of DENV-3 genotype I in sera of a Brazilian patient travelling from Singapore to Rio de Janeiro, Brazil, by using multiplex real-time RT-PCR, DNA sequencing of the whole envelope protein gene, and phylogenetic analysis. The virus shares ancestry with those identified in Bali, Indonesia, in 2015. It is possible that arboviruses such as Chikungunya ECSA genotype, DENV-4 genotype I, and Zika were introduced in Brazil from other continents during the multiple international events hosted by the country over the last four years, including World Youth Day, the Soccer World Cup, and the Summer Olympics.
- Published
- 2018
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