1. Error grid analysis of noninvasive glucose monitoring via gingival crevicular fluid.
- Author
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Yamaguchi M, Kambe S, Yamazaki K, and Kobayashi M
- Subjects
- Adult, Blood Glucose Self-Monitoring methods, Data Interpretation, Statistical, Diagnosis, Computer-Assisted methods, Equipment Design, Equipment Failure Analysis, Female, Humans, Male, Reproducibility of Results, Sensitivity and Specificity, Specimen Handling methods, Blood Glucose Self-Monitoring instrumentation, Diabetes Mellitus blood, Diabetes Mellitus diagnosis, Diagnosis, Computer-Assisted instrumentation, Gingival Crevicular Fluid chemistry, Specimen Handling instrumentation
- Abstract
In order to realize a noninvasive blood glucose monitor, we monitored the gingival crevicular fluid (GCF). In this paper, the clinical evaluations were performed on not only normal subjects but also diabetic subjects using a GCF-glucose monitor to determine blood glucose levels. Meal load tests were carried out and the time-course changes in blood glucose level and GCF glucose level were measured continuously. A positive correlation of more than 0.9 was found between blood glucose level and GCF glucose level, necessitating the calibration of individual correlations for every subject. Finally, the performance of the GCF-glucose monitor was evaluated using Error Grid Analysis. As the results, significant information for the glucose level decision was obtained not only for normal subjects, but also for diabetic subjects.
- Published
- 2005
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