1. Characterisation of ocular involvement in an experimental model of neuroschistosomiasis mansoni
- Author
-
Helena Hollanda Santos, Daniel Vitor Vasconcelos-Santos, Patrícia Martins Parreiras, José Roberto Lambertucci, Thiago Andre Alves Fidelis, Marco Vinícius Chaud, Neusa Araújo, Paulo Marcos Zech Coelho, and Geraldo Brasileiro-Filho
- Subjects
Male ,Microbiology (medical) ,medicine.medical_specialty ,Pathology ,lcsh:Arctic medicine. Tropical medicine ,Conjunctiva ,genetic structures ,lcsh:RC955-962 ,Short Communication ,Ocular Pathology ,030231 tropical medicine ,lcsh:QR1-502 ,ocular lesion ,Schistosomiasis ,Lacrimal gland ,Lacrimal apparatus ,lcsh:Microbiology ,Mice ,03 medical and health sciences ,0302 clinical medicine ,Corneoscleral Limbus ,parasitic diseases ,medicine ,Animals ,Eye Infections, Parasitic ,neuroschistosomiasis ,business.industry ,Schistosoma mansoni ,medicine.disease ,Schistosomiasis mansoni ,eye diseases ,eye granuloma ,Disease Models, Animal ,medicine.anatomical_structure ,Histopathology ,Choroid ,sense organs ,business ,Brazil - Abstract
The Global Burden of Disease Study 2010 listed schistosomiasis among the leading 100 causes of death in Brazil, responsible for 3.6% of the estimated total of deaths globally. Eye and adnexa are very rarely affected by schistosomiasis mansoni, with limited documentation of ocular pathology in this setting. This short communication reports ocular histolopathological findings in a murine model of neuroschistosomiasis mansoni. Lesions were found in the bulbar conjunctiva, lacrimal gland, choroid and corneoscleral limbus.
- Published
- 2019