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Objective: Heart failure, respiratory failure and kidney failure are three severe organ failures (OF) that have high mortalities and are most prevalent in intensive care units. The objective of this work is to offer insights into OF clustering from the aspects of graph neural networks and diagnosis history., Methods: This paper proposes a neural network-based pipeline to cluster three types of organ failure patients by incorporating embedding pre-train using an ontology graph of the International Classification of Diseases (ICD) codes. We employ an autoencoder-based deep clustering architecture jointly trained with a K-means loss, and a non-linear dimension reduction is performed to obtain patient clusters on the MIMIC-III dataset., Results: The clustering pipeline shows superior performance on a public-domain image dataset. On the MIMIC-III dataset, it discovers two distinct clusters that exhibit different comorbidity spectra which can be related to the severity of diseases. The proposed pipeline is compared with several other clustering models and shows superiority., Conclusion: Our proposed pipeline gives stable clusters, however, they do not correspond to the type of OF which indicates these OF share significant hidden characteristics in diagnosis. These clusters can be used to signal possible complications and severity of illness and aid personalised treatment., Significance: We are the first to apply an unsupervised approach to offer insights from a biomedical engineering perspective on these three types of organ failure, and publish the pre-trained embeddings for future transfer learning.

Food intake monitoring can play an important role in the prevention of malnutrition in the aging population, but traditional tools may not be adequate for use in this target group. These tools typically involve the use of questionnaires or food diaries that require manual data entry. Due to their time-consuming nature, they are often incomplete, contain mistakes, or not used at all. An alternative to self-reporting tools, in the form of a plate system that automatically measures the consumed food during the meal, is presented in this paper. Furthermore, the system can estimate the location where each bite was taken on the plate. The system is compatible with an off-the-shelf plate that is mounted on top of a base station. Weight sensors are integrated in the base, allowing for easy removal and cleaning of the plate. Localization of bites is done by looking at the movement of the center of mass during eating. When used with a compartmentalized plate, the amount of consumed food per compartment can be measured. With prior knowledge of the type of food in each compartment, this can give an indication of calories and nutritional intake. We present a bite detection algorithm using a random forest decision tree classifier. Data from 24 aging adults (ages 52-95) eating a single meal with chopsticks was used to train and evaluate the model. Out of a total of 836 true annotated bites, the algorithm detected 602 with a precision and recall of 0.78 and 0.76, respectively. By summing the weights of detected bites from each compartment, the algorithm was able to estimate the amount of food taken per compartment with an average error of (8 ±8)% of the portion size.